esophageal squamous cell carcinoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Squamous cell carcinoma is the most common type of esophageal cancer, accounting for 95% of all esophageal cancers worldwide. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002861)
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Genes

316 proteins co-occuring with the tissue esophageal squamous cell carcinoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
HACD4 3-hydroxyacyl-CoA dehydratase 4 1.96251
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.81073
DEC1 deleted in esophageal cancer 1 1.79195
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 1.54295
GPR158 G protein-coupled receptor 158 1.45983
C2ORF40 chromosome 2 open reading frame 40 1.38139
RBMS3 RNA binding motif, single stranded interacting protein 3 1.37819
FAM135B family with sequence similarity 135, member B 1.33139
C15ORF48 chromosome 15 open reading frame 48 1.31874
CCND1 cyclin D1 1.30748
TMPRSS11A transmembrane protease, serine 11A 1.30073
STOML2 stomatin (EPB72)-like 2 1.28188
MIR25 microRNA 25 1.28053
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 1.2586
ZIK1 zinc finger protein interacting with K protein 1 1.24878
ZSCAN18 zinc finger and SCAN domain containing 18 1.19223
DIRAS1 DIRAS family, GTP-binding RAS-like 1 1.16914
BAGE3 B melanoma antigen family, member 3 1.13723
S100A14 S100 calcium binding protein A14 1.08015
FSCN1 fascin actin-bundling protein 1 1.07706
SYF2 SYF2 pre-mRNA-splicing factor 1.07221
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.07132
RSRC2 arginine/serine-rich coiled-coil 2 1.06956
DENND2D DENN/MADD domain containing 2D 1.00719
THSD1 thrombospondin, type I, domain containing 1 0.996731
RSPO4 R-spondin 4 0.985425
WRAP53 WD repeat containing, antisense to TP53 0.979783
CTNND2 catenin (cadherin-associated protein), delta 2 0.978482
MINA MYC induced nuclear antigen 0.933624
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 0.925479
MIR203A microRNA 203a 0.925051
CKS2 CDC28 protein kinase regulatory subunit 2 0.915215
CDC25B cell division cycle 25B 0.91308
LOXL2 lysyl oxidase-like 2 0.881627
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.879512
CCDC88A coiled-coil domain containing 88A 0.878243
TSPYL5 TSPY-like 5 0.875706
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.869373
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.866842
SETD1B SET domain containing 1B 0.864734
MIR145 microRNA 145 0.8601
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.855891
MIR21 microRNA 21 0.852106
FAM84B family with sequence similarity 84, member B 0.852106
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.849585
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.829453
TSPYL4 TSPY-like 4 0.826523
CDK6 cyclin-dependent kinase 6 0.810638
FSCN3 fascin actin-bundling protein 3, testicular 0.810221
CSNK1A1 casein kinase 1, alpha 1 0.803127
REPS2 RALBP1 associated Eps domain containing 2 0.801876
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.800208
SMYD2 SET and MYND domain containing 2 0.799791
TP53 tumor protein p53 0.799375
FSCN2 fascin actin-bundling protein 2, retinal 0.796874
CIAO1 cytosolic iron-sulfur assembly component 1 0.795208
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.793126
PDGFRL platelet-derived growth factor receptor-like 0.791044
RARB retinoic acid receptor, beta 0.78938
RAB37 RAB37, member RAS oncogene family 0.788964
RPL6 ribosomal protein L6 0.783141
WIF1 WNT inhibitory factor 1 0.78231
NKX2-8 NK2 homeobox 8 0.769027
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.768612
ORAOV1 oral cancer overexpressed 1 0.768197
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.763226
MIR100 microRNA 100 0.761155
PLCD1 phospholipase C, delta 1 0.754124
CDK4 cyclin-dependent kinase 4 0.751645
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.745864
ADAM29 ADAM metallopeptidase domain 29 0.745451
AKIP1 A kinase (PRKA) interacting protein 1 0.73803
DSC2 desmocollin 2 0.735559
CENPF centromere protein F, 350/400kDa 0.726507
MMP26 matrix metallopeptidase 26 0.721166
COX6C cytochrome c oxidase subunit VIc 0.720345
RPN2 ribophorin II 0.71583
PTEN phosphatase and tensin homolog 0.713779
CDH13 cadherin 13 0.707221
PHF8 PHD finger protein 8 0.705583
SHROOM2 shroom family member 2 0.702717
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.701899
UBE2M ubiquitin-conjugating enzyme E2M 0.699035
MED23 mediator complex subunit 23 0.699035
SSBP2 single-stranded DNA binding protein 2 0.699035
E2F5 E2F transcription factor 5, p130-binding 0.691268
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.675357
SERBP1 SERPINE1 mRNA binding protein 1 0.674543
EIF5A2 eukaryotic translation initiation factor 5A2 0.667622
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.667215
ERP44 endoplasmic reticulum protein 44 0.665588
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.658678
MCRS1 microspherule protein 1 0.658272
MMP21 matrix metallopeptidase 21 0.654212
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.644074
EHD2 EH-domain containing 2 0.642858
MYEOV myeloma overexpressed 0.639214
NDRG2 NDRG family member 2 0.63274
