etynodiol-6479 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the etynodiol-6479 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADGRA2 adhesion G protein-coupled receptor A2
ADGRL1 adhesion G protein-coupled receptor L1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APC adenomatous polyposis coli
AQP1 aquaporin 1 (Colton blood group)
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
C1ORF54 chromosome 1 open reading frame 54
C2ORF27A chromosome 2 open reading frame 27A
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD6 CD6 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CLGN calmegin
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSNK1G1 casein kinase 1, gamma 1
CSPP1 centrosome and spindle pole associated protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
DFNB31 deafness, autosomal recessive 31
DGKI diacylglycerol kinase, iota
EGR3 early growth response 3
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELOVL5 ELOVL fatty acid elongase 5
EMP1 epithelial membrane protein 1
FAXDC2 fatty acid hydroxylase domain containing 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FHL1 four and a half LIM domains 1
FOXF1 forkhead box F1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAR1 GAR1 ribonucleoprotein
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPATCH4 G patch domain containing 4
GPR1 G protein-coupled receptor 1
GRIP2 glutamate receptor interacting protein 2
ICA1 islet cell autoantigen 1, 69kDa
IZUMO4 IZUMO family member 4
JAK2 Janus kinase 2
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0125 KIAA0125
LOC730101 uncharacterized LOC730101
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBD1 methyl-CpG binding domain protein 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NBL1 neuroblastoma 1, DAN family BMP antagonist
NKX3-2 NK3 homeobox 2
NPY1R neuropeptide Y receptor Y1
PALM paralemmin
PAX2 paired box 2
PAX5 paired box 5
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDZK1 PDZ domain containing 1
PER3 period circadian clock 3
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POFUT1 protein O-fucosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKD1 protein kinase D1
PURG purine-rich element binding protein G
RIMS2 regulating synaptic membrane exocytosis 2
SAYSD1 SAYSVFN motif domain containing 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIK3 SIK family kinase 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMG6 SMG6 nonsense mediated mRNA decay factor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
SQLE squalene epoxidase
SRSF1 serine/arginine-rich splicing factor 1
TGFA transforming growth factor, alpha
TMEM144 transmembrane protein 144
TMEM63A transmembrane protein 63A
TTC38 tetratricopeptide repeat domain 38
TTC39A tetratricopeptide repeat domain 39A
TUBA3C tubulin, alpha 3c
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF407 zinc finger protein 407
ZNF493 zinc finger protein 493
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAM2 ADAM metallopeptidase domain 2
ADTRP androgen-dependent TFPI-regulating protein
APOC4 apolipoprotein C-IV
ARC activity-regulated cytoskeleton-associated protein
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
ATXN2 ataxin 2
BAG4 BCL2-associated athanogene 4
C2ORF44 chromosome 2 open reading frame 44
C7ORF69 chromosome 7 open reading frame 69
CALB2 calbindin 2
CCNT1 cyclin T1
CCRL2 chemokine (C-C motif) receptor-like 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDH10 cadherin 10, type 2 (T2-cadherin)
CFAP45 cilia and flagella associated protein 45
CLCA1 chloride channel accessory 1
CLDN17 claudin 17
CLIC2 chloride intracellular channel 2
CLSPN claspin
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DRD1 dopamine receptor D1
FBXL6 F-box and leucine-rich repeat protein 6
FBXO2 F-box protein 2
FRS2 fibroblast growth factor receptor substrate 2
GALK1 galactokinase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPR3 G protein-coupled receptor 3
GRTP1 growth hormone regulated TBC protein 1
GSTP1 glutathione S-transferase pi 1
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1E histone cluster 1, H1e
HIST1H2BJ histone cluster 1, H2bj
HIST1H4D histone cluster 1, H4d
HSPB6 heat shock protein, alpha-crystallin-related, B6
IDI2-AS1 IDI2 antisense RNA 1
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
IPO8 importin 8
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF3 Kruppel-like factor 3 (basic)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LARP6 La ribonucleoprotein domain family, member 6
LINC00597 long intergenic non-protein coding RNA 597
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100131532 uncharacterized LOC100131532
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD1 neuronal differentiation 1
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAIP2B poly(A) binding protein interacting protein 2B
PEX26 peroxisomal biogenesis factor 26
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PRDM14 PR domain containing 14
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RCAN3 RCAN family member 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCHIP1 schwannomin interacting protein 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STEAP4 STEAP family member 4
STON1 stonin 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCTN1 tectonic family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VLDLR very low density lipoprotein receptor
WDR76 WD repeat domain 76
XDH xanthine dehydrogenase
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF134 zinc finger protein 134
ZNF408 zinc finger protein 408