etomidate-7460 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the etomidate-7460 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
AEBP1 AE binding protein 1
AFF1 AF4/FMR2 family, member 1
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
C2ORF72 chromosome 2 open reading frame 72
CCPG1 cell cycle progression 1
CCR9 chemokine (C-C motif) receptor 9
CD247 CD247 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP290 centrosomal protein 290kDa
COL1A1 collagen, type I, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DMC1 DNA meiotic recombinase 1
DOK4 docking protein 4
DRD2 dopamine receptor D2
DST dystonin
ECE1 endothelin converting enzyme 1
EHBP1L1 EH domain binding protein 1-like 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPHA1 EPH receptor A1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM120C family with sequence similarity 120C
FECH ferrochelatase
FLOT1 flotillin 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD1 frizzled class receptor 1
GPR137 G protein-coupled receptor 137
GPR153 G protein-coupled receptor 153
IDS iduronate 2-sulfatase
IGL immunoglobulin lambda locus
IGSF6 immunoglobulin superfamily, member 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JAM3 junctional adhesion molecule 3
KIF1A kinesin family member 1A
LHX2 LIM homeobox 2
LTBP4 latent transforming growth factor beta binding protein 4
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MATK megakaryocyte-associated tyrosine kinase
MVP major vault protein
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAAA N-acylethanolamine acid amidase
NCAPH2 non-SMC condensin II complex, subunit H2
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PALM paralemmin
PCDHA9 protocadherin alpha 9
PDE4DIP phosphodiesterase 4D interacting protein
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POMT2 protein-O-mannosyltransferase 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCA protein kinase C, alpha
PRSS3 protease, serine, 3
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RCAN3 RCAN family member 3
RIMS3 regulating synaptic membrane exocytosis 3
RIN3 Ras and Rab interactor 3
RNF122 ring finger protein 122
RPL7 ribosomal protein L7
SH3D21 SH3 domain containing 21
SIRT3 sirtuin 3
SIX1 SIX homeobox 1
SLAMF8 SLAM family member 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMAD1 SMAD family member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK11 serine/threonine kinase 11
STX7 syntaxin 7
SYCP2 synaptonemal complex protein 2
SYMPK symplekin
T T, brachyury homolog (mouse)
TADA2A transcriptional adaptor 2A
TAZ tafazzin
TEX40 testis expressed 40
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM161A transmembrane protein 161A
TRPM4 transient receptor potential cation channel, subfamily M, member 4
USF2 upstream transcription factor 2, c-fos interacting
VAV1 vav 1 guanine nucleotide exchange factor
VEGFB vascular endothelial growth factor B
VPS9D1 VPS9 domain containing 1
WWC1 WW and C2 domain containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC11 zinc finger, DHHC-type containing 11
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF747 zinc finger protein 747
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASB6 ankyrin repeat and SOCS box containing 6
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AZI2 5-azacytidine induced 2
BAK1 BCL2-antagonist/killer 1
BBC3 BCL2 binding component 3
C21ORF91 chromosome 21 open reading frame 91
C5ORF30 chromosome 5 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC15 coiled-coil domain containing 15
CCDC186 coiled-coil domain containing 186
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPQ centromere protein Q
CEP72 centrosomal protein 72kDa
CLK1 CDC-like kinase 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTC1 CTS telomere maintenance complex component 1
CTNNBIP1 catenin, beta interacting protein 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF13 DDB1 and CUL4 associated factor 13
DHDDS dehydrodolichyl diphosphate synthase
DIXDC1 DIX domain containing 1
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
ECHDC2 enoyl CoA hydratase domain containing 2
EFNA3 ephrin-A3
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FBXO31 F-box protein 31
FMO4 flavin containing monooxygenase 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FYCO1 FYVE and coiled-coil domain containing 1
GALK1 galactokinase 1
GATA6 GATA binding protein 6
GCHFR GTP cyclohydrolase I feedback regulator
GLB1L2 galactosidase, beta 1-like 2
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
HDAC11 histone deacetylase 11
HIST1H4J histone cluster 1, H4j
HMOX1 heme oxygenase 1
HPN hepsin
INSIG2 insulin induced gene 2
KIAA0895 KIAA0895
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00339 long intergenic non-protein coding RNA 339
LINS lines homolog (Drosophila)
LTBP2 latent transforming growth factor beta binding protein 2
LUZP1 leucine zipper protein 1
MAMLD1 mastermind-like domain containing 1
METTL1 methyltransferase like 1
METTL2B methyltransferase like 2B
MIR22HG MIR22 host gene
MOSPD3 motile sperm domain containing 3
MTMR11 myotubularin related protein 11
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PRODH proline dehydrogenase (oxidase) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTCD2 pentatricopeptide repeat domain 2
PTK6 protein tyrosine kinase 6
PVRL3 poliovirus receptor-related 3
R3HCC1L R3H domain and coiled-coil containing 1-like
RALGDS ral guanine nucleotide dissociation stimulator
RNF25 ring finger protein 25
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC25A40 solute carrier family 25, member 40
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SSNA1 Sjogren syndrome nuclear autoantigen 1
STK16 serine/threonine kinase 16
TASP1 taspase, threonine aspartase, 1
TCTN2 tectonic family member 2
TRAF2 TNF receptor-associated factor 2
TWF2 twinfilin actin binding protein 2
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
ZBTB39 zinc finger and BTB domain containing 39
ZNF14 zinc finger protein 14
ZNF586 zinc finger protein 586
ZNF611 zinc finger protein 611