etofenamate-2907 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the etofenamate-2907 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM22 ADAM metallopeptidase domain 22
ADD2 adducin 2 (beta)
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANGPT4 angiopoietin 4
AREG amphiregulin
ARSD arylsulfatase D
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C1ORF105 chromosome 1 open reading frame 105
CDC42 cell division cycle 42
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DUSP4 dual specificity phosphatase 4
DVL2 dishevelled segment polarity protein 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FER1L4 fer-1-like family member 4, pseudogene (functional)
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF4 fibroblast growth factor 4
FURIN furin (paired basic amino acid cleaving enzyme)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GRIK5 glutamate receptor, ionotropic, kainate 5
GYPB glycophorin B (MNS blood group)
HFE hemochromatosis
HIST1H2AJ histone cluster 1, H2aj
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGHM immunoglobulin heavy constant mu
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAOA monoamine oxidase A
MIR600HG MIR600 host gene
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTRF1L mitochondrial translational release factor 1-like
MYH14 myosin, heavy chain 14, non-muscle
MYO6 myosin VI
NAAA N-acylethanolamine acid amidase
NBEA neurobeachin
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NF2 neurofibromin 2 (merlin)
NINJ2 ninjurin 2
NLRP1 NLR family, pyrin domain containing 1
NPFFR1 neuropeptide FF receptor 1
NPPA natriuretic peptide A
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM7 PDZ and LIM domain 7 (enigma)
PLCL2 phospholipase C-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTCH2 patched 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PURG purine-rich element binding protein G
PVR poliovirus receptor
RGS14 regulator of G-protein signaling 14
RNF39 ring finger protein 39
RPL10 ribosomal protein L10
RPL23AP53 ribosomal protein L23a pseudogene 53
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS3A ribosomal protein S3A
RUFY3 RUN and FYVE domain containing 3
RUNDC3A RUN domain containing 3A
SARM1 sterile alpha and TIR motif containing 1
SCAMP5 secretory carrier membrane protein 5
SELPLG selectin P ligand
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC48A1 solute carrier family 48 (heme transporter), member 1
SP140 SP140 nuclear body protein
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SULF1 sulfatase 1
TM4SF20 transmembrane 4 L six family member 20
TNS1 tensin 1
TRD T cell receptor delta locus
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
ZFHX2 zinc finger homeobox 2
ZNF280B zinc finger protein 280B
ZNF385D zinc finger protein 385D
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACAD10 acyl-CoA dehydrogenase family, member 10
ACYP2 acylphosphatase 2, muscle type
AMT aminomethyltransferase
APH1B APH1B gamma secretase subunit
APOL6 apolipoprotein L, 6
ATF3 activating transcription factor 3
C11ORF21 chromosome 11 open reading frame 21
C14ORF159 chromosome 14 open reading frame 159
CCDC69 coiled-coil domain containing 69
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD69 CD69 molecule
CDK3 cyclin-dependent kinase 3
CENPJ centromere protein J
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHKB choline kinase beta
CHMP1A charged multivesicular body protein 1A
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAAF2 dynein, axonemal, assembly factor 2
DUSP5 dual specificity phosphatase 5
DUSP8 dual specificity phosphatase 8
ECM1 extracellular matrix protein 1
EDC3 enhancer of mRNA decapping 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR2 early growth response 2
EGR3 early growth response 3
EHBP1L1 EH domain binding protein 1-like 1
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHA4 EPH receptor A4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC6 excision repair cross-complementation group 6
FEM1C fem-1 homolog c (C. elegans)
FLCN folliculin
G6PD glucose-6-phosphate dehydrogenase
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPATCH3 G patch domain containing 3
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFLR1 IGF-like family receptor 1
IL1RAP interleukin 1 receptor accessory protein
INF2 inverted formin, FH2 and WH2 domain containing
IRF7 interferon regulatory factor 7
KIAA0355 KIAA0355
KLHL26 kelch-like family member 26
LNPEP leucyl/cystinyl aminopeptidase
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRK1 leucine-rich repeat kinase 1
MAP1S microtubule-associated protein 1S
MAP3K7CL MAP3K7 C-terminal like
MAVS mitochondrial antiviral signaling protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUM1 melanoma associated antigen (mutated) 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYO1E myosin IE
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NPDC1 neural proliferation, differentiation and control, 1
NTSR1 neurotensin receptor 1 (high affinity)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PIR pirin (iron-binding nuclear protein)
PNOC prepronociceptin
POLM polymerase (DNA directed), mu
POR P450 (cytochrome) oxidoreductase
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PTCD1 pentatricopeptide repeat domain 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RBM42 RNA binding motif protein 42
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL13P5 ribosomal protein L13 pseudogene 5
SECISBP2 SECIS binding protein 2
SMAD7 SMAD family member 7
SND1-IT1 SND1 intronic transcript 1
SNX16 sorting nexin 16
STAP1 signal transducing adaptor family member 1
TBC1D17 TBC1 domain family, member 17
TCTN2 tectonic family member 2
THOP1 thimet oligopeptidase 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNNT1 troponin T type 1 (skeletal, slow)
TSPYL2 TSPY-like 2
UPB1 ureidopropionase, beta
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
YEATS4 YEATS domain containing 4
ZBTB25 zinc finger and BTB domain containing 25
ZNF222 zinc finger protein 222
ZNF468 zinc finger protein 468