esophageal cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A gastrointestinal system cancer that is located_in the esophagus. (Human Disease Ontology, DOID_5041)
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Genes

720 genes co-occuring with the disease esophageal cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TP53 tumor protein p53 1.94924
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.83773
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 1.60457
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.57957
CCND1 cyclin D1 1.55026
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.51809
C2ORF40 chromosome 2 open reading frame 40 1.50579
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.39608
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.3869
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.38647
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.35245
PLCE1 phospholipase C, epsilon 1 1.33283
EGFR epidermal growth factor receptor 1.3241
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.27737
ERBB2 erb-b2 receptor tyrosine kinase 2 1.23429
CDKN2A cyclin-dependent kinase inhibitor 2A 1.19186
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.18755
PDPN podoplanin 1.18582
FHIT fragile histidine triad 1.17937
FGF4 fibroblast growth factor 4 1.1635
ZNF135 zinc finger protein 135 1.14305
GSTP1 glutathione S-transferase pi 1 1.13501
GSTM1 glutathione S-transferase mu 1 1.11393
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 1.11393
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.08957
PCNA proliferating cell nuclear antigen 1.07446
KLK7 kallikrein-related peptidase 7 1.05765
MIR21 microRNA 21 1.05303
ALB albumin 1.05261
VEGFC vascular endothelial growth factor C 1.04882
BAX BCL2-associated X protein 1.01849
NPY1R neuropeptide Y receptor Y1 1.01765
GSTTP1 glutathione S-transferase theta pseudogene 1 1.01427
GSTT1 glutathione S-transferase theta 1 1.01385
ERCC1 excision repair cross-complementation group 1 0.988535
BIRC5 baculoviral IAP repeat containing 5 0.9839
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 0.949936
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.947435
SCN10A sodium channel, voltage gated, type X alpha subunit 0.922974
HRAS Harvey rat sarcoma viral oncogene homolog 0.909787
EMILIN3 elastin microfibril interfacer 3 0.88475
MMP2 matrix metallopeptidase 2 0.875329
CD6 CD6 molecule 0.86714
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.864684
TMPRSS11B transmembrane protease, serine 11B 0.863046
DEC1 deleted in esophageal cancer 1 0.86059
ERCC2 excision repair cross-complementation group 2 0.854449
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.852402
SPRR3 small proline-rich protein 3 0.851173
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.846669
KRT4 keratin 4, type II 0.84585
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.842573
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.827819
SLC44A3 solute carrier family 44, member 3 0.827819
CDX2 caudal type homeobox 2 0.823718
MTL5 metallothionein-like 5, testis-specific (tesmin) 0.822488
CXCR4 chemokine (C-X-C motif) receptor 4 0.817155
MIR145 microRNA 145 0.802385
MIR203A microRNA 203a 0.795411
GRB7 growth factor receptor-bound protein 7 0.791721
ANXA1 annexin A1 0.778204
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.77575
UBE2O ubiquitin-conjugating enzyme E2O 0.771252
IL6 interleukin 6 0.765127
FZD7 frizzled class receptor 7 0.760639
TYMS thymidylate synthetase 0.760639
HPD 4-hydroxyphenylpyruvate dioxygenase 0.756156
CRP C-reactive protein, pentraxin-related 0.753306
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.750864
METTL21A methyltransferase like 21A 0.747204
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.742735
HPSE heparanase 0.741111
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.740299
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 0.738676
DPYD dihydropyrimidine dehydrogenase 0.732191
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.728952
VEGFA vascular endothelial growth factor A 0.728952
STK31 serine/threonine kinase 31 0.728143
CDK4 cyclin-dependent kinase 4 0.727738
DZIP1L DAZ interacting zinc finger protein 1-like 0.72612
