ethoxyquin-4321 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ethoxyquin-4321 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACPP acid phosphatase, prostate
ADAM17 ADAM metallopeptidase domain 17
ADCY1 adenylate cyclase 1 (brain)
AHCYL1 adenosylhomocysteinase-like 1
AK5 adenylate kinase 5
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BTG3 BTG family, member 3
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD177 CD177 molecule
CD58 CD58 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLEC3B C-type lectin domain family 3, member B
CLUAP1 clusterin associated protein 1
COMT catechol-O-methyltransferase
CTIF CBP80/20-dependent translation initiation factor
CYTH4 cytohesin 4
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DMBT1 deleted in malignant brain tumors 1
DMXL2 Dmx-like 2
DTNA dystrobrevin, alpha
EDN1 endothelin 1
EFNA1 ephrin-A1
EMID1 EMI domain containing 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM214B family with sequence similarity 214, member B
FLOT1 flotillin 1
FLT1 fms-related tyrosine kinase 1
FUBP1 far upstream element (FUSE) binding protein 1
GGT1 gamma-glutamyltransferase 1
GPR17 G protein-coupled receptor 17
GREM1 gremlin 1, DAN family BMP antagonist
GSTTP1 glutathione S-transferase theta pseudogene 1
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HMOX1 heme oxygenase 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IL5RA interleukin 5 receptor, alpha
ITGA7 integrin, alpha 7
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KIDINS220 kinase D-interacting substrate, 220kDa
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KMT2A lysine (K)-specific methyltransferase 2A
LTC4S leukotriene C4 synthase
MECOM MDS1 and EVI1 complex locus
MED25 mediator complex subunit 25
MEF2D myocyte enhancer factor 2D
MVB12B multivesicular body subunit 12B
MYF5 myogenic factor 5
MZF1 myeloid zinc finger 1
N4BP2L1 NEDD4 binding protein 2-like 1
NCOA3 nuclear receptor coactivator 3
NPR2 natriuretic peptide receptor 2
NPTX2 neuronal pentraxin II
NRP1 neuropilin 1
NYNRIN NYN domain and retroviral integrase containing
OLFML2B olfactomedin-like 2B
OPRL1 opiate receptor-like 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PASK PAS domain containing serine/threonine kinase
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PICALM phosphatidylinositol binding clathrin assembly protein
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRR protein tyrosine phosphatase, receptor type, R
RAB40AL RAB40A, member RAS oncogene family-like
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RGS12 regulator of G-protein signaling 12
RGS4 regulator of G-protein signaling 4
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF122 ring finger protein 122
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SIRPA signal-regulatory protein alpha
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SYCE1L synaptonemal complex central element protein 1-like
SYT17 synaptotagmin XVII
TBC1D30 TBC1 domain family, member 30
TBC1D5 TBC1 domain family, member 5
TGFBR1 transforming growth factor, beta receptor 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMC6 transmembrane channel-like 6
TNPO2 transportin 2
TNS4 tensin 4
TRD T cell receptor delta locus
TRIM3 tripartite motif containing 3
TSPAN7 tetraspanin 7
TTC9 tetratricopeptide repeat domain 9
VILL villin-like
XYLB xylulokinase homolog (H. influenzae)
ZC3H13 zinc finger CCCH-type containing 13
ZFP64 ZFP64 zinc finger protein
ZNF549 zinc finger protein 549
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ALPK1 alpha-kinase 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD36 ankyrin repeat domain 36
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BEX1 brain expressed, X-linked 1
C1ORF54 chromosome 1 open reading frame 54
C1ORF56 chromosome 1 open reading frame 56
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3 complement component 3
CCDC106 coiled-coil domain containing 106
CCDC177 coiled-coil domain containing 177
CD101 CD101 molecule
CINP cyclin-dependent kinase 2 interacting protein
CRMP1 collapsin response mediator protein 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLL3 delta-like 3 (Drosophila)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ESRRG estrogen-related receptor gamma
FAM169A family with sequence similarity 169, member A
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FZD10 frizzled class receptor 10
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4C histone cluster 1, H4c
HIST2H2AA3 histone cluster 2, H2aa3
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IL24 interleukin 24
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIAA1551 KIAA1551
KIRREL kin of IRRE like (Drosophila)
LIMS2 LIM and senescent cell antigen-like domains 2
LRP2 low density lipoprotein receptor-related protein 2
MDM4 MDM4, p53 regulator
MFSD11 major facilitator superfamily domain containing 11
MIS18BP1 MIS18 binding protein 1
MTERF4 mitochondrial transcription termination factor 4
MYO1F myosin IF
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NKX3-2 NK3 homeobox 2
NME5 NME/NM23 family member 5
OSBP2 oxysterol binding protein 2
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PAQR5 progestin and adipoQ receptor family member V
PCDHA9 protocadherin alpha 9
PDE5A phosphodiesterase 5A, cGMP-specific
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PODXL2 podocalyxin-like 2
PRF1 perforin 1 (pore forming protein)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR14L proline rich 14-like
PTPRS protein tyrosine phosphatase, receptor type, S
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFPL1S RFPL1 antisense RNA 1
RSRC1 arginine/serine-rich coiled-coil 1
SFXN1 sideroflexin 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLN sarcolipin
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBXAS1 thromboxane A synthase 1 (platelet)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIPRL TOR signaling pathway regulator
TLN1 talin 1
TMEM209 transmembrane protein 209
TUBA4B tubulin, alpha 4b
VEGFB vascular endothelial growth factor B
VN1R1 vomeronasal 1 receptor 1
WDR43 WD repeat domain 43
XYLT2 xylosyltransferase II
ZBTB38 zinc finger and BTB domain containing 38
ZNF492 zinc finger protein 492
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF721 zinc finger protein 721
ZNF749 zinc finger protein 749