estriol-7220 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the estriol-7220 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AMACR alpha-methylacyl-CoA racemase
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATP10B ATPase, class V, type 10B
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BAX BCL2-associated X protein
BTBD7 BTB (POZ) domain containing 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CDRT1 CMT1A duplicated region transcript 1
CHM choroideremia (Rab escort protein 1)
CHML choroideremia-like (Rab escort protein 2)
COL14A1 collagen, type XIV, alpha 1
DCTN1 dynactin 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EGR3 early growth response 3
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
EVI2B ecotropic viral integration site 2B
FCMR Fc fragment of IgM receptor
FRMPD1 FERM and PDZ domain containing 1
FYB FYN binding protein
FZD10 frizzled class receptor 10
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GDAP1 ganglioside induced differentiation associated protein 1
GLIPR1 GLI pathogenesis-related 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNRHR gonadotropin-releasing hormone receptor
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNF1A HNF1 homeobox A
HRH2 histamine receptor H2
IDI2-AS1 IDI2 antisense RNA 1
INE1 inactivation escape 1 (non-protein coding)
JAM3 junctional adhesion molecule 3
KCNIP1 Kv channel interacting protein 1
KLF12 Kruppel-like factor 12
KRT19P2 keratin 19 pseudogene 2
KRT6B keratin 6B, type II
LAPTM5 lysosomal protein transmembrane 5
LIF leukemia inhibitory factor
LOXL3 lysyl oxidase-like 3
LRRC8B leucine rich repeat containing 8 family, member B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8 mitogen-activated protein kinase 8
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MNDA myeloid cell nuclear differentiation antigen
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRAS muscle RAS oncogene homolog
MSI1 musashi RNA-binding protein 1
MUSK muscle, skeletal, receptor tyrosine kinase
NFX1 nuclear transcription factor, X-box binding 1
NLE1 notchless homolog 1 (Drosophila)
NOX1 NADPH oxidase 1
OCA2 oculocutaneous albinism II
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAPPA2 pappalysin 2
PAX5 paired box 5
PCM1 pericentriolar material 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLK4 polo-like kinase 4
PRF1 perforin 1 (pore forming protein)
PRO2964 uncharacterized protein PRO2964
PRSS16 protease, serine, 16 (thymus)
PTCRA pre T-cell antigen receptor alpha
PTPRA protein tyrosine phosphatase, receptor type, A
RAB35 RAB35, member RAS oncogene family
RB1 retinoblastoma 1
RFXAP regulatory factor X-associated protein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCAPER S-phase cyclin A-associated protein in the ER
SCGB2A2 secretoglobin, family 2A, member 2
SERHL2 serine hydrolase-like 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SNX13 sorting nexin 13
SSX1 synovial sarcoma, X breakpoint 1
STK3 serine/threonine kinase 3
SYBU syntabulin (syntaxin-interacting)
TGM2 transglutaminase 2
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOP3A topoisomerase (DNA) III alpha
TRIB2 tribbles pseudokinase 2
UBE3A ubiquitin protein ligase E3A
UBOX5 U-box domain containing 5
VNN1 vanin 1
WSCD1 WSC domain containing 1
WWOX WW domain containing oxidoreductase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFY zinc finger protein, Y-linked
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF286A zinc finger protein 286A
ZNF41 zinc finger protein 41
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADCY6 adenylate cyclase 6
ADGRG6 adhesion G protein-coupled receptor G6
ALPK1 alpha-kinase 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD5 ATPase family, AAA domain containing 5
C17ORF70 chromosome 17 open reading frame 70
C3ORF52 chromosome 3 open reading frame 52
C7ORF43 chromosome 7 open reading frame 43
CCNT1 cyclin T1
CD302 CD302 molecule
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CLSTN1 calsyntenin 1
COBL cordon-bleu WH2 repeat protein
COL4A5 collagen, type IV, alpha 5
CRY1 cryptochrome circadian clock 1
CTNNBIP1 catenin, beta interacting protein 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAL4 dynein, axonemal, light chain 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
FBXL15 F-box and leucine-rich repeat protein 15
FHOD1 formin homology 2 domain containing 1
GAA glucosidase, alpha; acid
GATA6 GATA binding protein 6
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HMHA1 histocompatibility (minor) HA-1
HOXC13 homeobox C13
IL4R interleukin 4 receptor
IRX4 iroquois homeobox 4
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL36 kelch-like family member 36
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHFPL2 lipoma HMGIC fusion partner-like 2
LHX6 LIM homeobox 6
LOC730101 uncharacterized LOC730101
LRP3 low density lipoprotein receptor-related protein 3
LRP6 low density lipoprotein receptor-related protein 6
MAST3 microtubule associated serine/threonine kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MOSPD3 motile sperm domain containing 3
MYLIP myosin regulatory light chain interacting protein
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCS1 neuronal calcium sensor 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NKAIN1 Na+/K+ transporting ATPase interacting 1
NUPL2 nucleoporin like 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAQR6 progestin and adipoQ receptor family member VI
PILRB paired immunoglobin-like type 2 receptor beta
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKX protein kinase, X-linked
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS8 protease, serine, 8
PTPRU protein tyrosine phosphatase, receptor type, U
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB5B RAB5B, member RAS oncogene family
RANBP10 RAN binding protein 10
RBL1 retinoblastoma-like 1
RBM23 RNA binding motif protein 23
RECQL4 RecQ protein-like 4
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
ROM1 retinal outer segment membrane protein 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCD5 stearoyl-CoA desaturase 5
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A9 solute carrier family 12, member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SUGP1 SURP and G patch domain containing 1
TBC1D10B TBC1 domain family, member 10B
TCTA T-cell leukemia translocation altered
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TRAPPC11 trafficking protein particle complex 11
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
ZBTB6 zinc finger and BTB domain containing 6
ZDHHC18 zinc finger, DHHC-type containing 18
ZFHX3 zinc finger homeobox 3
ZMAT5 zinc finger, matrin-type 5
ZNF675 zinc finger protein 675