GSTA1 glutathione S-transferase alpha 1 0.725716
TEF thyrotrophic embryonic factor 0.725311
GAST gastrin 0.724502
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.724098
GSTA4 glutathione S-transferase alpha 4 0.716828
TTR transthyretin 0.715215
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 0.712796
GSTA3 glutathione S-transferase alpha 3 0.711989
GSTA2 glutathione S-transferase alpha 2 0.710378
NAIF1 nuclear apoptosis inducing factor 1 0.710378
TYMP thymidine phosphorylase 0.702732
TMPRSS11A transmembrane protease, serine 11A 0.701124
TERT telomerase reverse transcriptase 0.699919
GPS1 G protein pathway suppressor 1 0.698313
ANKRD11 ankyrin repeat domain 11 0.695103
MAN2C1 mannosidase, alpha, class 2C, member 1 0.6939
CCNB1 cyclin B1 0.685891
GPS2 G protein pathway suppressor 2 0.684692
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.679499
TNRC6C trinucleotide repeat containing 6C 0.6791
NXN nucleoredoxin 0.678302
WFDC5 WAP four-disulfide core domain 5 0.671527
SAMM50 SAMM50 sorting and assembly machinery component 0.67113
MTA1 metastasis associated 1 0.668345
FSCN1 fascin actin-bundling protein 1 0.664769
MMP8 matrix metallopeptidase 8 0.6608
PLK1 polo-like kinase 1 0.660404
MUC1 mucin 1, cell surface associated 0.660008
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 0.658818
KRT16 keratin 16, type I 0.654067
ZNF207 zinc finger protein 207 0.650903
CTAG2 cancer/testis antigen 2 0.648533
THSD1 thrombospondin, type I, domain containing 1 0.644981
HPGDS hematopoietic prostaglandin D synthase 0.644981
RPL15 ribosomal protein L15 0.643404
CD44 CD44 molecule (Indian blood group) 0.637495
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.634742
MMP9 matrix metallopeptidase 9 0.631991
MMP7 matrix metallopeptidase 7 0.629242
TGM3 transglutaminase 3 0.615529
DCTPP1 dCTP pyrophosphatase 1 0.612011
PPL periplakin 0.610057
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.608885
GPX7 glutathione peroxidase 7 0.606933
DNAH17 dynein, axonemal, heavy chain 17 0.606152
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.60342
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 0.60147
CD34 CD34 molecule 0.60147
HID1 HID1 domain containing 0.597961
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.588222
ZRANB3 zinc finger, RAN-binding domain containing 3 0.584719
HOXC6 homeobox C6 0.578494
SRY sex determining region Y 0.572273
SLC46A2 solute carrier family 46, member 2 0.565666
MIR192 microRNA 192 0.564112
KRT13 keratin 13, type I 0.561004
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.557897
RSRC2 arginine/serine-rich coiled-coil 2 0.556344
GHRL ghrelin/obestatin prepropeptide 0.555568
IGF1R insulin-like growth factor 1 receptor 0.55518
KIAA1804 mixed lineage kinase 4 0.552851
SGPP2 sphingosine-1-phosphate phosphatase 2 0.550134
RPP21 ribonuclease P/MRP 21kDa subunit 0.550134
ZNRD1 zinc ribbon domain containing 1 0.549359
TGFB1 transforming growth factor, beta 1 0.549359
GPX2 glutathione peroxidase 2 0.547032
ORAOV1 oral cancer overexpressed 1 0.544318
RARB retinoic acid receptor, beta 0.542767
RBBP6 retinoblastoma binding protein 6 0.540055
SOX17 SRY (sex determining region Y)-box 17 0.53928
KRAS Kirsten rat sarcoma viral oncogene homolog 0.531541
BCL2 B-cell CLL/lymphoma 2 0.530768
ODC1 ornithine decarboxylase 1 0.529222
HELQ helicase, POLQ-like 0.528063
ELANE elastase, neutrophil expressed 0.528063
TMEM11 transmembrane protein 11 0.527676
RUNX3 runt-related transcription factor 3 0.526904
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.526518
HLA-C major histocompatibility complex, class I, C 0.526518
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.524588
FASLG Fas ligand (TNF superfamily, member 6) 0.524202
TF transferrin 0.521502
KLF5 Kruppel-like factor 5 (intestinal) 0.518805
MINA MYC induced nuclear antigen 0.516494
CCNG2 cyclin G2 0.512264
MAL mal, T-cell differentiation protein 0.51188
ANXA13 annexin A13 0.511112
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.509959
RPL28 ribosomal protein L28 0.508424
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.50689
ACP6 acid phosphatase 6, lysophosphatidic 0.506123
LY6K lymphocyte antigen 6 complex, locus K 0.506123
GOSR1 golgi SNAP receptor complex member 1 0.504207
