esculin-3052 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the esculin-3052 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADAM28 ADAM metallopeptidase domain 28
ALPL alkaline phosphatase, liver/bone/kidney
AMBP alpha-1-microglobulin/bikunin precursor
ANGPT2 angiopoietin 2
ANGPTL2 angiopoietin-like 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGAP26 Rho GTPase activating protein 26
BCL2 B-cell CLL/lymphoma 2
BGN biglycan
BMP15 bone morphogenetic protein 15
C10ORF12 chromosome 10 open reading frame 12
C1ORF61 chromosome 1 open reading frame 61
C3ORF52 chromosome 3 open reading frame 52
CCL22 chemokine (C-C motif) ligand 22
CD248 CD248 molecule, endosialin
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLIC2 chloride intracellular channel 2
COL10A1 collagen, type X, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COPE coatomer protein complex, subunit epsilon
CSHL1 chorionic somatomammotropin hormone-like 1
CUEDC1 CUE domain containing 1
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DMP1 dentin matrix acidic phosphoprotein 1
DUSP4 dual specificity phosphatase 4
EGLN3 egl-9 family hypoxia-inducible factor 3
EHD2 EH-domain containing 2
ELN elastin
ELSPBP1 epididymal sperm binding protein 1
EYA2 EYA transcriptional coactivator and phosphatase 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFR2 fibroblast growth factor receptor 2
FMO1 flavin containing monooxygenase 1
FOXO1 forkhead box O1
FUBP1 far upstream element (FUSE) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAL3ST4 galactose-3-O-sulfotransferase 4
GJA9 gap junction protein, alpha 9, 59kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAS GNAS complex locus
GRHL2 grainyhead-like 2 (Drosophila)
HEMK1 HemK methyltransferase family member 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HR hair growth associated
HRASLS2 HRAS-like suppressor 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL36RN interleukin 36 receptor antagonist
KAT8 K(lysine) acetyltransferase 8
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KNG1 kininogen 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC57399 uncharacterized gastric protein ZA52P
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP1 low density lipoprotein receptor-related protein 1
LRRC8E leucine rich repeat containing 8 family, member E
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MDK midkine (neurite growth-promoting factor 2)
MEIS3P1 Meis homeobox 3 pseudogene 1
MFAP3L microfibrillar-associated protein 3-like
MYOZ2 myozenin 2
NEU3 sialidase 3 (membrane sialidase)
NEUROG2 neurogenin 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRP1 neuropilin 1
NTM neurotrimin
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PDGFB platelet-derived growth factor beta polypeptide
PKNOX2 PBX/knotted 1 homeobox 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RERE arginine-glutamic acid dipeptide (RE) repeats
RNF186 ring finger protein 186
ROM1 retinal outer segment membrane protein 1
RRBP1 ribosome binding protein 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
STEAP4 STEAP family member 4
STX11 syntaxin 11
SYNE2 spectrin repeat containing, nuclear envelope 2
TACR1 tachykinin receptor 1
TBX5 T-box 5
TMOD1 tropomodulin 1
TMPRSS6 transmembrane protease, serine 6
TNP2 transition protein 2 (during histone to protamine replacement)
UPK2 uroplakin 2
VSIG10 V-set and immunoglobulin domain containing 10
WTAP Wilms tumor 1 associated protein
ZER1 zyg-11 related, cell cycle regulator
ZNF235 zinc finger protein 235
ZNF276 zinc finger protein 276
ZNF287 zinc finger protein 287
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
AXIN1 axin 1
C11ORF68 chromosome 11 open reading frame 68
C7ORF43 chromosome 7 open reading frame 43
C8A complement component 8, alpha polypeptide
C9ORF3 chromosome 9 open reading frame 3
C9ORF9 chromosome 9 open reading frame 9
CARF calcium responsive transcription factor
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD300C CD300c molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CELP carboxyl ester lipase pseudogene
CFAP69 cilia and flagella associated protein 69
COQ6 coenzyme Q6 monooxygenase
DPY19L1P1 DPY19L1 pseudogene 1
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ETAA1 Ewing tumor-associated antigen 1
FAM50B family with sequence similarity 50, member B
FBXO46 F-box protein 46
FGF23 fibroblast growth factor 23
FOXD1 forkhead box D1
FOXN2 forkhead box N2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GIF gastric intrinsic factor (vitamin B synthesis)
GIPC1 GIPC PDZ domain containing family, member 1
GPC3 glypican 3
HIST1H1B histone cluster 1, H1b
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AG histone cluster 1, H2ag
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
HOXB9 homeobox B9
IBSP integrin-binding sialoprotein
IL18 interleukin 18
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD7 potassium channel tetramerization domain containing 7
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1456 KIAA1456
LINC00597 long intergenic non-protein coding RNA 597
LRRC20 leucine rich repeat containing 20
METTL21B methyltransferase like 21B
MTERF4 mitochondrial transcription termination factor 4
MYO15A myosin XVA
NT5DC3 5'-nucleotidase domain containing 3
NTSR1 neurotensin receptor 1 (high affinity)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PKN1 protein kinase N1
PLTP phospholipid transfer protein
POMZP3 POM121 and ZP3 fusion
PRSS53 protease, serine, 53
RAB17 RAB17, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SALL2 spalt-like transcription factor 2
SGMS1 sphingomyelin synthase 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F5 solute carrier family 35, member F5
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TAGLN transgelin
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBKBP1 TBK1 binding protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM212 transmembrane protein 212
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPS1 trichorhinophalangeal syndrome I
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3D tubulin, alpha 3d
UPB1 ureidopropionase, beta
UPK3A uroplakin 3A
WASF3 WAS protein family, member 3
YOD1 YOD1 deubiquitinase
ZBTB6 zinc finger and BTB domain containing 6
ZNF10 zinc finger protein 10