estradiol-414 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the estradiol-414 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APOA1 apolipoprotein A-I
APOC1 apolipoprotein C-I
ARRB1 arrestin, beta 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCORL1 BCL6 corepressor-like 1
BTN2A1 butyrophilin, subfamily 2, member A1
C16ORF58 chromosome 16 open reading frame 58
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASKIN2 CASK interacting protein 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCPG1 cell cycle progression 1
CCSER2 coiled-coil serine-rich protein 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH22 cadherin 22, type 2
CEP41 centrosomal protein 41kDa
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNGB3 cyclic nucleotide gated channel beta 3
CRAT carnitine O-acetyltransferase
CREB1 cAMP responsive element binding protein 1
CST8 cystatin 8 (cystatin-related epididymal specific)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAXX death-domain associated protein
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DRD2 dopamine receptor D2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ESR2 estrogen receptor 2 (ER beta)
FAM188A family with sequence similarity 188, member A
FGL1 fibrinogen-like 1
FOXO1 forkhead box O1
GALK2 galactokinase 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HIST1H2AI histone cluster 1, H2ai
HIST1H2BN histone cluster 1, H2bn
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HUS1 HUS1 checkpoint homolog (S. pombe)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFFO1 intermediate filament family orphan 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IL6R interleukin 6 receptor
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM4B lysine (K)-specific demethylase 4B
KRT9 keratin 9, type I
LUC7L LUC7-like (S. cerevisiae)
MASP2 mannan-binding lectin serine peptidase 2
MED18 mediator complex subunit 18
MGA MGA, MAX dimerization protein
MOGAT2 monoacylglycerol O-acyltransferase 2
MPZ myelin protein zero
MTRF1 mitochondrial translational release factor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO7A myosin VIIA
MYO9B myosin IXB
NADK NAD kinase
NUPL2 nucleoporin like 2
OPRL1 opiate receptor-like 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMEL premelanosome protein
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RBL2 retinoblastoma-like 2
RET ret proto-oncogene
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B1 SH2B adaptor protein 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
STRN striatin, calmodulin binding protein
STYK1 serine/threonine/tyrosine kinase 1
SUGP2 SURP and G patch domain containing 2
SYNGR1 synaptogyrin 1
TBC1D29 TBC1 domain family, member 29
TF transferrin
TMEM161A transmembrane protein 161A
TMEM206 transmembrane protein 206
TMF1 TATA element modulatory factor 1
TRIM10 tripartite motif containing 10
TRIP11 thyroid hormone receptor interactor 11
TSHB thyroid stimulating hormone, beta
UBOX5 U-box domain containing 5
USP46 ubiquitin specific peptidase 46
VARS valyl-tRNA synthetase
WDR13 WD repeat domain 13
YIPF6 Yip1 domain family, member 6
ZNF184 zinc finger protein 184
ZNF354A zinc finger protein 354A
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ALAD aminolevulinate dehydratase
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP8 aquaporin 8
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC7 armadillo repeat containing 7
ARRB2 arrestin, beta 2
ASB7 ankyrin repeat and SOCS box containing 7
BAGE B melanoma antigen
BCL7C B-cell CLL/lymphoma 7C
BTBD2 BTB (POZ) domain containing 2
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CBX8 chromobox homolog 8
CD38 CD38 molecule
CD5 CD5 molecule
CDK5 cyclin-dependent kinase 5
CENPE centromere protein E, 312kDa
CEP192 centrosomal protein 192kDa
CLIP3 CAP-GLY domain containing linker protein 3
COPZ2 coatomer protein complex, subunit zeta 2
CORO2A coronin, actin binding protein, 2A
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CROT carnitine O-octanoyltransferase
CTRB2 chymotrypsinogen B2
DAGLA diacylglycerol lipase, alpha
DYSF dysferlin
ELMO3 engulfment and cell motility 3
ELP6 elongator acetyltransferase complex subunit 6
EXD3 exonuclease 3'-5' domain containing 3
FAM110D family with sequence similarity 110, member D
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FCHO1 FCH domain only 1
FGF4 fibroblast growth factor 4
FOLR2 folate receptor 2 (fetal)
FRAS1 Fraser extracellular matrix complex subunit 1
FSCN3 fascin actin-bundling protein 3, testicular
FSD1 fibronectin type III and SPRY domain containing 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAST gastrin
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GREB1L growth regulation by estrogen in breast cancer-like
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KLHL28 kelch-like family member 28
KPTN kaptin (actin binding protein)
LIMS2 LIM and senescent cell antigen-like domains 2
LY86 lymphocyte antigen 86
MCM9 minichromosome maintenance complex component 9
MED9 mediator complex subunit 9
MUC2 mucin 2, oligomeric mucus/gel-forming
NELL2 NEL-like 2 (chicken)
NMU neuromedin U
NRGN neurogranin (protein kinase C substrate, RC3)
PLAC1 placenta-specific 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PMP22 peripheral myelin protein 22
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POMT2 protein-O-mannosyltransferase 2
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PTK6 protein tyrosine kinase 6
RAB8B RAB8B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIPK4 receptor-interacting serine-threonine kinase 4
RNF208 ring finger protein 208
RNF220 ring finger protein 220
RNF39 ring finger protein 39
SAG S-antigen; retina and pineal gland (arrestin)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
SURF2 surfeit 2
SYNGR3 synaptogyrin 3
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TLR5 toll-like receptor 5
TMEM176A transmembrane protein 176A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPYL2 TSPY-like 2
TTR transthyretin
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN4 ubiquilin 4
UBXN2B UBX domain protein 2B
VEGFB vascular endothelial growth factor B
VWA1 von Willebrand factor A domain containing 1
XPA xeroderma pigmentosum, complementation group A
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZNF140 zinc finger protein 140
ZNF286A zinc finger protein 286A
ZNF710 zinc finger protein 710
ZXDC ZXD family zinc finger C