FAM84B family with sequence similarity 84, member B 0.502292
ZXDC ZXD family zinc finger C 0.501527
ANXA5 annexin A5 0.500379
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.498085
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.496939
FLT1 fms-related tyrosine kinase 1 0.496175
MUC2 mucin 2, oligomeric mucus/gel-forming 0.493885
ANO4 anoctamin 4 0.488169
HEBP2 heme binding protein 2 0.485125
FOXF1 forkhead box F1 0.482464
GADD45B growth arrest and DNA-damage-inducible, beta 0.480945
CXCL8 chemokine (C-X-C motif) ligand 8 0.479047
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.478668
PRDX1 peroxiredoxin 1 0.477909
FAT4 FAT atypical cadherin 4 0.474498
NQO2 NAD(P)H dehydrogenase, quinone 2 0.47374
BCL2L1 BCL2-like 1 0.472604
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.467684
FOXC2 forkhead box C2 0.464283
JUN jun proto-oncogene 0.462016
MDC1 mediator of DNA-damage checkpoint 1 0.457864
GADD45A growth arrest and DNA-damage-inducible, alpha 0.454847
ERCC4 excision repair cross-complementation group 4 0.453339
PDPK1 3-phosphoinositide dependent protein kinase 1 0.451831
NFAM1 NFAT activating protein with ITAM motif 1 0.449947
MAGEA3 melanoma antigen family A3 0.449947
DZIP1 DAZ interacting zinc finger protein 1 0.448441
KRT14 keratin 14, type I 0.447311
FARSB phenylalanyl-tRNA synthetase, beta subunit 0.444676
MMP1 matrix metallopeptidase 1 0.443547
SOX2 SRY (sex determining region Y)-box 2 0.441666
DEGS2 delta(4)-desaturase, sphingolipid 2 0.439034
IFITM1 interferon induced transmembrane protein 1 0.437906
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.437154
BTG1 B-cell translocation gene 1, anti-proliferative 0.437154
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.436778
STK36 serine/threonine kinase 36 0.436778
GCAT glycine C-acetyltransferase 0.436402
MUC6 mucin 6, oligomeric mucus/gel-forming 0.434524
FOXL1 forkhead box L1 0.434524
HNF4A hepatocyte nuclear factor 4, alpha 0.434148
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.428891
SOD2 superoxide dismutase 2, mitochondrial 0.426265
AURKA aurora kinase A 0.42364
MKI67 marker of proliferation Ki-67 0.42364
MAGEA1 melanoma antigen family A1 0.423265
EYA4 EYA transcriptional coactivator and phosphatase 4 0.421016
CD4 CD4 molecule 0.420641
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.419517
MCM4 minichromosome maintenance complex component 4 0.417644
EMP1 epithelial membrane protein 1 0.41727
MIRLET7C microRNA let-7c 0.415024
HOXC8 homeobox C8 0.415024
MGMT O-6-methylguanine-DNA methyltransferase 0.413901
MET MET proto-oncogene, receptor tyrosine kinase 0.413527
DENND2D DENN/MADD domain containing 2D 0.412031
MRPS12 mitochondrial ribosomal protein S12 0.410535
SUFU suppressor of fused homolog (Drosophila) 0.410161
HOOK2 hook microtubule-tethering protein 2 0.409414
RYK receptor-like tyrosine kinase 0.409414
OGG1 8-oxoguanine DNA glycosylase 0.408666
RBMS3 RNA binding motif, single stranded interacting protein 3 0.404931
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.402318
MDK midkine (neurite growth-promoting factor 2) 0.401572
GP5 glycoprotein V (platelet) 0.40008
MTMR9 myotubularin related protein 9 0.398589
SBK1 SH3 domain binding kinase 1 0.397843
PLAU plasminogen activator, urokinase 0.397471
FGFR2 fibroblast growth factor receptor 2 0.396725
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.396353
XPC xeroderma pigmentosum, complementation group C 0.39598
WISP1 WNT1 inducible signaling pathway protein 1 0.393001
CDX1 caudal type homeobox 1 0.392257
MAGOHB mago-nashi homolog B (Drosophila) 0.390397
ZNF296 zinc finger protein 296 0.388909
CBX8 chromobox homolog 8 0.388538
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.387051
ACTB actin, beta 0.385565
NLRP9 NLR family, pyrin domain containing 9 0.385565
CRIP2 cysteine-rich protein 2 0.384822
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.383337
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.379256
SART1 squamous cell carcinoma antigen recognized by T cells 0.378514
MAGEA8 melanoma antigen family A8 0.378143
GLI1 GLI family zinc finger 1 0.374809
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.374809
ACTG1 actin gamma 1 0.374438
PEBP1 phosphatidylethanolamine binding protein 1 0.374438
