esophageal cancer Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A gastrointestinal system cancer that is located_in the esophagus. (Human Disease Ontology, DOID_5041)
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Genes

112 genes associated with the disease esophageal cancer in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH6 alcohol dehydrogenase 6 (class V)
ADIPOQ adiponectin, C1Q and collagen domain containing
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AR androgen receptor
AURKA aurora kinase A
BRAP BRCA1 associated protein
BRCA2 breast cancer 2, early onset
CCND1 cyclin D1
CCNH cyclin H
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNR1 cannabinoid receptor 1 (brain)
CRP C-reactive protein, pentraxin-related
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DROSHA drosha, ribonuclease type III
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
GEMIN4 gem (nuclear organelle) associated protein 4
GHRL ghrelin/obestatin prepropeptide
GNAS GNAS complex locus
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IFNG interferon, gamma
IL10 interleukin 10
IL12B interleukin 12B
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
INSIG2 insulin induced gene 2
IRF3 interferon regulatory factor 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
LIG3 ligase III, DNA, ATP-dependent
MBD4 methyl-CpG binding domain protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MIR100 microRNA 100
MIR124-1 microRNA 124-1
MIR146A microRNA 146a
MIR196A2 microRNA 196a-2
MIR219A1 microRNA 219a-1
MIR26A1 microRNA 26a-1
MIR30A microRNA 30a
MIR30C1 microRNA 30c-1
MIR373 microRNA 373
MIR423 microRNA 423
MIR492 microRNA 492
MIR604 microRNA 604
MIR608 microRNA 608
MIR631 microRNA 631
MMP2 matrix metallopeptidase 2
MPO myeloperoxidase
MT-ND2 MTND2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NQO1 NAD(P)H dehydrogenase, quinone 1
OGG1 8-oxoguanine DNA glycosylase
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIWIL1 piwi-like RNA-mediated gene silencing 1
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD23B RAD23 homolog B (S. cerevisiae)
RAN RAN, member RAS oncogene family
RB1 retinoblastoma 1
RXRG retinoid X receptor, gamma
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TARBP2 TAR (HIV-1) RNA binding protein 2
TGFB1 transforming growth factor, beta 1
TMPRSS11A transmembrane protease, serine 11A
TNF tumor necrosis factor
TP53 tumor protein p53
TP73 tumor protein p73
TYMS thymidylate synthetase
VEGFA vascular endothelial growth factor A
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XPO5 exportin 5
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3