esophageal cancer cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

348 proteins co-occuring with the tissue esophageal cancer cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.21985
SLC44A3 solute carrier family 44, member 3 1.93311
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 1.57356
C16ORF62 chromosome 16 open reading frame 62 1.52426
DEC1 deleted in esophageal cancer 1 1.33048
TNRC6C trinucleotide repeat containing 6C 1.30523
WDR66 WD repeat domain 66 1.24833
RGS22 regulator of G-protein signaling 22 1.18645
AFAP1 actin filament associated protein 1 1.10137
TP53 tumor protein p53 1.09562
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 1.09385
EGFR epidermal growth factor receptor 1.05633
FBXL19 F-box and leucine-rich repeat protein 19 1.02162
CCND1 cyclin D1 1.01637
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.936629
CCDC110 coiled-coil domain containing 110 0.930193
LDOC1 leucine zipper, down-regulated in cancer 1 0.917779
MDC1 mediator of DNA-damage checkpoint 1 0.902424
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.898595
PLCE1 phospholipase C, epsilon 1 0.881627
RBM38 RNA binding motif protein 38 0.875284
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.868529
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 0.864312
RARB retinoic acid receptor, beta 0.859679
HABP4 hyaluronan binding protein 4 0.857153
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.853368
HOOK2 hook microtubule-tethering protein 2 0.835737
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.834899
HNF4A hepatocyte nuclear factor 4, alpha 0.833223
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.825686
ERBB2 erb-b2 receptor tyrosine kinase 2 0.81983
SKP1 S-phase kinase-associated protein 1 0.809803
KRT4 keratin 4, type II 0.798125
CDKN2A cyclin-dependent kinase inhibitor 2A 0.796041
CDX2 caudal type homeobox 2 0.795208
CCNL2 cyclin L2 0.792709
BTG1 B-cell translocation gene 1, anti-proliferative 0.758259
SHROOM2 shroom family member 2 0.738442
BNC2 basonuclin 2 0.738442
MIR21 microRNA 21 0.737618
VPRBP Vpr (HIV-1) binding protein 0.737618
WNT9B wingless-type MMTV integration site family, member 9B 0.727741
CENPF centromere protein F, 350/400kDa 0.725685
FHIT fragile histidine triad 0.725274
BIRC5 baculoviral IAP repeat containing 5 0.723631
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.72322
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.722809
KDM4C lysine (K)-specific demethylase 4C 0.718292
SUSD2 sushi domain containing 2 0.714189
FNBP1 formin binding protein 1 0.703536
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 0.659897
GML glycosylphosphatidylinositol anchored molecule like 0.657866
HOXA13 homeobox A13 0.65746
TENM2 teneurin transmembrane protein 2 0.6534
MMP21 matrix metallopeptidase 21 0.652994
ANXA5 annexin A5 0.647316
RBBP6 retinoblastoma binding protein 6 0.646505
PDE4DIP phosphodiesterase 4D interacting protein 0.642048
KIF22 kinesin family member 22 0.639214
CCNB1 cyclin B1 0.631527
BECN1 beclin 1, autophagy related 0.627485
HELZ helicase with zinc finger 0.621831
HOXC5 homeobox C5 0.613361
PRDX1 peroxiredoxin 1 0.604502
WNT3 wingless-type MMTV integration site family, member 3 0.602088
NRD1 nardilysin (N-arginine dibasic convertase) 0.600479
NKD2 naked cuticle homolog 2 (Drosophila) 0.600479
HDAC10 histone deacetylase 10 0.597666
GRB7 growth factor receptor-bound protein 7 0.589635
LYPD3 LY6/PLAUR domain containing 3 0.589234
DGCR8 DGCR8 microprocessor complex subunit 0.586026
DROSHA drosha, ribonuclease type III 0.571219
KDM4B lysine (K)-specific demethylase 4B 0.571219
KRT6B keratin 6B, type II 0.562042
BAX BCL2-associated X protein 0.561644
GPX7 glutathione peroxidase 7 0.550503
LTBP4 latent transforming growth factor beta binding protein 4 0.549709
TFPI2 tissue factor pathway inhibitor 2 0.546136
SPRR3 small proline-rich protein 3 0.545342
WNT10A wingless-type MMTV integration site family, member 10A 0.542963
WNT7B wingless-type MMTV integration site family, member 7B 0.542566
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.540981