TTK TTK protein kinase 0.373698
EGR1 early growth response 1 0.372587
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.371107
PTK7 protein tyrosine kinase 7 (inactive) 0.370737
OIP5 Opa interacting protein 5 0.368149
CRYZ crystallin, zeta (quinone reductase) 0.36704
IL27 interleukin 27 0.365193
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.365193
MACC1 metastasis associated in colon cancer 1 0.362978
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.362239
SCEL sciellin 0.36187
NDRG1 N-myc downstream regulated 1 0.360764
CCNL2 cyclin L2 0.358551
IVL involucrin 0.357814
UMPS uridine monophosphate synthetase 0.356709
ALCAM activated leukocyte cell adhesion molecule 0.356341
FBXL19 F-box and leucine-rich repeat protein 19 0.355972
SOX4 SRY (sex determining region Y)-box 4 0.349349
TNF tumor necrosis factor 0.349349
SLC22A17 solute carrier family 22, member 17 0.348614
WIBG within bgcn homolog (Drosophila) 0.345675
LEP leptin 0.344574
DVL3 dishevelled segment polarity protein 3 0.344207
SI sucrase-isomaltase (alpha-glucosidase) 0.34384
ARHGAP9 Rho GTPase activating protein 9 0.343473
FZD2 frizzled class receptor 2 0.342739
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.341639
BANF2 barrier to autointegration factor 2 0.341639
RPL7P32 ribosomal protein L7 pseudogene 32 0.340173
ANXA2 annexin A2 0.33944
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.33944
S100A4 S100 calcium binding protein A4 0.33651
PIR pirin (iron-binding nuclear protein) 0.335778
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.335412
IGF1 insulin-like growth factor 1 (somatomedin C) 0.335046
SRSF7 serine/arginine-rich splicing factor 7 0.334681
NANOG Nanog homeobox 0.334315
RBM38 RNA binding motif protein 38 0.333583
IL20RA interleukin 20 receptor, alpha 0.331391
SHE Src homology 2 domain containing E 0.330295
NDUFA4 NDUFA4, mitochondrial complex associated 0.328105
CRNN cornulin 0.327375
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.32701
IL1B interleukin 1, beta 0.326646
FEN1 flap structure-specific endonuclease 1 0.325916
AJUBA ajuba LIM protein 0.325916
HOXA13 homeobox A13 0.324823
FOXP3 forkhead box P3 0.324823
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.324094
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.322273
CDC25B cell division cycle 25B 0.321909
SSR1 signal sequence receptor, alpha 0.319363
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.318635
GPR17 G protein-coupled receptor 17 0.317182
NKX2-8 NK2 homeobox 8 0.316456
SMO smoothened, frizzled class receptor 0.315003
SOX6 SRY (sex determining region Y)-box 6 0.314278
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.313915
TIMP3 TIMP metallopeptidase inhibitor 3 0.312827
PTEN phosphatase and tensin homolog 0.312827
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.312464
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.312102
IL2 interleukin 2 0.309566
ALYREF Aly/REF export factor 0.308842
ST7L suppression of tumorigenicity 7 like 0.30848
HK2 hexokinase 2 0.308118
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.30631
TFPI2 tissue factor pathway inhibitor 2 0.304142
CDAN1 codanin 1 0.303059
SCRT1 scratch family zinc finger 1 0.301254
POLB polymerase (DNA directed), beta 0.299452
FAP fibroblast activation protein, alpha 0.299092
MXI1 MAX interactor 1, dimerization protein 0.295851
DSC2 desmocollin 2 0.295851
KRT19 keratin 19, type I 0.295132
LATS2 large tumor suppressor kinase 2 0.294413
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.294053
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.292975
PPP4C protein phosphatase 4, catalytic subunit 0.292257
HK3 hexokinase 3 (white cell) 0.290462
HABP4 hyaluronan binding protein 4 0.290103
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 0.289386
MCM2 minichromosome maintenance complex component 2 0.287952
FOXR1 forkhead box R1 0.286877
FGF19 fibroblast growth factor 19 0.286519
WNT2B wingless-type MMTV integration site family, member 2B 0.285802
LAPTM4B lysosomal protein transmembrane 4 beta 0.285802
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.285086
FGF1 fibroblast growth factor 1 (acidic) 0.284728
EEF2 eukaryotic translation elongation factor 2 0.284013
