etidronic acid-4387 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the etidronic acid-4387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADRA2B adrenoceptor alpha 2B
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
B9D1 B9 protein domain 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1ORF21 chromosome 1 open reading frame 21
CABP2 calcium binding protein 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC85B coiled-coil domain containing 85B
CCL19 chemokine (C-C motif) ligand 19
CCL23 chemokine (C-C motif) ligand 23
CCR8 chemokine (C-C motif) receptor 8
CCRL2 chemokine (C-C motif) receptor-like 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CFAP69 cilia and flagella associated protein 69
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
COL4A1 collagen, type IV, alpha 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTNS cystinosin, lysosomal cystine transporter
CXCR2 chemokine (C-X-C motif) receptor 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EDN1 endothelin 1
EFR3B EFR3 homolog B (S. cerevisiae)
FGF18 fibroblast growth factor 18
FRAS1 Fraser extracellular matrix complex subunit 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR182 G protein-coupled receptor 182
GPR85 G protein-coupled receptor 85
GREB1L growth regulation by estrogen in breast cancer-like
HCRTR2 hypocretin (orexin) receptor 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IGLJ3 immunoglobulin lambda joining 3
INHBE inhibin, beta E
IQCK IQ motif containing K
ITM2C integral membrane protein 2C
KIAA1109 KIAA1109
KIDINS220 kinase D-interacting substrate, 220kDa
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
LAT2 linker for activation of T cells family, member 2
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC17 leucine rich repeat containing 17
LSP1 lymphocyte-specific protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAOA monoamine oxidase A
MNDA myeloid cell nuclear differentiation antigen
NCAM1 neural cell adhesion molecule 1
NID1 nidogen 1
NIPAL3 NIPA-like domain containing 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBPL3 oxysterol binding protein-like 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIP prolactin-induced protein
PLAT plasminogen activator, tissue
PLCE1 phospholipase C, epsilon 1
PON3 paraoxonase 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRF1 perforin 1 (pore forming protein)
PRKCQ protein kinase C, theta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RIMS1 regulating synaptic membrane exocytosis 1
SAA3P serum amyloid A3 pseudogene
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SIGLEC7 sialic acid binding Ig-like lectin 7
SLAMF7 SLAM family member 7
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAP25 synaptosomal-associated protein, 25kDa
SNRPN small nuclear ribonucleoprotein polypeptide N
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPN sialophorin
SRSF7 serine/arginine-rich splicing factor 7
SSX3 synovial sarcoma, X breakpoint 3
STS steroid sulfatase (microsomal), isozyme S
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBX6 T-box 6
TCF25 transcription factor 25 (basic helix-loop-helix)
TEX40 testis expressed 40
THPO thrombopoietin
TONSL tonsoku-like, DNA repair protein
TRIM3 tripartite motif containing 3
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
XCR1 chemokine (C motif) receptor 1
ZIM2 zinc finger, imprinted 2

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACSL4 acyl-CoA synthetase long-chain family member 4
AHNAK2 AHNAK nucleoprotein 2
AMT aminomethyltransferase
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAT1 alpha tubulin acetyltransferase 1
BAX BCL2-associated X protein
C10ORF88 chromosome 10 open reading frame 88
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CALML5 calmodulin-like 5
CAMK1 calcium/calmodulin-dependent protein kinase I
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CCDC64 coiled-coil domain containing 64
CCDC69 coiled-coil domain containing 69
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDHR2 cadherin-related family member 2
CHKB choline kinase beta
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN1 claudin 1
CLSTN2 calsyntenin 2
CNTN1 contactin 1
CORO7 coronin 7
CTSF cathepsin F
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EDAR ectodysplasin A receptor
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ETAA1 Ewing tumor-associated antigen 1
EXOC6B exocyst complex component 6B
F2R coagulation factor II (thrombin) receptor
FAM120C family with sequence similarity 120C
FAM169A family with sequence similarity 169, member A
GADD45G growth arrest and DNA-damage-inducible, gamma
GDAP1 ganglioside induced differentiation associated protein 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
HIST1H4C histone cluster 1, H4c
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KPNA5 karyopherin alpha 5 (importin alpha 6)
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
MDM4 MDM4, p53 regulator
MMP9 matrix metallopeptidase 9
MRPL41 mitochondrial ribosomal protein L41
MTA2 metastasis associated 1 family, member 2
MX2 MX dynamin-like GTPase 2
NEUROD1 neuronal differentiation 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPY4R neuropeptide Y receptor Y4
PCDHA6 protocadherin alpha 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PORCN porcupine homolog (Drosophila)
PYCRL pyrroline-5-carboxylate reductase-like
RAB36 RAB36, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RNF39 ring finger protein 39
RORC RAR-related orphan receptor C
RPL10L ribosomal protein L10-like
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC38A10 solute carrier family 38, member 10
SPINK4 serine peptidase inhibitor, Kazal type 4
STX1A syntaxin 1A (brain)
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPSG1 tryptase gamma 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSPYL2 TSPY-like 2
USP20 ubiquitin specific peptidase 20
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB48 zinc finger and BTB domain containing 48
ZNF492 zinc finger protein 492
ZNF747 zinc finger protein 747
ZNF750 zinc finger protein 750
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZNF816 zinc finger protein 816