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.521223
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.518072
MIR185 microRNA 185 0.516497
CDH13 cadherin 13 0.50471
ARHGAP5 Rho GTPase activating protein 5 0.503926
GADD45B growth arrest and DNA-damage-inducible, beta 0.503533
HOXC9 homeobox C9 0.499615
GADD45A growth arrest and DNA-damage-inducible, alpha 0.496092
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.493354
RRM1 ribonucleotide reductase M1 0.491791
CAPNS1 calpain, small subunit 1 0.491791
SCGB3A1 secretoglobin, family 3A, member 1 0.488276
CTHRC1 collagen triple helix repeat containing 1 0.482817
MTUS1 microtubule associated tumor suppressor 1 0.481648
MAPK1 mitogen-activated protein kinase 1 0.479312
AURKA aurora kinase A 0.471539
WNT2 wingless-type MMTV integration site family member 2 0.471539
CBR3 carbonyl reductase 3 0.468436
FRK fyn-related Src family tyrosine kinase 0.468436
WNT8A wingless-type MMTV integration site family, member 8A 0.464561
ONECUT3 one cut homeobox 3 0.4634
MCM6 minichromosome maintenance complex component 6 0.462239
HOXC4 homeobox C4 0.456828
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.455284
RAD51 RAD51 recombinase 0.43989
SIAE sialic acid acetylesterase 0.43989
MIR25 microRNA 25 0.437205
SFN stratifin 0.435672
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.434906
OSR2 odd-skipped related transciption factor 2 0.432608
SURF1 surfeit 1 0.432225
STC2 stanniocalcin 2 0.428018
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.428018
DOCK8 dedicator of cytokinesis 8 0.426872
FSCN3 fascin actin-bundling protein 3, testicular 0.424963
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.424963
PEBP1 phosphatidylethanolamine binding protein 1 0.42191
CDK6 cyclin-dependent kinase 6 0.419242
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.415814
SMAD3 SMAD family member 3 0.413532
FSCN2 fascin actin-bundling protein 2, retinal 0.412391
SRSF1 serine/arginine-rich splicing factor 1 0.410111
IGFBP3 insulin-like growth factor binding protein 3 0.404797
SOX17 SRY (sex determining region Y)-box 17 0.402144
RALB v-ral simian leukemia viral oncogene homolog B 0.401007
HOXB9 homeobox B9 0.393442
GCAT glycine C-acetyltransferase 0.390421
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.38665
CYBRD1 cytochrome b reductase 1 0.384013
C1QBP complement component 1, q subcomponent binding protein 0.380627
NOTCH1 notch 1 0.380251
GPR39 G protein-coupled receptor 39 0.379123
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.376494
MIR27B microRNA 27b 0.376494
MIRLET7C microRNA let-7c 0.376119
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.374618
TTN titin 0.374618
AXL AXL receptor tyrosine kinase 0.371245
WNT8B wingless-type MMTV integration site family, member 8B 0.369373
CTAG2 cancer/testis antigen 2 0.36825
CLDN6 claudin 6 0.367502
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.360409
HRAS Harvey rat sarcoma viral oncogene homolog 0.358174
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.356686
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 0.356314
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.356314
CAPN10 calpain 10 0.355198
CDC5L cell division cycle 5-like 0.351856
AKAP12 A kinase (PRKA) anchor protein 12 0.351114
H2AFX H2A histone family, member X 0.34963
FZD5 frizzled class receptor 5 0.348519
WNT5B wingless-type MMTV integration site family, member 5B 0.347778
MMP26 matrix metallopeptidase 26 0.344079
RUNX3 runt-related transcription factor 3 0.34371
HOXC6 homeobox C6 0.342602
MIR192 microRNA 192 0.341126
XAF1 XIAP associated factor 1 0.341126
PTK6 protein tyrosine kinase 6 0.340019
HOXD10 homeobox D10 0.340019
INHBA inhibin, beta A 0.340019
FOXH1 forkhead box H1 0.337808
MIR10B microRNA 10b 0.337072
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.337072
OPN3 opsin 3 0.336704
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.333028
GAST gastrin 0.33156
HMX2 H6 family homeobox 2 0.331194
IVL involucrin 0.330094
S1PR5 sphingosine-1-phosphate receptor 5 0.326798
LAMC2 laminin, gamma 2 0.320227
HOXC8 homeobox C8 0.319863