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.283297
MIR27B microRNA 27b 0.28294
CSAG2 CSAG family, member 2 0.281868
CSAG3 CSAG family, member 3 0.281868
AURKB aurora kinase B 0.281868
ANO3 anoctamin 3 0.279724
CDX4 caudal type homeobox 4 0.279367
RAD51 RAD51 recombinase 0.278297
DNTT DNA nucleotidylexotransferase 0.274732
HOXC9 homeobox C9 0.274021
PTCH2 patched 2 0.273308
EPCAM epithelial cell adhesion molecule 0.272953
MIXL1 Mix paired-like homeobox 0.272597
RPSA ribosomal protein SA 0.272241
MAGEB1 melanoma antigen family B1 0.27153
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.271174
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.270819
MLH1 mutL homolog 1 0.270464
NMT2 N-myristoyltransferase 2 0.269753
MIR31 microRNA 31 0.269043
IL15RA interleukin 15 receptor, alpha 0.268687
ERBB3 erb-b2 receptor tyrosine kinase 3 0.268687
MT2A metallothionein 2A 0.268687
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.266913
SHH sonic hedgehog 0.266558
MUC4 mucin 4, cell surface associated 0.266203
MIR25 microRNA 25 0.264785
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.261599
HDGF hepatoma-derived growth factor 0.260538
HHIP hedgehog interacting protein 0.259477
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.257711
GPX3 glutathione peroxidase 3 0.256652
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 0.256652
ANKRD6 ankyrin repeat domain 6 0.256652
KIF22 kinesin family member 22 0.256299
ZHX2 zinc fingers and homeoboxes 2 0.256299
DAP death-associated protein 0.255241
CRIP1 cysteine-rich protein 1 (intestinal) 0.255241
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.254183
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.253479
CTTN cortactin 0.251718
FGF2 fibroblast growth factor 2 (basic) 0.250663
HOXC5 homeobox C5 0.250311
NQO1 NAD(P)H dehydrogenase, quinone 1 0.248905
CDK6 cyclin-dependent kinase 6 0.246448
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.246098
MAP7 microtubule-associated protein 7 0.244696
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.244345
GSK3B glycogen synthase kinase 3 beta 0.243995
ZNF217 zinc finger protein 217 0.243645
RAD23B RAD23 homolog B (S. cerevisiae) 0.242595
EPB42 erythrocyte membrane protein band 4.2 0.239799
PPCS phosphopantothenoylcysteine synthetase 0.238752
AFP alpha-fetoprotein 0.237009
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.235268
NOTCH1 notch 1 0.234573
NKD2 naked cuticle homolog 2 (Drosophila) 0.234573
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.234573
CCND2 cyclin D2 0.234225
FOS FBJ murine osteosarcoma viral oncogene homolog 0.233878
WNT11 wingless-type MMTV integration site family, member 11 0.231795
MCRS1 microspherule protein 1 0.231102
IGFBP3 insulin-like growth factor binding protein 3 0.230409
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.229716
LDOC1 leucine zipper, down-regulated in cancer 1 0.229716
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 0.229716
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.22937
FADD Fas (TNFRSF6)-associated via death domain 0.228679
WASL Wiskott-Aldrich syndrome-like 0.228333
TAPBP TAP binding protein (tapasin) 0.228333
ZEB1 zinc finger E-box binding homeobox 1 0.228333
WNT10B wingless-type MMTV integration site family, member 10B 0.225917
S100A8 S100 calcium binding protein A8 0.223165
LDHB lactate dehydrogenase B 0.223165
RHOU ras homolog family member U 0.223165
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.222822
CD24 CD24 molecule 0.222479
TENM2 teneurin transmembrane protein 2 0.221793
NUDC nudC nuclear distribution protein 0.221108
RPL14 ribosomal protein L14 0.221108
IFNA5 interferon, alpha 5 0.219398
ANO2 anoctamin 2, calcium activated chloride channel 0.219057
AZIN1 antizyme inhibitor 1 0.218374
PDGFB platelet-derived growth factor beta polypeptide 0.218374
MSH3 mutS homolog 3 0.217352
CXCL3 chemokine (C-X-C motif) ligand 3 0.217352
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.215992
GADD45G growth arrest and DNA-damage-inducible, gamma 0.214297
MSH2 mutS homolog 2 0.213959
POLK polymerase (DNA directed) kappa 0.213621
CENPH centromere protein H 0.213283
TPM2 tropomyosin 2 (beta) 0.213283
H2AFX H2A histone family, member X 0.213283
DEPDC1 DEP domain containing 1 0.212271
