erythromycin-6729 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the erythromycin-6729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APC2 adenomatosis polyposis coli 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BTN3A1 butyrophilin, subfamily 3, member A1
CCDC28B coiled-coil domain containing 28B
CCDC71 coiled-coil domain containing 71
CD82 CD82 molecule
CDC14A cell division cycle 14A
CDC42 cell division cycle 42
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLDN18 claudin 18
CLSPN claspin
CRHR1 corticotropin releasing hormone receptor 1
CST5 cystatin D
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DLC1 DLC1 Rho GTPase activating protein
DNAAF1 dynein, axonemal, assembly factor 1
DTNB dystrobrevin, beta
DUSP9 dual specificity phosphatase 9
EFHC2 EF-hand domain (C-terminal) containing 2
EFNB1 ephrin-B1
ELK1 ELK1, member of ETS oncogene family
EPS8L1 EPS8-like 1
FBLN1 fibulin 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GGT1 gamma-glutamyltransferase 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPR21 G protein-coupled receptor 21
GRIK5 glutamate receptor, ionotropic, kainate 5
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HAP1 huntingtin-associated protein 1
HHLA1 HERV-H LTR-associating 1
HIP1 huntingtin interacting protein 1
HIPK3 homeodomain interacting protein kinase 3
HIST1H3I histone cluster 1, H3i
IGFBP7 insulin-like growth factor binding protein 7
IL11 interleukin 11
ITGB6 integrin, beta 6
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KIAA1467 KIAA1467
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT38 keratin 38, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAPTM5 lysosomal protein transmembrane 5
LGALS8 lectin, galactoside-binding, soluble, 8
LYZ lysozyme
MEG3 maternally expressed 3 (non-protein coding)
MRPS18C mitochondrial ribosomal protein S18C
MS4A5 membrane-spanning 4-domains, subfamily A, member 5
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NEK9 NIMA-related kinase 9
NNMT nicotinamide N-methyltransferase
NRAP nebulin-related anchoring protein
NXPH4 neurexophilin 4
OMD osteomodulin
PALM paralemmin
PASK PAS domain containing serine/threonine kinase
PCDHB13 protocadherin beta 13
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGB6 protocadherin gamma subfamily B, 6
PGAM2 phosphoglycerate mutase 2 (muscle)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX1 PBX/knotted 1 homeobox 1
PLD1 phospholipase D1, phosphatidylcholine-specific
POU5F1B POU class 5 homeobox 1B
POU6F1 POU class 6 homeobox 1
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTGDR2 prostaglandin D2 receptor 2
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SCRT1 scratch family zinc finger 1
SGSM3 small G protein signaling modulator 3
SH3D21 SH3 domain containing 21
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOCS3 suppressor of cytokine signaling 3
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TBXA2R thromboxane A2 receptor
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TLR1 toll-like receptor 1
TNNT3 troponin T type 3 (skeletal, fast)
TRH thyrotropin-releasing hormone
TRIM29 tripartite motif containing 29
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSPAN2 tetraspanin 2
VAX2 ventral anterior homeobox 2
ZFHX2 zinc finger homeobox 2
ZNF154 zinc finger protein 154
ZNF609 zinc finger protein 609
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACE angiotensin I converting enzyme
ACKR3 atypical chemokine receptor 3
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOC4 apolipoprotein C-IV
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AUH AU RNA binding protein/enoyl-CoA hydratase
AVPI1 arginine vasopressin-induced 1
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BOLA1 bolA family member 1
C17ORF70 chromosome 17 open reading frame 70
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CA5B carbonic anhydrase VB, mitochondrial
CASS4 Cas scaffolding protein family member 4
CCNA1 cyclin A1
CD79A CD79a molecule, immunoglobulin-associated alpha
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN15 claudin 15
CLIC3 chloride intracellular channel 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNN1 calponin 1, basic, smooth muscle
CPZ carboxypeptidase Z
DAGLA diacylglycerol lipase, alpha
DCSTAMP dendrocyte expressed seven transmembrane protein
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DMTN dematin actin binding protein
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DTX2 deltex 2, E3 ubiquitin ligase
ELP6 elongator acetyltransferase complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HESX1 HESX homeobox 1
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
HIST1H2BN histone cluster 1, H2bn
HIST1H3B histone cluster 1, H3b
HMHA1 histocompatibility (minor) HA-1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
IQCG IQ motif containing G
JUNB jun B proto-oncogene
KIAA1107 KIAA1107
KIRREL kin of IRRE like (Drosophila)
LIFR leukemia inhibitory factor receptor alpha
LIG4 ligase IV, DNA, ATP-dependent
LRRC6 leucine rich repeat containing 6
MAPK12 mitogen-activated protein kinase 12
MILR1 mast cell immunoglobulin-like receptor 1
MUC3B mucin 3B, cell surface associated
MXD3 MAX dimerization protein 3
MYO1F myosin IF
NT5M 5',3'-nucleotidase, mitochondrial
OSBP2 oxysterol binding protein 2
OVGP1 oviductal glycoprotein 1, 120kDa
PALMD palmdelphin
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF25 ring finger protein 25
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD2A RWD domain containing 2A
SCN1B sodium channel, voltage gated, type I beta subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNTG1 syntrophin, gamma 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TAGLN3 transgelin 3
TM7SF3 transmembrane 7 superfamily member 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA4B tubulin, alpha 4b
WDR25 WD repeat domain 25
WNT7A wingless-type MMTV integration site family, member 7A
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZNF215 zinc finger protein 215
ZNF253 zinc finger protein 253
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZNF711 zinc finger protein 711