MIRLET7B microRNA let-7b 0.317679
NDN necdin, melanoma antigen (MAGE) family member 0.312957
SOX18 SRY (sex determining region Y)-box 18 0.310783
FTCD formimidoyltransferase cyclodeaminase 0.308974
IGHV3-30 immunoglobulin heavy variable 3-30 0.308974
FZD7 frizzled class receptor 7 0.306444
ASCL2 achaete-scute family bHLH transcription factor 2 0.304279
ATG5 autophagy related 5 0.301758
BMP6 bone morphogenetic protein 6 0.301398
LEP leptin 0.300679
VEGFC vascular endothelial growth factor C 0.299242
FGF6 fibroblast growth factor 6 0.29673
GSK3B glycogen synthase kinase 3 beta 0.294581
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.291008
SCGB1D1 secretoglobin, family 1D, member 1 0.289939
GATA5 GATA binding protein 5 0.288158
JUN jun proto-oncogene 0.284962
TDG thymine-DNA glycosylase 0.283899
WISP1 WNT1 inducible signaling pathway protein 1 0.281423
GJB2 gap junction protein, beta 2, 26kDa 0.276846
ETV1 ets variant 1 0.275444
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.275444
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.274045
ZIC2 Zic family member 2 0.271256
HDGF hepatoma-derived growth factor 0.269521
TYMS thymidylate synthetase 0.264353
LATS2 large tumor suppressor kinase 2 0.263669
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.263669
MAGEC1 melanoma antigen family C1 0.261284
JAK2 Janus kinase 2 0.256902
DSC2 desmocollin 2 0.253248
NCSTN nicastrin 0.252261
WNT6 wingless-type MMTV integration site family, member 6 0.251606
GADD45G growth arrest and DNA-damage-inducible, gamma 0.251279
S100A4 S100 calcium binding protein A4 0.250301
PCCA propionyl CoA carboxylase, alpha polypeptide 0.249329
FSCN1 fascin actin-bundling protein 1 0.24676
DICER1 dicer 1, ribonuclease type III 0.246442
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.246124
VEGFA vascular endothelial growth factor A 0.245491
TFRC transferrin receptor 0.244545
HOXA2 homeobox A2 0.243918
EPCAM epithelial cell adhesion molecule 0.240826
PDPK1 3-phosphoinositide dependent protein kinase 1 0.23961
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.239307
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.236627
C19ORF48 chromosome 19 open reading frame 48 0.234302
IGF1R insulin-like growth factor 1 receptor 0.234302
SYNE1 spectrin repeat containing, nuclear envelope 1 0.233446
TYRO3 TYRO3 protein tyrosine kinase 0.232599
TIMP3 TIMP metallopeptidase inhibitor 3 0.23176
PARP1 poly (ADP-ribose) polymerase 1 0.230931
WNT2B wingless-type MMTV integration site family, member 2B 0.23011
KLF4 Kruppel-like factor 4 (gut) 0.229299
PPARG peroxisome proliferator-activated receptor gamma 0.229032
PTEN phosphatase and tensin homolog 0.228764
LEPR leptin receptor 0.228234
CXCL3 chemokine (C-X-C motif) ligand 3 0.227186
HSPA8 heat shock 70kDa protein 8 0.223906
CAV1 caveolin 1, caveolae protein, 22kDa 0.223662
MSH3 mutS homolog 3 0.222699
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.219707
CCND2 cyclin D2 0.218398
CIAO1 cytosolic iron-sulfur assembly component 1 0.217974
FLOT1 flotillin 1 0.217974
MTA1 metastasis associated 1 0.216933
PDGFRL platelet-derived growth factor receptor-like 0.215928
BCL2 B-cell CLL/lymphoma 2 0.215341
RET ret proto-oncogene 0.214388
MT3 metallothionein 3 0.213291
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.184649
SOD2 superoxide dismutase 2, mitochondrial 0.178264
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.177808
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.177139
ARF1 ADP-ribosylation factor 1 0.175467
FBXO32 F-box protein 32 0.173782
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.171302
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.17115
CCNA1 cyclin A1 0.170712
SFRP2 secreted frizzled-related protein 2 0.166894
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.166198
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.16471
ANO1 anoctamin 1, calcium activated chloride channel 0.164146
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.164002
SIX1 SIX homeobox 1 0.162828
YY1 YY1 transcription factor 0.162631
AURKB aurora kinase B 0.161531
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.160273