ERO1L ERO1-like (S. cerevisiae) 0.626273
MMP2 matrix metallopeptidase 2 0.624658
S100A4 S100 calcium binding protein A4 0.623043
MIR98 microRNA 98 0.609332
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.609332
PCDH17 protocadherin 17 0.604904
RAD51 RAD51 recombinase 0.599675
CYR61 cysteine-rich, angiogenic inducer, 61 0.599273
TSGA10 testis specific, 10 0.598067
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.589234
ITGB4 integrin, beta 4 0.585625
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.585625
STOM stomatin 0.584823
FGF4 fibroblast growth factor 4 0.579617
EMP3 epithelial membrane protein 3 0.578816
MAD2L1P1 MAD2 mitotic arrest deficient-like 1 (yeast) pseudogene 1 0.575216
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.574816
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.573217
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.566828
PPP1R3A protein phosphatase 1, regulatory subunit 3A 0.566428
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.564434
HAUS3 HAUS augmin-like complex, subunit 3 0.564434
SOX6 SRY (sex determining region Y)-box 6 0.562441
CCAR2 cell cycle and apoptosis regulator 2 0.561245
MT1M metallothionein 1M 0.555274
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.554876
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.552888
FLOT1 flotillin 1 0.549312
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.549312
HAS3 hyaluronan synthase 3 0.548517
SPRR3 small proline-rich protein 3 0.546533
LRP1B low density lipoprotein receptor-related protein 1B 0.544152
DUSP6 dual specificity phosphatase 6 0.543756
PLK1 polo-like kinase 1 0.542963
HSPB2 heat shock 27kDa protein 2 0.541773
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 0.536229
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.534251
BIRC6 baculoviral IAP repeat containing 6 0.533856
PARD3 par-3 family cell polarity regulator 0.533065
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.53267
TTN titin 0.531484
FAM134B family with sequence similarity 134, member B 0.530298
RABAC1 Rab acceptor 1 (prenylated) 0.529508
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.523194
KRT4 keratin 4, type II 0.520041
KRT13 keratin 13, type I 0.520041
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.517284
GPX7 glutathione peroxidase 7 0.516104
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.512957
KLF5 Kruppel-like factor 5 (intestinal) 0.50942
EGFR epidermal growth factor receptor 0.50942
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.507064
EZR ezrin 0.505887
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.504318
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.50275
PLCE1 phospholipase C, epsilon 1 0.492182
MACC1 metastasis associated in colon cancer 1 0.490229
WNT2 wingless-type MMTV integration site family member 2 0.489447
ATF3 activating transcription factor 3 0.489057
ZFP42 ZFP42 zinc finger protein 0.486716
MADD MAP-kinase activating death domain 0.485545
MMP9 matrix metallopeptidase 9 0.483986
PBX2 pre-B-cell leukemia homeobox 2 0.482038
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.48048
BIRC5 baculoviral IAP repeat containing 5 0.478145
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.478145
FERMT2 fermitin family member 2 0.478145
SFRP2 secreted frizzled-related protein 2 0.471927
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.469211
TNK2 tyrosine kinase, non-receptor, 2 0.46766
DIABLO diablo, IAP-binding mitochondrial protein 0.46766
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.461078
SUB1 SUB1 homolog (S. cerevisiae) 0.458759
CCNB1 cyclin B1 0.458759
PFKL phosphofructokinase, liver 0.4576
PRKCI protein kinase C, iota 0.454126
CTHRC1 collagen triple helix repeat containing 1 0.449116
MTDH metadherin 0.448731
GGCT gamma-glutamylcyclotransferase 0.447192
PTTG1 pituitary tumor-transforming 1 0.446807
UPK1A uroplakin 1A 0.446807
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.445653
RAB25 RAB25, member RAS oncogene family 0.43989
POU3F3 POU class 3 homeobox 3 0.438356
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.435289
FGF19 fibroblast growth factor 19 0.432225
SPRY4 sprouty homolog 4 (Drosophila) 0.427636
TPM4 tropomyosin 4 0.424199
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.417337
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.416957
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.416957
ZEB2 zinc finger E-box binding homeobox 2 0.416576
GDI2 GDP dissociation inhibitor 2 0.415434
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.412771
ZMYND10 zinc finger, MYND-type containing 10 0.412011
CTSV cathepsin V 0.411251
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.409731
ANXA1 annexin A1 0.407453
MIR15B microRNA 15b 0.406315
KAT2B K(lysine) acetyltransferase 2B 0.405935
CDK2 cyclin-dependent kinase 2 0.404797
ECT2 epithelial cell transforming 2 0.404039
ERBB2 erb-b2 receptor tyrosine kinase 2 0.402523
MIR133B microRNA 133b 0.402144
MIR10A microRNA 10a 0.401765
DVL3 dishevelled segment polarity protein 3 0.401765
MT1G metallothionein 1G 0.400628
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.398735
