erbb signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0038127)
External Link http://amigo.geneontology.org/amigo/term/GO:0038127
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Genes

199 genes participating in the erbb signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADRBK1 adrenergic, beta, receptor kinase 1
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AREG amphiregulin
ARF4 ADP-ribosylation factor 4
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BTC betacellulin
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMLG calcium modulating ligand
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD19 CD19 molecule
CD28 CD28 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHUK conserved helix-loop-helix ubiquitous kinase
CLTA clathrin, light chain A
CREB1 cAMP responsive element binding protein 1
CSK c-src tyrosine kinase
DGKD diacylglycerol kinase, delta 130kDa
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPN1 epsin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB2IP erbb2 interacting protein
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
FES FES proto-oncogene, tyrosine kinase
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FRS2 fibroblast growth factor receptor substrate 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAREM GRB2 associated, regulator of MAPK1
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HBEGF heparin-binding EGF-like growth factor
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HRAS Harvey rat sarcoma viral oncogene homolog
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KIF16B kinesin family member 16B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLB klotho beta
KRAS Kirsten rat sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MOV10 Mov10 RISC complex RNA helicase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MVP major vault protein
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCK2 NCK adaptor protein 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG4 neuregulin 4
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGR polymeric immunoglobulin receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRR protein tyrosine phosphatase, receptor type, R
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REPS2 RALBP1 associated Eps domain containing 2
RICTOR RPTOR independent companion of MTOR, complex 2
RPS27A ribosomal protein S27a
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SOCS5 suppressor of cytokine signaling 5
SOS1 son of sevenless homolog 1 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TDGF1 teratocarcinoma-derived growth factor 1
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THEM4 thioesterase superfamily member 4
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TNRC6C trinucleotide repeat containing 6C
TRAT1 T cell receptor associated transmembrane adaptor 1
TRIB3 tribbles pseudokinase 3
TSC2 tuberous sclerosis 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
VAV1 vav 1 guanine nucleotide exchange factor
VIL1 villin 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta