ethotoin-4366 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the ethotoin-4366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADCK4 aarF domain containing kinase 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARSA arylsulfatase A
B9D1 B9 protein domain 1
BST2 bone marrow stromal cell antigen 2
BTN3A1 butyrophilin, subfamily 3, member A1
C19ORF66 chromosome 19 open reading frame 66
C19ORF73 chromosome 19 open reading frame 73
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCKAR cholecystokinin A receptor
CD58 CD58 molecule
CEP41 centrosomal protein 41kDa
CLEC4M C-type lectin domain family 4, member M
CLTA clathrin, light chain A
COL4A1 collagen, type IV, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYB5A cytochrome b5 type A (microsomal)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGCR2 DiGeorge syndrome critical region gene 2
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
ETNPPL ethanolamine-phosphate phospho-lyase
FAM182B family with sequence similarity 182, member B
FBXL18 F-box and leucine-rich repeat protein 18
FBXL7 F-box and leucine-rich repeat protein 7
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLRT2 fibronectin leucine rich transmembrane protein 2
GFAP glial fibrillary acidic protein
GJA4 gap junction protein, alpha 4, 37kDa
GJA8 gap junction protein, alpha 8, 50kDa
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HNF1B HNF1 homeobox B
HOXB3 homeobox B3
HRH3 histamine receptor H3
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGFBP7 insulin-like growth factor binding protein 7
IGLJ3 immunoglobulin lambda joining 3
IVL involucrin
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA0754 KIAA0754
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLK13 kallikrein-related peptidase 13
LINC00574 long intergenic non-protein coding RNA 574
LMNB1 lamin B1
LSP1 lymphocyte-specific protein 1
MLXIP MLX interacting protein
MMP25 matrix metallopeptidase 25
MORN1 MORN repeat containing 1
MTSS1 metastasis suppressor 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PAX8 paired box 8
PDE10A phosphodiesterase 10A
PDX1 pancreatic and duodenal homeobox 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLXNC1 plexin C1
POPDC3 popeye domain containing 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCI protein kinase C, iota
PRLH prolactin releasing hormone
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RDH16 retinol dehydrogenase 16 (all-trans)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHAG Rh-associated glycoprotein
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SCG2 secretogranin II
SFRP4 secreted frizzled-related protein 4
SGK2 serum/glucocorticoid regulated kinase 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
STATH statherin
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYP synaptophysin
SYT11 synaptotagmin XI
TCF4 transcription factor 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TP53I11 tumor protein p53 inducible protein 11
TPP1 tripeptidyl peptidase I
TRAF1 TNF receptor-associated factor 1
TRO trophinin
ZC3H13 zinc finger CCCH-type containing 13
ZFP64 ZFP64 zinc finger protein
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADM adrenomedullin
ALPK1 alpha-kinase 1
ARHGAP4 Rho GTPase activating protein 4
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARR3 arrestin 3, retinal (X-arrestin)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C1ORF21 chromosome 1 open reading frame 21
C2ORF27A chromosome 2 open reading frame 27A
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CD79B CD79b molecule, immunoglobulin-associated beta
CEL carboxyl ester lipase
CFHR4 complement factor H-related 4
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CNTFR ciliary neurotrophic factor receptor
CUEDC1 CUE domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DNASE1L2 deoxyribonuclease I-like 2
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
FGF13 fibroblast growth factor 13
FSHB follicle stimulating hormone, beta polypeptide
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR1 G protein-coupled receptor 1
GSTP1 glutathione S-transferase pi 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC5 histone deacetylase 5
HIST1H2AK histone cluster 1, H2ak
HIST1H2BM histone cluster 1, H2bm
HIST1H2BO histone cluster 1, H2bo
HOXC8 homeobox C8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITM2C integral membrane protein 2C
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KIF13B kinesin family member 13B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LGALS9 lectin, galactoside-binding, soluble, 9
LHX1 LIM homeobox 1
LIG4 ligase IV, DNA, ATP-dependent
LOC157562 uncharacterized LOC157562
LRRTM2 leucine rich repeat transmembrane neuronal 2
LTBP2 latent transforming growth factor beta binding protein 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PGBD5 piggyBac transposable element derived 5
PICK1 protein interacting with PRKCA 1
PLA2G15 phospholipase A2, group XV
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RAB30 RAB30, member RAS oncogene family
RECQL4 RecQ protein-like 4
RLN1 relaxin 1
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RPGR retinitis pigmentosa GTPase regulator
RPL10L ribosomal protein L10-like
SCARA3 scavenger receptor class A, member 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERGEF secretion regulating guanine nucleotide exchange factor
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A9 solute carrier family 12, member 9
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLPI secretory leukocyte peptidase inhibitor
SPTBN2 spectrin, beta, non-erythrocytic 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
STIM1 stromal interaction molecule 1
TBC1D2 TBC1 domain family, member 2
TCEAL2 transcription elongation factor A (SII)-like 2
TM4SF4 transmembrane 4 L six family member 4
TM4SF5 transmembrane 4 L six family member 5
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPSG1 tryptase gamma 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM68 tripartite motif containing 68
TSNAXIP1 translin-associated factor X interacting protein 1
UPK2 uroplakin 2
USP19 ubiquitin specific peptidase 19
VIM vimentin
XAB2 XPA binding protein 2
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF286A zinc finger protein 286A
ZNF41 zinc finger protein 41
ZNF747 zinc finger protein 747