TM4SF5 transmembrane 4 L six family member 5 0.211261
FAT2 FAT atypical cadherin 2 0.211261
SFN stratifin 0.210589
HOXB7 homeobox B7 0.210253
FGFR1 fibroblast growth factor receptor 1 0.209918
FASN fatty acid synthase 0.209583
FGF8 fibroblast growth factor 8 (androgen-induced) 0.208914
IGF2 insulin-like growth factor 2 0.207912
NONO non-POU domain containing, octamer-binding 0.207245
BIRC2 baculoviral IAP repeat containing 2 0.206913
MYCBP MYC binding protein 0.206248
GPX1 glutathione peroxidase 1 0.204263
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.203933
HBA2 hemoglobin, alpha 2 0.203275
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.202946
PRICKLE2 prickle homolog 2 (Drosophila) 0.20229
SUGP1 SURP and G patch domain containing 1 0.20229
HELZ helicase with zinc finger 0.201962
CD80 CD80 molecule 0.201635
KRT8 keratin 8, type II 0.201308
EBF2 early B-cell factor 2 0.200331
EFNA4 ephrin-A4 0.200006
PRTN3 proteinase 3 0.198709
KLF4 Kruppel-like factor 4 (gut) 0.197742
PTHLH parathyroid hormone-like hormone 0.196779
FGF12 fibroblast growth factor 12 0.196779
MCM7 minichromosome maintenance complex component 7 0.195183
KIF27 kinesin family member 27 0.194548
FTL ferritin, light polypeptide 0.193915
FTH1 ferritin, heavy polypeptide 1 0.193915
GPR39 G protein-coupled receptor 39 0.1936
MIR100 microRNA 100 0.192031
DIABLO diablo, IAP-binding mitochondrial protein 0.192031
SSRP1 structure specific recognition protein 1 0.192031
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.190786
FN1 fibronectin 1 0.190476
FAT3 FAT atypical cadherin 3 0.190476
GSTM3 glutathione S-transferase mu 3 (brain) 0.190168
PF4V1 platelet factor 4 variant 1 0.190168
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.189859
PPARG peroxisome proliferator-activated receptor gamma 0.189551
CSTB cystatin B (stefin B) 0.189244
ADIPOR2 adiponectin receptor 2 0.188022
EMP3 epithelial membrane protein 3 0.187113
ZEB2 zinc finger E-box binding homeobox 2 0.187113
CSNK1E casein kinase 1, epsilon 0.18651
CPSF3L cleavage and polyadenylation specific factor 3-like 0.18621
RAD54B RAD54 homolog B (S. cerevisiae) 0.185313
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.18472
MIR10B microRNA 10b 0.18472
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.18472
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.184424
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.184128
MT1H metallothionein 1H 0.183541
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 0.183541
XPA xeroderma pigmentosum, complementation group A 0.183248
FCGBP Fc fragment of IgG binding protein 0.182957
HBA1 hemoglobin, alpha 1 0.181222
AKR1C2 aldo-keto reductase family 1, member C2 0.180652
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.180652
CYR61 cysteine-rich, angiogenic inducer, 61 0.180084
H3F3A H3 histone, family 3A 0.17952
H3F3B H3 histone, family 3B (H3.3B) 0.17952
PER1 period circadian clock 1 0.179239
PDLIM2 PDZ and LIM domain 2 (mystique) 0.17896
CBR3 carbonyl reductase 3 0.178682
NMUR2 neuromedin U receptor 2 0.178682
S100A14 S100 calcium binding protein A14 0.178403
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.178126
CSTA cystatin A (stefin A) 0.177851
DEGS1 delta(4)-desaturase, sphingolipid 1 0.177576
CCDC88A coiled-coil domain containing 88A 0.176757
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.176757
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.176215
PCCA propionyl CoA carboxylase, alpha polypeptide 0.176215
PLCD1 phospholipase C, delta 1 0.175411
KIF7 kinesin family member 7 0.175146
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.174617
MAGEC1 melanoma antigen family C1 0.174093
MMP11 matrix metallopeptidase 11 0.173571
ANXA10 annexin A10 0.173314
GP6 glycoprotein VI (platelet) 0.173057
RPL7 ribosomal protein L7 0.172799
STOML2 stomatin (EPB72)-like 2 0.172291
S100A10 S100 calcium binding protein A10 0.172038
SFRP1 secreted frizzled-related protein 1 0.171785
TIMP1 TIMP metallopeptidase inhibitor 1 0.171785
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 0.171286
PCTP phosphatidylcholine transfer protein 0.171286
S100A2 S100 calcium binding protein A2 0.171036
NRG4 neuregulin 4 0.170544
FOXM1 forkhead box M1 0.170544
