Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the erythromycin-6729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
APC2 | adenomatosis polyposis coli 2 |
ASCL1 | achaete-scute family bHLH transcription factor 1 |
ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
BTN3A1 | butyrophilin, subfamily 3, member A1 |
CCDC28B | coiled-coil domain containing 28B |
CCDC71 | coiled-coil domain containing 71 |
CD82 | CD82 molecule |
CDC14A | cell division cycle 14A |
CDC42 | cell division cycle 42 |
CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
CLDN18 | claudin 18 |
CLSPN | claspin |
CRHR1 | corticotropin releasing hormone receptor 1 |
CST5 | cystatin D |
CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
DLC1 | DLC1 Rho GTPase activating protein |
DNAAF1 | dynein, axonemal, assembly factor 1 |
DTNB | dystrobrevin, beta |
DUSP9 | dual specificity phosphatase 9 |
EFHC2 | EF-hand domain (C-terminal) containing 2 |
EFNB1 | ephrin-B1 |
ELK1 | ELK1, member of ETS oncogene family |
EPS8L1 | EPS8-like 1 |
FBLN1 | fibulin 1 |
GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
GGT1 | gamma-glutamyltransferase 1 |
GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
GPR21 | G protein-coupled receptor 21 |
GRIK5 | glutamate receptor, ionotropic, kainate 5 |
GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
HAP1 | huntingtin-associated protein 1 |
HHLA1 | HERV-H LTR-associating 1 |
HIP1 | huntingtin interacting protein 1 |
HIPK3 | homeodomain interacting protein kinase 3 |
HIST1H3I | histone cluster 1, H3i |
IGFBP7 | insulin-like growth factor binding protein 7 |
IL11 | interleukin 11 |
ITGB6 | integrin, beta 6 |
KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
KCNJ13 | potassium channel, inwardly rectifying subfamily J, member 13 |
KIAA1467 | KIAA1467 |
KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
KRAS | Kirsten rat sarcoma viral oncogene homolog |
KRT38 | keratin 38, type I |
LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
LAPTM5 | lysosomal protein transmembrane 5 |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LYZ | lysozyme |
MEG3 | maternally expressed 3 (non-protein coding) |
MRPS18C | mitochondrial ribosomal protein S18C |
MS4A5 | membrane-spanning 4-domains, subfamily A, member 5 |
MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
NEK9 | NIMA-related kinase 9 |
NNMT | nicotinamide N-methyltransferase |
NRAP | nebulin-related anchoring protein |
NXPH4 | neurexophilin 4 |
OMD | osteomodulin |
PALM | paralemmin |
PASK | PAS domain containing serine/threonine kinase |
PCDHB13 | protocadherin beta 13 |
PCDHGA11 | protocadherin gamma subfamily A, 11 |
PCDHGB6 | protocadherin gamma subfamily B, 6 |
PGAM2 | phosphoglycerate mutase 2 (muscle) |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PKNOX1 | PBX/knotted 1 homeobox 1 |
PLD1 | phospholipase D1, phosphatidylcholine-specific |
POU5F1B | POU class 5 homeobox 1B |
POU6F1 | POU class 6 homeobox 1 |
PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
PTGDR2 | prostaglandin D2 receptor 2 |
RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
RUNDC3A | RUN domain containing 3A |
RUNX1 | runt-related transcription factor 1 |
SCRT1 | scratch family zinc finger 1 |
SGSM3 | small G protein signaling modulator 3 |
SH3D21 | SH3 domain containing 21 |
SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
SOCS3 | suppressor of cytokine signaling 3 |
SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
TBXA2R | thromboxane A2 receptor |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TLR1 | toll-like receptor 1 |
TNNT3 | troponin T type 3 (skeletal, fast) |
TRH | thyrotropin-releasing hormone |
TRIM29 | tripartite motif containing 29 |
TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
TSPAN2 | tetraspanin 2 |
VAX2 | ventral anterior homeobox 2 |
ZFHX2 | zinc finger homeobox 2 |
