etilefrine-4590 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the etilefrine-4590 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKAP12 A kinase (PRKA) anchor protein 12
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
AQP3 aquaporin 3 (Gill blood group)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2A1 BCL2-related protein A1
BMP2 bone morphogenetic protein 2
C5 complement component 5
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CLDN8 claudin 8
CLEC11A C-type lectin domain family 11, member A
CREM cAMP responsive element modulator
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
DFNB31 deafness, autosomal recessive 31
DMBT1 deleted in malignant brain tumors 1
DNASE1L3 deoxyribonuclease I-like 3
DOK5 docking protein 5
DUSP1 dual specificity phosphatase 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPAS1 endothelial PAS domain protein 1
ETV1 ets variant 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FLJ42627 uncharacterized LOC645644
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
IGL immunoglobulin lambda locus
IL11 interleukin 11
IL1R2 interleukin 1 receptor, type II
IL1RL1 interleukin 1 receptor-like 1
IL33 interleukin 33
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK2 Janus kinase 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1654 KIAA1654 protein
KLHL28 kelch-like family member 28
KRIT1 KRIT1, ankyrin repeat containing
KRT17 keratin 17, type I
LIG3 ligase III, DNA, ATP-dependent
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LYPD3 LY6/PLAUR domain containing 3
MAP7 microtubule-associated protein 7
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCAPH2 non-SMC condensin II complex, subunit H2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSBP2 oxysterol binding protein 2
OXCT2 3-oxoacid CoA transferase 2
PALM paralemmin
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDS5A PDS5 cohesin associated factor A
PHF14 PHD finger protein 14
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRR5 proline rich 5 (renal)
PTGES prostaglandin E synthase
PTGFR prostaglandin F receptor (FP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM34 RNA binding motif protein 34
RGS12 regulator of G-protein signaling 12
RNGTT RNA guanylyltransferase and 5'-phosphatase
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCEL sciellin
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SIRT4 sirtuin 4
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMOX spermine oxidase
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STC1 stanniocalcin 1
TBC1D30 TBC1 domain family, member 30
TBL1X transducin (beta)-like 1X-linked
TGFB2 transforming growth factor, beta 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIM29 tripartite motif containing 29
TTC38 tetratricopeptide repeat domain 38
TTC39A tetratricopeptide repeat domain 39A
ZNF219 zinc finger protein 219
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADGRB2 adhesion G protein-coupled receptor B2
ADRB2 adrenoceptor beta 2, surface
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASAP1-IT1 ASAP1 intronic transcript 1
BEND5 BEN domain containing 5
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C5ORF45 chromosome 5 open reading frame 45
CASZ1 castor zinc finger 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKN2AIP CDKN2A interacting protein
CDON cell adhesion associated, oncogene regulated
CINP cyclin-dependent kinase 2 interacting protein
CLCA1 chloride channel accessory 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPNE7 copine VII
CSF1R colony stimulating factor 1 receptor
CTGF connective tissue growth factor
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
FBXL7 F-box and leucine-rich repeat protein 7
FJX1 four jointed box 1 (Drosophila)
FURIN furin (paired basic amino acid cleaving enzyme)
G0S2 G0/G1 switch 2
GAS8 growth arrest-specific 8
GBX2 gastrulation brain homeobox 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPATCH2 G patch domain containing 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
GUSBP3 glucuronidase, beta pseudogene 3
HDAC9 histone deacetylase 9
HIST1H2BO histone cluster 1, H2bo
HIST1H4E histone cluster 1, H4e
HOXB9 homeobox B9
INHBB inhibin, beta B
KIAA0513 KIAA0513
LIG4 ligase IV, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LINC00597 long intergenic non-protein coding RNA 597
LMCD1 LIM and cysteine-rich domains 1
MEGF8 multiple EGF-like-domains 8
MFSD6 major facilitator superfamily domain containing 6
MGP matrix Gla protein
MYL5 myosin, light chain 5, regulatory
MYO1F myosin IF
NPY1R neuropeptide Y receptor Y1
NT5M 5',3'-nucleotidase, mitochondrial
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2G15 phospholipase A2, group XV
POLH polymerase (DNA directed), eta
PROX1 prospero homeobox 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTX3 pentraxin 3, long
PXDC1 PX domain containing 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS17 regulator of G-protein signaling 17
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUNDC3B RUN domain containing 3B
SCG5 secretogranin V
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOBP sine oculis binding protein homolog (Drosophila)
SPEG SPEG complex locus
SYNPO synaptopodin
SYT17 synaptotagmin XVII
TEAD3 TEA domain family member 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM159 transmembrane protein 159
TOM1 target of myb1 (chicken)
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
WNT7A wingless-type MMTV integration site family, member 7A
ZMAT5 zinc finger, matrin-type 5
ZNF253 zinc finger protein 253
ZNF343 zinc finger protein 343
ZNF385D zinc finger protein 385D
ZNF671 zinc finger protein 671