estrogen-receptor positive breast cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

158 genes co-occuring with the disease estrogen-receptor positive breast cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ESR1 estrogen receptor 1 2.2516
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 1.38821
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.37643
FBXL3 F-box and leucine-rich repeat protein 3 1.23126
GPR152 G protein-coupled receptor 152 1.22649
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 1.19877
SLMO2 slowmo homolog 2 (Drosophila) 1.19877
PGR progesterone receptor 1.17851
RAB31 RAB31, member RAS oncogene family 1.15752
SLC39A7 solute carrier family 39 (zinc transporter), member 7 1.11351
TMEM14A transmembrane protein 14A 1.10048
ERBB2 erb-b2 receptor tyrosine kinase 2 1.09125
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 1.0732
YPEL3 yippee-like 3 (Drosophila) 1.06102
HOXB13 homeobox B13 1.03114
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.02608
DHRS4 dehydrogenase/reductase (SDR family) member 4 1.0071
TRAM2 translocation associated membrane protein 2 0.983479
NCKAP1 NCK-associated protein 1 0.918848
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.911022
CCND1 cyclin D1 0.906086
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.856087
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.837656
CUEDC2 CUE domain containing 2 0.832738
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.797872
SPHK1 sphingosine kinase 1 0.766759
MREG melanoregulin 0.765127
EGFR epidermal growth factor receptor 0.759416
FGFR2 fibroblast growth factor receptor 2 0.74883
TFF1 trefoil factor 1 0.74883
RNF146 ring finger protein 146 0.733406
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.733406
STS steroid sulfatase (microsomal), isozyme S 0.728952
PEF1 penta-EF-hand domain containing 1 0.718846
CENPA centromere protein A 0.705144
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.692697
CTSD cathepsin D 0.689893
PXT1 peroxisomal, testis specific 1 0.67551
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 0.65288
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.644192
SAFB scaffold attachment factor B 0.635135
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.632777
FKBP8 FK506 binding protein 8, 38kDa 0.630027
PTPRR protein tyrosine phosphatase, receptor type, R 0.629242
IGF1 insulin-like growth factor 1 (somatomedin C) 0.619834
PSG5 pregnancy specific beta-1-glycoprotein 5 0.617877
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.617094
IGF1R insulin-like growth factor 1 receptor 0.60108
GREB1 growth regulation by estrogen in breast cancer 1 0.595623
DUSP2 dual specificity phosphatase 2 0.591727
RAB18 RAB18, member RAS oncogene family 0.590948
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.581996
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.576939
HEATR6 HEAT repeat containing 6 0.575383
HSPB8 heat shock 22kDa protein 8 0.568386
KDM5B lysine (K)-specific demethylase 5B 0.562946
PRCP prolylcarboxypeptidase (angiotensinase C) 0.555956
NEU1 sialidase 1 (lysosomal sialidase) 0.554015
NUP88 nucleoporin 88kDa 0.550522
FOXA1 forkhead box A1 0.550134
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.545481
PDZK1 PDZ domain containing 1 0.543542
API5 apoptosis inhibitor 5 0.540055
CTSZ cathepsin Z 0.533475
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.526132
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.523045
TOX3 TOX high mobility group box family member 3 0.519575
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.512264
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.505739
STC2 stanniocalcin 2 0.504207
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.498085
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.490835
PRMT2 protein arginine methyltransferase 2 0.481705
FGF17 fibroblast growth factor 17 0.479047
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.477151
SIAH2 siah E3 ubiquitin protein ligase 2 0.469576
CHD1 chromodomain helicase DNA binding protein 1 0.468063
STAT5B signal transducer and activator of transcription 5B 0.461639
PNN pinin, desmosome associated protein 0.457109
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.456732
ESRRG estrogen-related receptor gamma 0.448064
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.446935
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.43753
TP53 tumor protein p53 0.429266
USP1 ubiquitin specific peptidase 1 0.424389
LUM lumican 0.418768
ELAVL1 ELAV like RNA binding protein 1 0.415398
WISP2 WNT1 inducible signaling pathway protein 2 0.409414
MIR26B microRNA 26b 0.398962
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.398216
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.394118
SHBG sex hormone-binding globulin 0.389653
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.387794
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.384822
DUSP5 dual specificity phosphatase 5 0.38111
IRF9 interferon regulatory factor 9 0.360026
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.353395
ESR2 estrogen receptor 2 (ER beta) 0.352659
BTG2 BTG family, member 2 0.352291
ZYX zyxin 0.347511
BCL2L1 BCL2-like 1 0.347144
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.347144
SMAD3 SMAD family member 3 0.346409
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.336144
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.333949
GSTO1 glutathione S-transferase omega 1 0.328469
S1PR3 sphingosine-1-phosphate receptor 3 0.326646
SET SET nuclear proto-oncogene 0.308842
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.30848
JUNB jun B proto-oncogene 0.30631
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.30342
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.301976
FBLN1 fibulin 1 0.301254
HRK harakiri, BCL2 interacting protein 0.294772
IGFBP3 insulin-like growth factor binding protein 3 0.293694
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.292257
EGLN2 egl-9 family hypoxia-inducible factor 2 0.290821
PDPK1 3-phosphoinositide dependent protein kinase 1 0.286519
BIK BCL2-interacting killer (apoptosis-inducing) 0.284013
MYB v-myb avian myeloblastosis viral oncogene homolog 0.28294
TGFB1 transforming growth factor, beta 1 0.278297
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.270108
HDAC1 histone deacetylase 1 0.265849
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.252774
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.248905
KIF11 kinesin family member 11 0.248203
GPER1 G protein-coupled estrogen receptor 1 0.244345
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.243995
NRG1 neuregulin 1 0.242245
AGR2 anterior gradient 2 0.237706
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.23666
HDAC6 histone deacetylase 6 0.234225
IGFBP6 insulin-like growth factor binding protein 6 0.226952
EGLN3 egl-9 family hypoxia-inducible factor 3 0.224196
CUL1 cullin 1 0.217012
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.214636
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.209918
MKI67 marker of proliferation Ki-67 0.207245
ARSH arylsulfatase family, member H 0.202946
GATA3 GATA binding protein 3 0.196139
TFF2 trefoil factor 2 0.196139
AURKA aurora kinase A 0.195183
ASPN asporin 0.194548
BAX BCL2-associated X protein 0.18621
B3GAT2 beta-1,3-glucuronyltransferase 2 0.184128
MAPK6 mitogen-activated protein kinase 6 0.177576
DAXX death-domain associated protein 0.175947
TSKU tsukushi, small leucine rich proteoglycan 0.171785
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.170789
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.170054
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.168381
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.168381
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.167452
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.165874
S100A7 S100 calcium binding protein A7 0.162707
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.159302
PEPD peptidase D 0.159124
MRPS30 mitochondrial ribosomal protein S30 0.157602