ZNF154 | zinc finger protein 154 |
ZNF609 | zinc finger protein 609 |
ZNF688 | zinc finger protein 688 |
Symbol | Name |
---|---|
ACAD10 | acyl-CoA dehydrogenase family, member 10 |
ACE | angiotensin I converting enzyme |
ACKR3 | atypical chemokine receptor 3 |
AFAP1 | actin filament associated protein 1 |
AGMAT | agmatine ureohydrolase (agmatinase) |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
APOC4 | apolipoprotein C-IV |
ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
AUH | AU RNA binding protein/enoyl-CoA hydratase |
AVPI1 | arginine vasopressin-induced 1 |
AXIN1 | axin 1 |
B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
BOLA1 | bolA family member 1 |
C17ORF70 | chromosome 17 open reading frame 70 |
C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
C22ORF29 | chromosome 22 open reading frame 29 |
C7ORF43 | chromosome 7 open reading frame 43 |
CA5B | carbonic anhydrase VB, mitochondrial |
CASS4 | Cas scaffolding protein family member 4 |
CCNA1 | cyclin A1 |
CD79A | CD79a molecule, immunoglobulin-associated alpha |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CLDN15 | claudin 15 |
CLIC3 | chloride intracellular channel 3 |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
CNN1 | calponin 1, basic, smooth muscle |
CPZ | carboxypeptidase Z |
DAGLA | diacylglycerol lipase, alpha |
DCSTAMP | dendrocyte expressed seven transmembrane protein |
DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
DMTN | dematin actin binding protein |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DTX2 | deltex 2, E3 ubiquitin ligase |
ELP6 | elongator acetyltransferase complex subunit 6 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
EXD3 | exonuclease 3'-5' domain containing 3 |
FLT4 | fms-related tyrosine kinase 4 |
FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
HESX1 | HESX homeobox 1 |
HIRA | histone cell cycle regulator |
HIST1H2AI | histone cluster 1, H2ai |
HIST1H2AM | histone cluster 1, H2am |
HIST1H2BN | histone cluster 1, H2bn |
HIST1H3B | histone cluster 1, H3b |
HMHA1 | histocompatibility (minor) HA-1 |
HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
HOOK1 | hook microtubule-tethering protein 1 |
HSPA1L | heat shock 70kDa protein 1-like |
HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
IQCG | IQ motif containing G |
JUNB | jun B proto-oncogene |
KIAA1107 | KIAA1107 |
KIRREL | kin of IRRE like (Drosophila) |
LIFR | leukemia inhibitory factor receptor alpha |
LIG4 | ligase IV, DNA, ATP-dependent |
LRRC6 | leucine rich repeat containing 6 |
MAPK12 | mitogen-activated protein kinase 12 |
MILR1 | mast cell immunoglobulin-like receptor 1 |
MUC3B | mucin 3B, cell surface associated |
MXD3 | MAX dimerization protein 3 |
MYO1F | myosin IF |
NT5M | 5',3'-nucleotidase, mitochondrial |
OSBP2 | oxysterol binding protein 2 |
OVGP1 | oviductal glycoprotein 1, 120kDa |
PALMD | palmdelphin |
PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PTK6 | protein tyrosine kinase 6 |
QSER1 | glutamine and serine rich 1 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RNF25 | ring finger protein 25 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RWDD2A | RWD domain containing 2A |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
SNTG1 | syntrophin, gamma 1 |
ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
TAGLN3 | transgelin 3 |
TM7SF3 | transmembrane 7 superfamily member 3 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
TUBA4B | tubulin, alpha 4b |
WDR25 | WD repeat domain 25 |
WNT7A | wingless-type MMTV integration site family, member 7A |
XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
YY2 | YY2 transcription factor |
ZNF215 | zinc finger protein 215 |
ZNF253 | zinc finger protein 253 |
ZNF552 | zinc finger protein 552 |
ZNF668 | zinc finger protein 668 |
ZNF711 | zinc finger protein 711 |