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.398735
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.398357
MIR183 microRNA 183 0.395709
PARP1 poly (ADP-ribose) polymerase 1 0.388158
PKP1 plakophilin 1 0.381379
MIR214 microRNA 214 0.380627
GPR39 G protein-coupled receptor 39 0.379875
MIR27B microRNA 27b 0.377245
NOXO1 NADPH oxidase organizer 1 0.375743
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.374993
NFIL3 nuclear factor, interleukin 3 regulated 0.374243
IVL involucrin 0.373868
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.371619
LTBP3 latent transforming growth factor beta binding protein 3 0.370496
CLDN6 claudin 6 0.368624
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.364886
TPX2 TPX2, microtubule-associated 0.359664
LTBP2 latent transforming growth factor beta binding protein 2 0.358174
TWIST1 twist family bHLH transcription factor 1 0.357058
CALR calreticulin 0.353712
PYCARD PYD and CARD domain containing 0.352227
H2AFX H2A histone family, member X 0.350743
CCNG2 cyclin G2 0.346668
RUNX3 runt-related transcription factor 3 0.344449
BHLHE40 basic helix-loop-helix family, member e40 0.34334
MIR192 microRNA 192 0.341863
PTK6 protein tyrosine kinase 6 0.340757
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.33965
FOSL1 FOS-like antigen 1 0.334865
NUPR1 nuclear protein, transcriptional regulator, 1 0.333396
CTTN cortactin 0.331927
ITGA6 integrin, alpha 6 0.331194
NEFH neurofilament, heavy polypeptide 0.32497
MAP4 microtubule-associated protein 4 0.324605
CTBP2 C-terminal binding protein 2 0.323509
BIRC2 baculoviral IAP repeat containing 2 0.322414
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.317679
FHIT fragile histidine triad 0.316588
SULF1 sulfatase 1 0.316224
CRNN cornulin 0.315861
PDPN podoplanin 0.307889
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.307167
ATF4 activating transcription factor 4 0.305361
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.300679
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.300679
VEGFC vascular endothelial growth factor C 0.30032
IGFBP3 insulin-like growth factor binding protein 3 0.296372
CDK11A cyclin-dependent kinase 11A 0.295297
ALOX15 arachidonate 15-lipoxygenase 0.293508
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.293508
FLOT2 flotillin 2 0.290652
METAP2 methionyl aminopeptidase 2 0.284607
MMP7 matrix metallopeptidase 7 0.284607
MAPK7 mitogen-activated protein kinase 7 0.284253
CRABP1 cellular retinoic acid binding protein 1 0.283191
HRAS Harvey rat sarcoma viral oncogene homolog 0.277549
WNT5A wingless-type MMTV integration site family, member 5A 0.276846
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.276145
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.276145
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.274744
CCNE2 cyclin E2 0.273696
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.266757
EIF5A eukaryotic translation initiation factor 5A 0.266757
ULK1 unc-51 like autophagy activating kinase 1 0.265725
TYMS thymidylate synthetase 0.265038
CHEK1 checkpoint kinase 1 0.259591
CSTA cystatin A (stefin A) 0.259254
BIRC3 baculoviral IAP repeat containing 3 0.258917
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.25858
RAP1B RAP1B, member of RAS oncogene family 0.257907
PTPRD protein tyrosine phosphatase, receptor type, D 0.257237
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.255567
UMPS uridine monophosphate synthetase 0.255234
HYAL2 hyaluronoglucosaminidase 2 0.253248
FOXC1 forkhead box C1 0.252261
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.249329
HOPX HOP homeobox 0.248683
VEGFA vascular endothelial growth factor A 0.246124
MTSS1 metastasis suppressor 1 0.245175
YAP1 Yes-associated protein 1 0.244232
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.242983
NEO1 neogenin 1 0.23781
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.236921
RB1 retinoblastoma 1 0.236921
MSN moesin 0.236627
CTGF connective tissue growth factor 0.23459
MTAP methylthioadenosine phosphorylase 0.233731
GSTM3 glutathione S-transferase mu 3 (brain) 0.232881
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.23011
ANXA5 annexin A5 0.229839
CDKN2A cyclin-dependent kinase inhibitor 2A 0.228234
EPHA3 EPH receptor A3 0.227707
ZHX2 zinc fingers and homeoboxes 2 0.227186
NGFR nerve growth factor receptor 0.225647
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.224645
PCNA proliferating cell nuclear antigen 0.224398
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.222699
DROSHA drosha, ribonuclease type III 0.221291
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.220604
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.219485
DGCR8 DGCR8 microprocessor complex subunit 0.219264
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.219047
CCND2 cyclin D2 0.21883
MIR223 microRNA 223 0.218613
SNAI2 snail family zinc finger 2 0.217554
MTA1 metastasis associated 1 0.217346
PCDH11Y protocadherin 11 Y-linked 0.216528
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.216325
PGAM2 phosphoglycerate mutase 2 (muscle) 0.214576
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.212761