ethaverine-3375 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ethaverine-3375 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRA2 adhesion G protein-coupled receptor A2
AGMAT agmatine ureohydrolase (agmatinase)
AJAP1 adherens junctions associated protein 1
AMPH amphiphysin
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARC activity-regulated cytoskeleton-associated protein
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARTN artemin
ATG10 autophagy related 10
ATP10A ATPase, class V, type 10A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BDKRB2 bradykinin receptor B2
BMP1 bone morphogenetic protein 1
C1ORF61 chromosome 1 open reading frame 61
C1ORF68 chromosome 1 open reading frame 68
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD47 CD47 molecule
CDH8 cadherin 8, type 2
CEP41 centrosomal protein 41kDa
CLCA1 chloride channel accessory 1
COL19A1 collagen, type XIX, alpha 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DLL3 delta-like 3 (Drosophila)
DOCK6 dedicator of cytokinesis 6
DPF1 D4, zinc and double PHD fingers family 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EML2 echinoderm microtubule associated protein like 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC2 excision repair cross-complementation group 2
FBN1 fibrillin 1
FHL1 four and a half LIM domains 1
FRMD1 FERM domain containing 1
FYB FYN binding protein
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAS2L1 growth arrest-specific 2 like 1
GPER1 G protein-coupled estrogen receptor 1
GSTM5 glutathione S-transferase mu 5
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IL23A interleukin 23, alpha subunit p19
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LARP4B La ribonucleoprotein domain family, member 4B
LARP6 La ribonucleoprotein domain family, member 6
LMNA lamin A/C
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MEF2C myocyte enhancer factor 2C
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPL MPL proto-oncogene, thrombopoietin receptor
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NPR2 natriuretic peptide receptor 2
NUP88 nucleoporin 88kDa
PAX9 paired box 9
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCLO piccolo presynaptic cytomatrix protein
PDE9A phosphodiesterase 9A
PEG10 paternally expressed 10
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP5C protein phosphatase 5, catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG4 pregnancy specific beta-1-glycoprotein 4
PTK2B protein tyrosine kinase 2 beta
PWAR5 Prader Willi/Angelman region RNA 5
RABGAP1L RAB GTPase activating protein 1-like
RASIP1 Ras interacting protein 1
RBM17 RNA binding motif protein 17
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPH3A rabphilin 3A
RPL35A ribosomal protein L35a
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLIT1 slit homolog 1 (Drosophila)
SLN sarcolipin
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STS steroid sulfatase (microsomal), isozyme S
SULT4A1 sulfotransferase family 4A, member 1
TEF thyrotrophic embryonic factor
TM4SF1 transmembrane 4 L six family member 1
TPMT thiopurine S-methyltransferase
TYRO3 TYRO3 protein tyrosine kinase
WTAP Wilms tumor 1 associated protein
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XAF1 XIAP associated factor 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARPIN actin-related protein 2/3 complex inhibitor
ATAT1 alpha tubulin acetyltransferase 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AXIN1 axin 1
BCAS1 breast carcinoma amplified sequence 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
C14ORF93 chromosome 14 open reading frame 93
C3 complement component 3
C6ORF47 chromosome 6 open reading frame 47
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC94 coiled-coil domain containing 94
CDKL3 cyclin-dependent kinase-like 3
CFD complement factor D (adipsin)
CGA glycoprotein hormones, alpha polypeptide
CIC capicua transcriptional repressor
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CTNNBIP1 catenin, beta interacting protein 1
DBF4B DBF4 zinc finger B
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM3 dynamin 3
DPY19L1P1 DPY19L1 pseudogene 1
DSC2 desmocollin 2
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ETNK2 ethanolamine kinase 2
FBXO2 F-box protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GEMIN8 gem (nuclear organelle) associated protein 8
GMPR guanosine monophosphate reductase
GPR143 G protein-coupled receptor 143
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HOXC8 homeobox C8
HPX hemopexin
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK5 potassium channel, two pore domain subfamily K, member 5
KREMEN2 kringle containing transmembrane protein 2
MAPK10 mitogen-activated protein kinase 10
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
NOL12 nucleolar protein 12
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
NYNRIN NYN domain and retroviral integrase containing
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PDIA3 protein disulfide isomerase family A, member 3
PEX26 peroxisomal biogenesis factor 26
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMEL premelanosome protein
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RCAN3 RCAN family member 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL10L ribosomal protein L10-like
SCUBE2 signal peptide, CUB domain, EGF-like 2
SFXN1 sideroflexin 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SREK1IP1 SREK1-interacting protein 1
TCTN2 tectonic family member 2
TEP1 telomerase-associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TMEM242 transmembrane protein 242
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TRIM36 tripartite motif containing 36
TRIM5 tripartite motif containing 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VGF VGF nerve growth factor inducible
XAB2 XPA binding protein 2
ZFHX4 zinc finger homeobox 4
ZNF211 zinc finger protein 211
ZNF862 zinc finger protein 862