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.169812
INCENP inner centromere protein antigens 135/155kDa 0.169091
ADIPOR1 adiponectin receptor 1 0.168381
MTNR1A melatonin receptor 1A 0.168381
MAGEA9B melanoma antigen family A9B 0.168148
MAGEA9 melanoma antigen family A9 0.168148
STMN1 stathmin 1 0.168148
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.167224
DSG1 desmoglein 1 0.166768
HOXC4 homeobox C4 0.166544
TRADD TNFRSF1A-associated via death domain 0.166544
SSTR3 somatostatin receptor 3 0.166095
DAAM2 dishevelled associated activator of morphogenesis 2 0.165874
TUBE1 tubulin, epsilon 1 0.165217
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.165217
MAGEA6 melanoma antigen family A6 0.165001
SRSF1 serine/arginine-rich splicing factor 1 0.164571
CXCR2 chemokine (C-X-C motif) receptor 2 0.163523
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.163523
PLAUR plasminogen activator, urokinase receptor 0.162505
CHEK1 checkpoint kinase 1 0.162306
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.162109
EFNA2 ephrin-A2 0.161139
CDK2 cyclin-dependent kinase 2 0.161139
HSPA4 heat shock 70kDa protein 4 0.160387
RAD54L RAD54-like (S. cerevisiae) 0.160203
RPL3 ribosomal protein L3 0.160021
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.159838
CDC25C cell division cycle 25C 0.159302
PDGFA platelet-derived growth factor alpha polypeptide 0.158778
EBAG9 estrogen receptor binding site associated, antigen, 9 0.158097
CD86 CD86 molecule 0.157602
CHEK2 checkpoint kinase 2 0.157602
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.144922
SFRP2 secreted frizzled-related protein 2 0.14456
TAGLN2 transgelin 2 0.144518
CDH20 cadherin 20, type 2 0.143225
RAB11A RAB11A, member RAS oncogene family 0.142777
AXIN1 axin 1 0.142218
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.14217
NUMB numb homolog (Drosophila) 0.141299
NEIL2 nei endonuclease VIII-like 2 (E. coli) 0.140364
MUC7 mucin 7, secreted 0.140295
MUC3A mucin 3A, cell surface associated 0.140267
CNTLN centlein, centrosomal protein 0.139974
MIR215 microRNA 215 0.1399
SFRP5 secreted frizzled-related protein 5 0.139892
CXCL14 chemokine (C-X-C motif) ligand 14 0.139892
RARG retinoic acid receptor, gamma 0.13984
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.139771
CARD9 caspase recruitment domain family, member 9 0.139687
EVPL envoplakin 0.139663
CGB7 chorionic gonadotropin, beta polypeptide 7 0.139408
CGB5 chorionic gonadotropin, beta polypeptide 5 0.139375
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.139089
LEPR leptin receptor 0.13902
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 0.138879
CGB chorionic gonadotropin, beta polypeptide 0.138825
CGB8 chorionic gonadotropin, beta polypeptide 8 0.138811
EPS8 epidermal growth factor receptor pathway substrate 8 0.138743
SCO1 SCO1 cytochrome c oxidase assembly protein 0.138725
CYTL1 cytokine-like 1 0.138642
RFC3 replication factor C (activator 1) 3, 38kDa 0.138105
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.137678
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.137629
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.137465
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.136917
GNLY granulysin 0.136275
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.13617
FOXN1 forkhead box N1 0.135867
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.13584
LY75 lymphocyte antigen 75 0.135416
AMACR alpha-methylacyl-CoA racemase 0.135358
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.135247
MYDGF myeloid-derived growth factor 0.135196
SNRPN small nuclear ribonucleoprotein polypeptide N 0.134947
SULF2 sulfatase 2 0.134658
PTF1A pancreas specific transcription factor, 1a 0.134538
RAB3D RAB3D, member RAS oncogene family 0.134359
CLDN4 claudin 4 0.133878
CCNE1 cyclin E1 0.131331
SFRP4 secreted frizzled-related protein 4 0.130229
GYPE glycophorin E (MNS blood group) 0.130129
WIF1 WNT inhibitory factor 1 0.128033
EIF4E eukaryotic translation initiation factor 4E 0.126531
AXIN2 axin 2 0.126447
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.12216
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.12013
APC adenomatous polyposis coli 0.120034
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.119488