ERCC1 excision repair cross-complementation group 1 0.156848
SPHK1 sphingosine kinase 1 0.15448
NCR1 natural cytotoxicity triggering receptor 1 0.14897
CDK1 cyclin-dependent kinase 1 0.146769
CMKLR1 chemerin chemokine-like receptor 1 0.144477
SMAD4 SMAD family member 4 0.143751
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.1367
CDK2 cyclin-dependent kinase 2 0.136414
MAPK3 mitogen-activated protein kinase 3 0.135924
ZEB2 zinc finger E-box binding homeobox 2 0.133592
MECOM MDS1 and EVI1 complex locus 0.132033
KLF10 Kruppel-like factor 10 0.131118
KIAA0101 KIAA0101 0.125587
HBD hemoglobin, delta 0.125197
FGF7 fibroblast growth factor 7 0.124937
KRAS Kirsten rat sarcoma viral oncogene homolog 0.121267
LAP3 leucine aminopeptidase 3 0.121233
CXCL2 chemokine (C-X-C motif) ligand 2 0.120757
FGFR2 fibroblast growth factor receptor 2 0.119317
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.117128
FGF8 fibroblast growth factor 8 (androgen-induced) 0.116173
CSN2 casein beta 0.115608
TOP2A topoisomerase (DNA) II alpha 170kDa 0.115149
DDIT3 DNA-damage-inducible transcript 3 0.115113
HBB hemoglobin, beta 0.115077
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.114611
S1PR3 sphingosine-1-phosphate receptor 3 0.114324
DSC3 desmocollin 3 0.11411
FASLG Fas ligand (TNF superfamily, member 6) 0.111691
FBN2 fibrillin 2 0.111111
BEST1 bestrophin 1 0.110817
S1PR2 sphingosine-1-phosphate receptor 2 0.110743
CUL1 cullin 1 0.110229
GPX2 glutathione peroxidase 2 0.110009
CD24 CD24 molecule 0.109825
THBS2 thrombospondin 2 0.109679
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.108943
RELN reelin 0.108571
DMBT1 deleted in malignant brain tumors 1 0.108348
FGF2 fibroblast growth factor 2 (basic) 0.108348
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.108237
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.107977
TCL1A T-cell leukemia/lymphoma 1A 0.107643
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 0.107458
MMP7 matrix metallopeptidase 7 0.107421
SREBF1 sterol regulatory element binding transcription factor 1 0.106675
PTGDR prostaglandin D2 receptor (DP) 0.106112
GSTM2 glutathione S-transferase mu 2 (muscle) 0.105887
ATOH1 atonal homolog 1 (Drosophila) 0.10585
KRT5 keratin 5, type II 0.105587
ERBB3 erb-b2 receptor tyrosine kinase 3 0.1054
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.105064
CCL20 chemokine (C-C motif) ligand 20 0.10355
TBX1 T-box 1 0.103437
HPGDS hematopoietic prostaglandin D synthase 0.102297
SP1 Sp1 transcription factor 0.102144
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.100503
GSTA4 glutathione S-transferase alpha 4 0.10008
ETV4 ets variant 4 0.099389
MCM7 minichromosome maintenance complex component 7 0.099274
FGFR1 fibroblast growth factor receptor 1 0.09889
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.098852
PRSS3 protease, serine, 3 0.098273
FOS FBJ murine osteosarcoma viral oncogene homolog 0.098195
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.096379
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.095834
ATM ATM serine/threonine kinase 0.095601
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.095445
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.095406
S1PR1 sphingosine-1-phosphate receptor 1 0.095173
KRT14 keratin 14, type I 0.095135
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.095096
CXCL9 chemokine (C-X-C motif) ligand 9 0.094863
ADIPOR2 adiponectin receptor 2 0.094863
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.094085
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.093577
MUC4 mucin 4, cell surface associated 0.093538
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.093148
ATF3 activating transcription factor 3 0.092174
ADORA2A adenosine A2a receptor 0.091938
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.091742
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.091625
KRT8 keratin 8, type II 0.091194
ADIPOR1 adiponectin receptor 1 0.090881
FBP1 fructose-1,6-bisphosphatase 1 0.089392
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.088528
NOTCH3 notch 3 0.088372