etodolac-7246 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the etodolac-7246 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AIM1L absent in melanoma 1-like
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOC4 apolipoprotein C-IV
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARL1 ADP-ribosylation factor-like 1
ATF3 activating transcription factor 3
B9D1 B9 protein domain 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BRCA1 breast cancer 1, early onset
BTN2A1 butyrophilin, subfamily 2, member A1
C10ORF76 chromosome 10 open reading frame 76
C16ORF58 chromosome 16 open reading frame 58
C9ORF156 chromosome 9 open reading frame 156
CA9 carbonic anhydrase IX
CCKAR cholecystokinin A receptor
CDK13 cyclin-dependent kinase 13
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
COL13A1 collagen, type XIII, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CXCL3 chemokine (C-X-C motif) ligand 3
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DTX2 deltex 2, E3 ubiquitin ligase
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERAP1 endoplasmic reticulum aminopeptidase 1
FBN2 fibrillin 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR1 fibroblast growth factor receptor 1
FKBP8 FK506 binding protein 8, 38kDa
FLJ21369 uncharacterized protein FLJ21369
GABARAPL1 GABA(A) receptor-associated protein like 1
GLRB glycine receptor, beta
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPX2 glutathione peroxidase 2
HDAC11 histone deacetylase 11
HERC2P3 hect domain and RLD 2 pseudogene 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMHB1 histocompatibility (minor) HB-1
IGHM immunoglobulin heavy constant mu
INO80B INO80 complex subunit B
INTS6 integrator complex subunit 6
IRF8 interferon regulatory factor 8
LAMA4 laminin, alpha 4
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LSP1 lymphocyte-specific protein 1
MAPK12 mitogen-activated protein kinase 12
MAPK7 mitogen-activated protein kinase 7
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MYO9B myosin IXB
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOTCH3 notch 3
NOV nephroblastoma overexpressed
NPEPL1 aminopeptidase-like 1
NRXN3 neurexin 3
NUMA1 nuclear mitotic apparatus protein 1
OASL 2'-5'-oligoadenylate synthetase-like
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGK1 phosphoglycerate kinase 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLIN2 perilipin 2
PML promyelocytic leukemia
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRMT7 protein arginine methyltransferase 7
RAD54B RAD54 homolog B (S. cerevisiae)
RASA2 RAS p21 protein activator 2
RGS4 regulator of G-protein signaling 4
RHOBTB2 Rho-related BTB domain containing 2
RWDD2A RWD domain containing 2A
SAPCD1 suppressor APC domain containing 1
SERTAD3 SERTA domain containing 3
SH2B1 SH2B adaptor protein 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMG6 SMG6 nonsense mediated mRNA decay factor
SMG7 SMG7 nonsense mediated mRNA decay factor
SS18 synovial sarcoma translocation, chromosome 18
STBD1 starch binding domain 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TK2 thymidine kinase 2, mitochondrial
TLE4 transducin-like enhancer of split 4
TM2D1 TM2 domain containing 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNRC6B trinucleotide repeat containing 6B
TOX4 TOX high mobility group box family member 4
TRIM25 tripartite motif containing 25
TUBD1 tubulin, delta 1
ZFPL1 zinc finger protein-like 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF408 zinc finger protein 408
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR2A activin A receptor, type IIA
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BAMBI BMP and activin membrane-bound inhibitor
C11ORF68 chromosome 11 open reading frame 68
C1ORF112 chromosome 1 open reading frame 112
C8ORF60 chromosome 8 open reading frame 60
CASC3 cancer susceptibility candidate 3
CASP8AP2 caspase 8 associated protein 2
CCDC176 coiled-coil domain containing 176
CCDC69 coiled-coil domain containing 69
CCNT1 cyclin T1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRABP2 cellular retinoic acid binding protein 2
CRIP2 cysteine-rich protein 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFCAB2 EF-hand calcium binding domain 2
ENDOG endonuclease G
EPHA4 EPH receptor A4
FABP4 fatty acid binding protein 4, adipocyte
FBXL2 F-box and leucine-rich repeat protein 2
GLI3 GLI family zinc finger 3
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GSDMD gasdermin D
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AE histone cluster 1, H2ae
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HYAL3 hyaluronoglucosaminidase 3
KLK5 kallikrein-related peptidase 5
KRT6A keratin 6A, type II
LMBR1L limb development membrane protein 1-like
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAGEA6 melanoma antigen family A6
MBD5 methyl-CpG binding domain protein 5
METTL2B methyltransferase like 2B
MLF2 myeloid leukemia factor 2
MPST mercaptopyruvate sulfurtransferase
MRPS34 mitochondrial ribosomal protein S34
MST1R macrophage stimulating 1 receptor
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYO19 myosin XIX
NADSYN1 NAD synthetase 1
NINJ1 ninjurin 1
NUPL1 nucleoporin like 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCBP4 poly(rC) binding protein 4
PCNT pericentrin
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PNRC1 proline-rich nuclear receptor coactivator 1
POR P450 (cytochrome) oxidoreductase
PPAN peter pan homolog (Drosophila)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PXDC1 PX domain containing 1
RAB8B RAB8B, member RAS oncogene family
RANBP17 RAN binding protein 17
REPS2 RALBP1 associated Eps domain containing 2
RHOB ras homolog family member B
RNF31 ring finger protein 31
RPGR retinitis pigmentosa GTPase regulator
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SDC3 syndecan 3
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SOBP sine oculis binding protein homolog (Drosophila)
SPATA7 spermatogenesis associated 7
STIM1 stromal interaction molecule 1
STX1A syntaxin 1A (brain)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TEX264 testis expressed 264
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM132A transmembrane protein 132A
TMEM159 transmembrane protein 159
TMSB15B thymosin beta 15B
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TRIM21 tripartite motif containing 21
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSKU tsukushi, small leucine rich proteoglycan
TWF2 twinfilin actin binding protein 2
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB48 zinc finger and BTB domain containing 48
ZNF273 zinc finger protein 273
ZNF813 zinc finger protein 813
ZSCAN31 zinc finger and SCAN domain containing 31
ZSCAN9 zinc finger and SCAN domain containing 9