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.11788
TPM1 tropomyosin 1 (alpha) 0.117002
TACR3 tachykinin receptor 3 0.116437
DUSP6 dual specificity phosphatase 6 0.116409
REEP5 receptor accessory protein 5 0.116266
TMEM51 transmembrane protein 51 0.116237
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 0.11612
PLA2G10 phospholipase A2, group X 0.116091
RPS15 ribosomal protein S15 0.115683
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.115418
HNF1B HNF1 homeobox B 0.115298
RBBP8 retinoblastoma binding protein 8 0.114697
KAT5 K(lysine) acetyltransferase 5 0.114636
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.114356
FKBP6 FK506 binding protein 6, 36kDa 0.114263
EGR3 early growth response 3 0.113702
NLN neurolysin (metallopeptidase M3 family) 0.113127
BCL10 B-cell CLL/lymphoma 10 0.112837
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.112442
RUNX2 runt-related transcription factor 2 0.112442
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.111744
GPBAR1 G protein-coupled bile acid receptor 1 0.111133
MMP13 matrix metallopeptidase 13 0.111031
LAMC2 laminin, gamma 2 0.110822
FZD10 frizzled class receptor 10 0.110822
GSTM5 glutathione S-transferase mu 5 0.110822
TACR2 tachykinin receptor 2 0.110752
CKS2 CDC28 protein kinase regulatory subunit 2 0.110017
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.109981
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.109874
ETV1 ets variant 1 0.109838
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.109766
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.10973
IL20RB interleukin 20 receptor beta 0.109443
ATR ATR serine/threonine kinase 0.108493
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.108308
MIR185 microRNA 185 0.107481
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.107405
MIR223 microRNA 223 0.106442
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.10613
EBF1 early B-cell factor 1 0.105936
CLDN3 claudin 3 0.105696
PCDH10 protocadherin 10 0.105656
SCGB2A1 secretoglobin, family 2A, member 1 0.105256
AICDA activation-induced cytidine deaminase 0.105136
MMP28 matrix metallopeptidase 28 0.104976
ONECUT3 one cut homeobox 3 0.104857
PYY peptide YY 0.10453
CALD1 caldesmon 1 0.10453
ALLC allantoicase 0.104407
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.10416
PGC progastricsin (pepsinogen C) 0.103669
BBS5 Bardet-Biedl syndrome 5 0.103459
TAC1 tachykinin, precursor 1 0.10329
PTGDR prostaglandin D2 receptor (DP) 0.103038
CLEC11A C-type lectin domain family 11, member A 0.102912
RAD18 RAD18 E3 ubiquitin protein ligase 0.102786
SCGB1D1 secretoglobin, family 1D, member 1 0.102702
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.102534
HDAC1 histone deacetylase 1 0.102406
GATA6 GATA binding protein 6 0.10219
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.102147
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.101888
IL2RA interleukin 2 receptor, alpha 0.101544
ARTN artemin 0.101109
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.100889
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 0.100801
GATA4 GATA binding protein 4 0.100801
RBM15 RNA binding motif protein 15 0.100756
LMX1B LIM homeobox transcription factor 1, beta 0.100712
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.100448
HK1 hexokinase 1 0.100404
HES5 hes family bHLH transcription factor 5 0.100316
HAT1 histone acetyltransferase 1 0.100316
INHBA inhibin, beta A 0.100051
PERP PERP, TP53 apoptosis effector 0.099781
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.099735
CD83 CD83 molecule 0.099645
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 0.099465
ADCY1 adenylate cyclase 1 (brain) 0.099374
GML glycosylphosphatidylinositol anchored molecule like 0.098834
RELN reelin 0.098465
COL4A2 collagen, type IV, alpha 2 0.098235
TSPO translocator protein (18kDa) 0.09782
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.096979
ETV4 ets variant 4 0.096979
NCOA3 nuclear receptor coactivator 3 0.096697
GSTZ1 glutathione S-transferase zeta 1 0.095939
ITGA6 integrin, alpha 6 0.095842
SSX4 synovial sarcoma, X breakpoint 4 0.095842
SSX4B synovial sarcoma, X breakpoint 4B 0.095842
PADI4 peptidyl arginine deiminase, type IV 0.095362
IL22RA1 interleukin 22 receptor, alpha 1 0.095218