etamivan-7021 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etamivan-7021 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM23 ADAM metallopeptidase domain 23
ADCK2 aarF domain containing kinase 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOE apolipoprotein E
BRD4 bromodomain containing 4
C10ORF95 chromosome 10 open reading frame 95
C1ORF21 chromosome 1 open reading frame 21
C7ORF43 chromosome 7 open reading frame 43
CBX8 chromobox homolog 8
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CEP162 centrosomal protein 162kDa
CLASP2 cytoplasmic linker associated protein 2
CLCN4 chloride channel, voltage-sensitive 4
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DESI2 desumoylating isopeptidase 2
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM65A family with sequence similarity 65, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GPR45 G protein-coupled receptor 45
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HOXC8 homeobox C8
HPS1 Hermansky-Pudlak syndrome 1
IL1RN interleukin 1 receptor antagonist
IPO8 importin 8
KIAA0141 KIAA0141
KIAA0195 KIAA0195
KITLG KIT ligand
KRT19P2 keratin 19 pseudogene 2
LPPR2 lipid phosphate phosphatase-related protein type 2
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LZTR1 leucine-zipper-like transcription regulator 1
MED15 mediator complex subunit 15
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MKL1 megakaryoblastic leukemia (translocation) 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPS12 mitochondrial ribosomal protein S12
MTERF4 mitochondrial transcription termination factor 4
MYBPC3 myosin binding protein C, cardiac
N4BP2L2 NEDD4 binding protein 2-like 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF2 neurofibromin 2 (merlin)
NFX1 nuclear transcription factor, X-box binding 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAOX polyamine oxidase (exo-N4-amino)
PASK PAS domain containing serine/threonine kinase
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX5 peroxisomal biogenesis factor 5
PHF20L1 PHD finger protein 20-like 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCH1 phospholipase C, eta 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRDM2 PR domain containing 2, with ZNF domain
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RGS12 regulator of G-protein signaling 12
RRBP1 ribosome binding protein 1
RUFY3 RUN and FYVE domain containing 3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SASH1 SAM and SH3 domain containing 1
SHANK1 SH3 and multiple ankyrin repeat domains 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SPATA1 spermatogenesis associated 1
SSX3 synovial sarcoma, X breakpoint 3
SYNJ2 synaptojanin 2
TBCD tubulin folding cofactor D
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TH tyrosine hydroxylase
TUBGCP5 tubulin, gamma complex associated protein 5
UBE3A ubiquitin protein ligase E3A
UNC119 unc-119 homolog (C. elegans)
UTRN utrophin
VAC14 Vac14 homolog (S. cerevisiae)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
WIZ widely interspaced zinc finger motifs
ZBTB14 zinc finger and BTB domain containing 14
ZNF446 zinc finger protein 446
ZNF492 zinc finger protein 492
ZNF609 zinc finger protein 609
ZNF74 zinc finger protein 74
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKIP1 A kinase (PRKA) interacting protein 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATP13A2 ATPase type 13A2
AUP1 ancient ubiquitous protein 1
BAK1 BCL2-antagonist/killer 1
BCOR BCL6 corepressor
BCORL1 BCL6 corepressor-like 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF56 chromosome 1 open reading frame 56
C5 complement component 5
CALCOCO1 calcium binding and coiled-coil domain 1
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CEP85 centrosomal protein 85kDa
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CIDEC cell death-inducing DFFA-like effector c
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
COCH cochlin
CUEDC1 CUE domain containing 1
DENND4C DENN/MADD domain containing 4C
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSCAM Down syndrome cell adhesion molecule
DUSP5 dual specificity phosphatase 5
EFNA3 ephrin-A3
EXTL2 exostosin-like glycosyltransferase 2
FKBP5 FK506 binding protein 5
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GDAP2 ganglioside induced differentiation associated protein 2
GLCE glucuronic acid epimerase
GMPPA GDP-mannose pyrophosphorylase A
H2AFY2 H2A histone family, member Y2
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
ICK intestinal cell (MAK-like) kinase
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD20 potassium channel tetramerization domain containing 20
LINS lines homolog (Drosophila)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC49 leucine rich repeat containing 49
MAGEF1 melanoma antigen family F1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MMP9 matrix metallopeptidase 9
MT1HL1 metallothionein 1H-like 1
MTA2 metastasis associated 1 family, member 2
MTCL1 microtubule crosslinking factor 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NSD1 nuclear receptor binding SET domain protein 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA6 protocadherin alpha 6
PDLIM2 PDZ and LIM domain 2 (mystique)
PGM1 phosphoglucomutase 1
PGP phosphoglycolate phosphatase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PRKX protein kinase, X-linked
PTPN9 protein tyrosine phosphatase, non-receptor type 9
QTRT1 queuine tRNA-ribosyltransferase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIBC2 RIB43A domain with coiled-coils 2
RNF123 ring finger protein 123
RNF31 ring finger protein 31
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUFY2 RUN and FYVE domain containing 2
SCAMP5 secretory carrier membrane protein 5
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIRT2 sirtuin 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A8 solute carrier family 12, member 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPINK4 serine peptidase inhibitor, Kazal type 4
STXBP2 syntaxin binding protein 2
TBC1D12 TBC1 domain family, member 12
TCTA T-cell leukemia translocation altered
THBS3 thrombospondin 3
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ULBP2 UL16 binding protein 2
VWA9 von Willebrand factor A domain containing 9
WBP2 WW domain binding protein 2
ZC3H3 zinc finger CCCH-type containing 3
ZNF586 zinc finger protein 586
ZNF668 zinc finger protein 668