etidronic acid-2985 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etidronic acid-2985 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADIRF adipogenesis regulatory factor
AFF3 AF4/FMR2 family, member 3
AMPH amphiphysin
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
AURKA aurora kinase A
BCL2L1 BCL2-like 1
BMP6 bone morphogenetic protein 6
C4BPA complement component 4 binding protein, alpha
CALD1 caldesmon 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD58 CD58 molecule
CD7 CD7 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFHR4 complement factor H-related 4
CHMP6 charged multivesicular body protein 6
CHN2 chimerin 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
CSH2 chorionic somatomammotropin hormone 2
CSNK1G1 casein kinase 1, gamma 1
CUL3 cullin 3
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGCR8 DGCR8 microprocessor complex subunit
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EN1 engrailed homeobox 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ETV2 ets variant 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
FMO5 flavin containing monooxygenase 5
FSD1 fibronectin type III and SPRY domain containing 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GTPBP1 GTP binding protein 1
GZMM granzyme M (lymphocyte met-ase 1)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB1 homeobox B1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL19 interleukin 19
INCENP inner centromere protein antigens 135/155kDa
KALRN kalirin, RhoGEF kinase
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LPAR1 lysophosphatidic acid receptor 1
MERTK MER proto-oncogene, tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MUC1 mucin 1, cell surface associated
NCOR2 nuclear receptor corepressor 2
NMT1 N-myristoyltransferase 1
NRCAM neuronal cell adhesion molecule
OCM2 oncomodulin 2
ONECUT2 one cut homeobox 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PBX2 pre-B-cell leukemia homeobox 2
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PODXL2 podocalyxin-like 2
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POU2F2 POU class 2 homeobox 2
POU5F1B POU class 5 homeobox 1B
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRLR prolactin receptor
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAP1GAP RAP1 GTPase activating protein
RAP2B RAP2B, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIF1 replication timing regulatory factor 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL7 ribosomal protein L7
SEMG2 semenogelin II
SH2D1A SH2 domain containing 1A
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A8 solute carrier family 12, member 8
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPON1 spondin 1, extracellular matrix protein
SSPN sarcospan
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STOML1 stomatin (EPB72)-like 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TECPR2 tectonin beta-propeller repeat containing 2
TEX13A testis expressed 13A
TEX41 testis expressed 41 (non-protein coding)
TMEM144 transmembrane protein 144
TMLHE trimethyllysine hydroxylase, epsilon
TNPO2 transportin 2
TRIM14 tripartite motif containing 14
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
WISP3 WNT1 inducible signaling pathway protein 3
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACP6 acid phosphatase 6, lysophosphatidic
AHDC1 AT hook, DNA binding motif, containing 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
C1ORF159 chromosome 1 open reading frame 159
C8A complement component 8, alpha polypeptide
CA5BP1 carbonic anhydrase VB pseudogene 1
CABP2 calcium binding protein 2
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CARD9 caspase recruitment domain family, member 9
CBY1 chibby homolog 1 (Drosophila)
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CELP carboxyl ester lipase pseudogene
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CNN1 calponin 1, basic, smooth muscle
CNPY4 canopy FGF signaling regulator 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTAGE9 CTAGE family, member 9
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ETAA1 Ewing tumor-associated antigen 1
ETV4 ets variant 4
FBXL2 F-box and leucine-rich repeat protein 2
FBXO40 F-box protein 40
FHOD1 formin homology 2 domain containing 1
GBP2 guanylate binding protein 2, interferon-inducible
GPR35 G protein-coupled receptor 35
GRIP2 glutamate receptor interacting protein 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HOXA5 homeobox A5
HOXC10 homeobox C10
HYAL2 hyaluronoglucosaminidase 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
JAM3 junctional adhesion molecule 3
JMJD4 jumonji domain containing 4
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLK11 kallikrein-related peptidase 11
LINC00260 long intergenic non-protein coding RNA 260
LPPR1 lipid phosphate phosphatase-related protein type 1
LTA lymphotoxin alpha
LYPLA2P1 lysophospholipase II pseudogene 1
MAGEH1 melanoma antigen family H1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPFFR1 neuropeptide FF receptor 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PCBP4 poly(rC) binding protein 4
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRDM12 PR domain containing 12
PRO2964 uncharacterized protein PRO2964
PRR7 proline rich 7 (synaptic)
PTDSS2 phosphatidylserine synthase 2
PYGB phosphorylase, glycogen; brain
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFPL1S RFPL1 antisense RNA 1
RWDD2A RWD domain containing 2A
SCN5A sodium channel, voltage gated, type V alpha subunit
SCRT1 scratch family zinc finger 1
SFRP5 secreted frizzled-related protein 5
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC10A3 solute carrier family 10, member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMR3A submaxillary gland androgen regulated protein 3A
SNAI1 snail family zinc finger 1
SYNDIG1 synapse differentiation inducing 1
TCHH trichohyalin
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP3 transcription factor Dp family, member 3
TNNT1 troponin T type 1 (skeletal, slow)
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
USP36 ubiquitin specific peptidase 36
VILL villin-like
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF10 zinc finger protein 10
ZNF280A zinc finger protein 280A
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF385D zinc finger protein 385D
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747