ergocalciferol-6746 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ergocalciferol-6746 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN2 actinin, alpha 2
ADGRB2 adhesion G protein-coupled receptor B2
ADRA2C adrenoceptor alpha 2C
AIF1 allograft inflammatory factor 1
AIM1L absent in melanoma 1-like
ALK anaplastic lymphoma receptor tyrosine kinase
APOC1 apolipoprotein C-I
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARID4B AT rich interactive domain 4B (RBP1-like)
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C10ORF12 chromosome 10 open reading frame 12
C1ORF61 chromosome 1 open reading frame 61
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC181 coiled-coil domain containing 181
CCL23 chemokine (C-C motif) ligand 23
CDC42 cell division cycle 42
CEP68 centrosomal protein 68kDa
CLDN17 claudin 17
CLTB clathrin, light chain B
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DLX2 distal-less homeobox 2
DNASE1L3 deoxyribonuclease I-like 3
EFR3B EFR3 homolog B (S. cerevisiae)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPX eosinophil peroxidase
FABP7 fatty acid binding protein 7, brain
FLOT1 flotillin 1
FMOD fibromodulin
FOXN2 forkhead box N2
FRMD4B FERM domain containing 4B
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GJA8 gap junction protein, alpha 8, 50kDa
GOLGA8A golgin A8 family, member A
GUK1 guanylate kinase 1
HIC2 hypermethylated in cancer 2
HMOX1 heme oxygenase 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGLJ3 immunoglobulin lambda joining 3
IL12A interleukin 12A
ING4 inhibitor of growth family, member 4
IRF5 interferon regulatory factor 5
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB8 integrin, beta 8
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA1467 KIAA1467
KLK12 kallikrein-related peptidase 12
LARGE like-glycosyltransferase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100286895 cell division cycle 27 homolog pseudogene
LPPR4 lipid phosphate phosphatase-related protein type 4
LTBP4 latent transforming growth factor beta binding protein 4
MCTP2 multiple C2 domains, transmembrane 2
MEG3 maternally expressed 3 (non-protein coding)
MPPE1 metallophosphoesterase 1
MRPS18C mitochondrial ribosomal protein S18C
MST1L macrophage stimulating 1-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC7 mucin 7, secreted
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARVA parvin, alpha
PAX3 paired box 3
PCDHB3 protocadherin beta 3
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRB1 proline-rich protein BstNI subfamily 1
PRO2964 uncharacterized protein PRO2964
RHAG Rh-associated glycoprotein
RNF126P1 ring finger protein 126 pseudogene 1
RPL35A ribosomal protein L35a
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SH3D21 SH3 domain containing 21
SIRT4 sirtuin 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SRRM2 serine/arginine repetitive matrix 2
SSX3 synovial sarcoma, X breakpoint 3
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBC1D2 TBC1 domain family, member 2
TCF3 transcription factor 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM121 transmembrane protein 121
TMEM231 transmembrane protein 231
TTLL5 tubulin tyrosine ligase-like family member 5
VAMP5 vesicle-associated membrane protein 5
VN1R1 vomeronasal 1 receptor 1
ZBTB20 zinc finger and BTB domain containing 20
ZNF268 zinc finger protein 268
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD17B abhydrolase domain containing 17B
ABHD8 abhydrolase domain containing 8
ACOX2 acyl-CoA oxidase 2, branched chain
AGO4 argonaute RISC catalytic component 4
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARMCX4 armadillo repeat containing, X-linked 4
ARSB arylsulfatase B
BOLA1 bolA family member 1
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK6 cyclin-dependent kinase 6
CDKL3 cyclin-dependent kinase-like 3
CENPO centromere protein O
CEP131 centrosomal protein 131kDa
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CPNE7 copine VII
CPZ carboxypeptidase Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXORF56 chromosome X open reading frame 56
DMTN dematin actin binding protein
DTX2 deltex 2, E3 ubiquitin ligase
ELSPBP1 epididymal sperm binding protein 1
FAM184A family with sequence similarity 184, member A
FAM188A family with sequence similarity 188, member A
FBXO2 F-box protein 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GLDC glycine dehydrogenase (decarboxylating)
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
H1F0 H1 histone family, member 0
HOOK1 hook microtubule-tethering protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HYAL2 hyaluronoglucosaminidase 2
IL6 interleukin 6
IREB2 iron-responsive element binding protein 2
KIAA0753 KIAA0753
KIAA1462 KIAA1462
KLF11 Kruppel-like factor 11
KRT75 keratin 75, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LIMS2 LIM and senescent cell antigen-like domains 2
LMO7 LIM domain 7
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MANSC1 MANSC domain containing 1
MFSD6 major facilitator superfamily domain containing 6
MILR1 mast cell immunoglobulin-like receptor 1
MTA2 metastasis associated 1 family, member 2
MUC3A mucin 3A, cell surface associated
NOL12 nucleolar protein 12
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PC pyruvate carboxylase
PID1 phosphotyrosine interaction domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RARS arginyl-tRNA synthetase
RHOBTB2 Rho-related BTB domain containing 2
SCAMP5 secretory carrier membrane protein 5
SEC14L2 SEC14-like 2 (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMAD7 SMAD family member 7
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SND1-IT1 SND1 intronic transcript 1
TBC1D22B TBC1 domain family, member 22B
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TGIF1 TGFB-induced factor homeobox 1
THBS3 thrombospondin 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM62 transmembrane protein 62
TMOD3 tropomodulin 3 (ubiquitous)
TPRA1 transmembrane protein, adipocyte asscociated 1
TUBB2B tubulin, beta 2B class IIb
UGT8 UDP glycosyltransferase 8
USP18 ubiquitin specific peptidase 18
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR18 WD repeat domain 18
YOD1 YOD1 deubiquitinase
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF137P zinc finger protein 137, pseudogene
ZNF529 zinc finger protein 529
ZNF747 zinc finger protein 747
ZXDB zinc finger, X-linked, duplicated B