ethosuximide-7308 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ethosuximide-7308 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSS3 acyl-CoA synthetase short-chain family member 3
AIM1L absent in melanoma 1-like
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARHGAP10 Rho GTPase activating protein 10
ARL15 ADP-ribosylation factor-like 15
ATAD5 ATPase family, AAA domain containing 5
ATXN2L ataxin 2-like
AURKA aurora kinase A
BCR breakpoint cluster region
BICD1 bicaudal D homolog 1 (Drosophila)
C16ORF59 chromosome 16 open reading frame 59
C2ORF68 chromosome 2 open reading frame 68
CA12 carbonic anhydrase XII
CA5B carbonic anhydrase VB, mitochondrial
CAV2 caveolin 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
COL5A1 collagen, type V, alpha 1
CPQ carboxypeptidase Q
CRTC1 CREB regulated transcription coactivator 1
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CTNND2 catenin (cadherin-associated protein), delta 2
DAGLA diacylglycerol lipase, alpha
DPF1 D4, zinc and double PHD fingers family 1
DPYSL3 dihydropyrimidinase-like 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EML3 echinoderm microtubule associated protein like 3
ETV6 ets variant 6
FAS Fas cell surface death receptor
FBXO46 F-box protein 46
FCMR Fc fragment of IgM receptor
FN1 fibronectin 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GOLGA8A golgin A8 family, member A
GPR107 G protein-coupled receptor 107
HDGFRP3 hepatoma-derived growth factor, related protein 3
ICOSLG inducible T-cell co-stimulator ligand
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IL24 interleukin 24
IPO8 importin 8
KCTD13 potassium channel tetramerization domain containing 13
LRRK1 leucine-rich repeat kinase 1
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MFAP3 microfibrillar-associated protein 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEK9 NIMA-related kinase 9
NINJ1 ninjurin 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PRB4 proline-rich protein BstNI subfamily 4
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
QKI QKI, KH domain containing, RNA binding
QSER1 glutamine and serine rich 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB31 RAB31, member RAS oncogene family
RARG retinoic acid receptor, gamma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN3 Ras and Rab interactor 3
RPGRIP1L RPGRIP1-like
RPL5 ribosomal protein L5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SCN1B sodium channel, voltage gated, type I beta subunit
SENP6 SUMO1/sentrin specific peptidase 6
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERTAD3 SERTA domain containing 3
SETDB1 SET domain, bifurcated 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAC SH3 and cysteine rich domain
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TADA3 transcriptional adaptor 3
TAT tyrosine aminotransferase
TBC1D30 TBC1 domain family, member 30
TCP11 t-complex 11, testis-specific
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM180 transmembrane protein 180
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TUSC3 tumor suppressor candidate 3
UNC45A unc-45 homolog A (C. elegans)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB7A zinc finger and BTB domain containing 7A
ZHX3 zinc fingers and homeoboxes 3
ZNF219 zinc finger protein 219
ZNF286A zinc finger protein 286A
ZNF287 zinc finger protein 287
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADGRF1 adhesion G protein-coupled receptor F1
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARMCX2 armadillo repeat containing, X-linked 2
ASTE1 asteroid homolog 1 (Drosophila)
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C1QTNF1 C1q and tumor necrosis factor related protein 1
C6ORF47 chromosome 6 open reading frame 47
C9ORF91 chromosome 9 open reading frame 91
CA5BP1 carbonic anhydrase VB pseudogene 1
CASZ1 castor zinc finger 1
CBY1 chibby homolog 1 (Drosophila)
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CDON cell adhesion associated, oncogene regulated
CLK3 CDC-like kinase 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CRYL1 crystallin, lambda 1
CUL9 cullin 9
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DET1 de-etiolated homolog 1 (Arabidopsis)
DGAT1 diacylglycerol O-acyltransferase 1
DGKZ diacylglycerol kinase, zeta
DLK1 delta-like 1 homolog (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
EPHX2 epoxide hydrolase 2, cytoplasmic
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FAM131B family with sequence similarity 131, member B
FAM160B2 family with sequence similarity 160, member B2
FANCF Fanconi anemia, complementation group F
FHOD1 formin homology 2 domain containing 1
FUZ fuzzy planar cell polarity protein
GAREM GRB2 associated, regulator of MAPK1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GMIP GEM interacting protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HOMER2 homer scaffolding protein 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
ITPKC inositol-trisphosphate 3-kinase C
KIAA1549L KIAA1549-like
KLF2 Kruppel-like factor 2
MANBA mannosidase, beta A, lysosomal
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL2 mitochondrial ribosomal protein L2
MX1 MX dynamin-like GTPase 1
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NTSR1 neurotensin receptor 1 (high affinity)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP16 poly (ADP-ribose) polymerase family, member 16
PC pyruvate carboxylase
PCOLCE procollagen C-endopeptidase enhancer
PLAC1 placenta-specific 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRR14L proline rich 14-like
PRR3 proline rich 3
RAB17 RAB17, member RAS oncogene family
REEP4 receptor accessory protein 4
RGS17 regulator of G-protein signaling 17
SALL2 spalt-like transcription factor 2
SCARA3 scavenger receptor class A, member 3
SCD5 stearoyl-CoA desaturase 5
SESN1 sestrin 1
SETBP1 SET binding protein 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP140L SP140 nuclear body protein-like
STAR steroidogenic acute regulatory protein
STARD13 StAR-related lipid transfer (START) domain containing 13
STBD1 starch binding domain 1
STK25 serine/threonine kinase 25
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D19 TBC1 domain family, member 19
TMEM156 transmembrane protein 156
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
USP20 ubiquitin specific peptidase 20
XYLT2 xylosyltransferase II
ZFP36 ZFP36 ring finger protein
ZNF227 zinc finger protein 227
ZNF273 zinc finger protein 273
ZNF358 zinc finger protein 358
ZNF668 zinc finger protein 668