estradiol-4432 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the estradiol-4432 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADRA1D adrenoceptor alpha 1D
AIM1L absent in melanoma 1-like
ALDOB aldolase B, fructose-bisphosphate
ARTN artemin
ATG10 autophagy related 10
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATN1 atrophin 1
C10ORF10 chromosome 10 open reading frame 10
CALCA calcitonin-related polypeptide alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC57 coiled-coil domain containing 57
CCL20 chemokine (C-C motif) ligand 20
CCL27 chemokine (C-C motif) ligand 27
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDC14B cell division cycle 14B
CDHR2 cadherin-related family member 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC3B C-type lectin domain family 3, member B
CLTA clathrin, light chain A
COL3A1 collagen, type III, alpha 1
CORO2B coronin, actin binding protein, 2B
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGCR6L DiGeorge syndrome critical region gene 6-like
DICER1 dicer 1, ribonuclease type III
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP13 dual specificity phosphatase 13
E2F5 E2F transcription factor 5, p130-binding
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FKRP fukutin related protein
FLOT1 flotillin 1
FRMD8 FERM domain containing 8
GMPR guanosine monophosphate reductase
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HFE hemochromatosis
HNF4A hepatocyte nuclear factor 4, alpha
HSPG2 heparan sulfate proteoglycan 2
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KIF25 kinesin family member 25
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LDB2 LIM domain binding 2
LIPE lipase, hormone-sensitive
MAP2K7 mitogen-activated protein kinase kinase 7
MCF2L MCF.2 cell line derived transforming sequence-like
MEF2D myocyte enhancer factor 2D
MFSD7 major facilitator superfamily domain containing 7
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MYF5 myogenic factor 5
MYH2 myosin, heavy chain 2, skeletal muscle, adult
N4BP2L1 NEDD4 binding protein 2-like 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NCR2 natural cytotoxicity triggering receptor 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEU3 sialidase 3 (membrane sialidase)
NF1 neurofibromin 1
NMRK2 nicotinamide riboside kinase 2
NPVF neuropeptide VF precursor
NTF3 neurotrophin 3
OLIG2 oligodendrocyte lineage transcription factor 2
PCDHB3 protocadherin beta 3
PCDHGA10 protocadherin gamma subfamily A, 10
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE7B phosphodiesterase 7B
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PROL1 proline rich, lacrimal 1
RAB33A RAB33A, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RGCC regulator of cell cycle
RIMS1 regulating synaptic membrane exocytosis 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RUNDC3A RUN domain containing 3A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOCS7 suppressor of cytokine signaling 7
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAPBPL TAP binding protein-like
TGM4 transglutaminase 4
TK2 thymidine kinase 2, mitochondrial
TM4SF4 transmembrane 4 L six family member 4
TNS1 tensin 1
TPP1 tripeptidyl peptidase I
ULBP1 UL16 binding protein 1
VIPR2 vasoactive intestinal peptide receptor 2
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WDR78 WD repeat domain 78
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF334 zinc finger protein 334
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM23 ADAM metallopeptidase domain 23
AFF4 AF4/FMR2 family, member 4
AGMAT agmatine ureohydrolase (agmatinase)
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD36 ankyrin repeat domain 36
ARHGAP10 Rho GTPase activating protein 10
ARMC6 armadillo repeat containing 6
ATAD5 ATPase family, AAA domain containing 5
BMPR1B bone morphogenetic protein receptor, type IB
C17ORF53 chromosome 17 open reading frame 53
C8ORF44 chromosome 8 open reading frame 44
CCNO cyclin O
CD82 CD82 molecule
CDH7 cadherin 7, type 2
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CINP cyclin-dependent kinase 2 interacting protein
CIR1 corepressor interacting with RBPJ, 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL9A3 collagen, type IX, alpha 3
CORT cortistatin
DBF4B DBF4 zinc finger B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EHD3 EH-domain containing 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
ERCC5 excision repair cross-complementation group 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLB1L2 galactosidase, beta 1-like 2
GLCE glucuronic acid epimerase
GREB1L growth regulation by estrogen in breast cancer-like
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HDAC7 histone deacetylase 7
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HSPA1L heat shock 70kDa protein 1-like
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA14 interferon, alpha 14
IL7 interleukin 7
INO80D INO80 complex subunit D
KIAA0754 KIAA0754
KLHL28 kelch-like family member 28
KLHL29 kelch-like family member 29
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LEFTY1 left-right determination factor 1
LIME1 Lck interacting transmembrane adaptor 1
MEIS1 Meis homeobox 1
MNX1 motor neuron and pancreas homeobox 1
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MUM1 melanoma associated antigen (mutated) 1
NPFFR1 neuropeptide FF receptor 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PARP6 poly (ADP-ribose) polymerase family, member 6
PER3 period circadian clock 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF14 PHD finger protein 14
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PQLC2 PQ loop repeat containing 2
PRB3 proline-rich protein BstNI subfamily 3
PTPRH protein tyrosine phosphatase, receptor type, H
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC35F6 solute carrier family 35, member F6
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNRPN small nuclear ribonucleoprotein polypeptide N
SOSTDC1 sclerostin domain containing 1
STARD13 StAR-related lipid transfer (START) domain containing 13
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMEM180 transmembrane protein 180
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VASH2 vasohibin 2
VAV1 vav 1 guanine nucleotide exchange factor
VN1R1 vomeronasal 1 receptor 1
WDR33 WD repeat domain 33
WNT16 wingless-type MMTV integration site family, member 16
ZNF32 zinc finger protein 32
ZNF34 zinc finger protein 34
ZNF639 zinc finger protein 639
ZNF671 zinc finger protein 671
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein