essential hypertension Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hypertension with no known cause. It is the most common type of hypertension. (Human Disease Ontology, DOID_10825)
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Genes

81 genes associated with the disease essential hypertension in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RPL6 ribosomal protein L6 1.90585
CSK c-src tyrosine kinase 1.52269
FGF5 fibroblast growth factor 5 1.43901
ARHGAP42 Rho GTPase activating protein 42 1.24299
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.24299
NT5C2 5'-nucleotidase, cytosolic II 1.09588
HFE hemochromatosis 1.07383
SH2B3 SH2B adaptor protein 3 0.995303
LOC340340 uncharacterized LOC340340 0.945428
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.945428
HIST1H1T histone cluster 1, H1t 0.872896
ADM adrenomedullin 0.85991
EBF1 early B-cell factor 1 0.817078
BAG6 BCL2-associated athanogene 6 0.790827
FIGN fidgetin 0.7623
UMOD uromodulin 0.7623
GOSR2 golgi SNAP receptor complex member 2 0.724323
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.724323
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.724323
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.69843
CPLX3 complexin 3 0.69843
C10ORF107 chromosome 10 open reading frame 107 0.63207
MOV10 Mov10 RISC complex RNA helicase 0.63207
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.602429
ADRB1 adrenoceptor beta 1 0.602429
ULK4 unc-51 like kinase 4 0.58494
NOV nephroblastoma overexpressed 0.572184
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.572184
PLCE1 phospholipase C, epsilon 1 0.561725
POC1B POC1 centriolar protein B 0.544585
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.5306
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.52461
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.52461
RPL21P44 ribosomal protein L21 pseudogene 44 0.52461
PLCD3 phospholipase C, delta 3 0.52461
ATXN2 ataxin 2 0.486425
NPR3 natriuretic peptide receptor 3 0.486425
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.464771
MAP4 microtubule-associated protein 4 0.464771
LRRC7 leucine rich repeat containing 7 0.464771
FES FES proto-oncogene, tyrosine kinase 0.464771
FSTL4 follistatin-like 4 0.408752
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.403461
PHACTR1 phosphatase and actin regulator 1 0.403461
TRAFD1 TRAF-type zinc finger domain containing 1 0.403461
MECOM MDS1 and EVI1 complex locus 0.403461
STK39 serine threonine kinase 39 0.368757
ZNF652 zinc finger protein 652 0.368757
PARP14 poly (ADP-ribose) polymerase family, member 14 0.368757
BRAP BRCA1 associated protein 0.368757
CASZ1 castor zinc finger 1 0.368757
ZNF831 zinc finger protein 831 0.368757
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.345945
TMEM212 transmembrane protein 212 0.327313
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.311576
ITGA9 integrin, alpha 9 0.311576
C2ORF88 chromosome 2 open reading frame 88 0.285417
MYO16 myosin XVI 0.285417
RGS1 regulator of G-protein signaling 1 0.264872
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.264872
RGMA repulsive guidance molecule family member a 0.256228
PRRX1 paired related homeobox 1 0.256228
GPR83 G protein-coupled receptor 83 0.197766
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.197766
JAKMIP1 janus kinase and microtubule interacting protein 1 0.197766
SYNRG synergin, gamma 0.197766
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.15771
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.15771
MSRA methionine sulfoxide reductase A 0.126165
KDM4A lysine (K)-specific demethylase 4A 0.126165
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.100789
MYO1D myosin ID 0.100789
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.100789
IQSEC3 IQ motif and Sec7 domain 3 0.080593
TMC7 transmembrane channel-like 7 0.080593
C3ORF56 chromosome 3 open reading frame 56 0.080593
EYA4 EYA transcriptional coactivator and phosphatase 4 0.080593
BMPR1B bone morphogenetic protein receptor, type IB 0.064973
IDI2 isopentenyl-diphosphate delta isomerase 2 0.052255
IGFBPL1 insulin-like growth factor binding protein-like 1 0.052255
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 0.043246