Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the erastin-6417 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACOT11 | acyl-CoA thioesterase 11 |
ADCY6 | adenylate cyclase 6 |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
APOL2 | apolipoprotein L, 2 |
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
ARRB2 | arrestin, beta 2 |
ATG2B | autophagy related 2B |
ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BAX | BCL2-associated X protein |
BBS7 | Bardet-Biedl syndrome 7 |
CARD8 | caspase recruitment domain family, member 8 |
CASZ1 | castor zinc finger 1 |
CCNJL | cyclin J-like |
CCNO | cyclin O |
CCSER2 | coiled-coil serine-rich protein 2 |
CD58 | CD58 molecule |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CSNK1E | casein kinase 1, epsilon |
CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
CTSZ | cathepsin Z |
CYLD | cylindromatosis (turban tumor syndrome) |
DDIT4 | DNA-damage-inducible transcript 4 |
DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
DNAL4 | dynein, axonemal, light chain 4 |
EML2 | echinoderm microtubule associated protein like 2 |
EMP1 | epithelial membrane protein 1 |
ETV1 | ets variant 1 |
FAM214B | family with sequence similarity 214, member B |
FANCF | Fanconi anemia, complementation group F |
FGFR1 | fibroblast growth factor receptor 1 |
FLJ11710 | uncharacterized protein FLJ11710 |
FURIN | furin (paired basic amino acid cleaving enzyme) |
GK | glycerol kinase |
GOSR2 | golgi SNAP receptor complex member 2 |
GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMOX1 | heme oxygenase 1 |
IDS | iduronate 2-sulfatase |
IFT122 | intraflagellar transport 122 |
INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
INSIG1 | insulin induced gene 1 |
IQCE | IQ motif containing E |
KIFC1 | kinesin family member C1 |
KLHL20 | kelch-like family member 20 |
KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
LARP6 | La ribonucleoprotein domain family, member 6 |
LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
MAGEH1 | melanoma antigen family H1 |
MAP2K3 | mitogen-activated protein kinase kinase 3 |
MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
MAPK14 | mitogen-activated protein kinase 14 |
MARS | methionyl-tRNA synthetase |
MCM3AP | minichromosome maintenance complex component 3 associated protein |
MFSD6 | major facilitator superfamily domain containing 6 |
NDE1 | nudE neurodevelopment protein 1 |
PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
PDGFA | platelet-derived growth factor alpha polypeptide |
PFDN6 | prefoldin subunit 6 |
PGPEP1 | pyroglutamyl-peptidase I |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PISD | phosphatidylserine decarboxylase |
PKP1 | plakophilin 1 |
POMT2 | protein-O-mannosyltransferase 2 |
PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
PRPH | peripherin |
PTGFR | prostaglandin F receptor (FP) |
PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
RAB17 | RAB17, member RAS oncogene family |
RANGAP1 | Ran GTPase activating protein 1 |
RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
SAPCD1 | suppressor APC domain containing 1 |
SFTPB | surfactant protein B |
SGSM2 | small G protein signaling modulator 2 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SMAD3 | SMAD family member 3 |
SNAP23 | synaptosomal-associated protein, 23kDa |
ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
STC1 | stanniocalcin 1 |
STON1 | stonin 1 |
SYT1 | synaptotagmin I |
TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
THBD | thrombomodulin |
TIMP4 | TIMP metallopeptidase inhibitor 4 |
TMEM259 | transmembrane protein 259 |
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
TRIB3 | tribbles pseudokinase 3 |
TUBGCP2 | tubulin, gamma complex associated protein 2 |
WSB1 | WD repeat and SOCS box containing 1 |
YPEL1 | yippee-like 1 (Drosophila) |
ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
ZBTB20 | zinc finger and BTB domain containing 20 |
ZNF606 | zinc finger protein 606 |
Symbol | Name |
---|---|
A1CF | APOBEC1 complementation factor |
ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
ADAP2 | ArfGAP with dual PH domains 2 |
ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
ANP32A-IT1 | ANP32A intronic transcript 1 |
AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
ARMCX4 | armadillo repeat containing, X-linked 4 |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
C3AR1 | complement component 3a receptor 1 |
C4ORF29 | chromosome 4 open reading frame 29 |
C5ORF42 | chromosome 5 open reading frame 42 |
CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
CENPQ | centromere protein Q |
CHAT | choline O-acetyltransferase |
CRY2 | cryptochrome circadian clock 2 |
DDN | dendrin |
EGF | epidermal growth factor |
FAM50B | family with sequence similarity 50, member B |
FRMD1 | FERM domain containing 1 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
GBP2 | guanylate binding protein 2, interferon-inducible |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GINS3 | GINS complex subunit 3 (Psf3 homolog) |
GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
GRTP1 | growth hormone regulated TBC protein 1 |
HIST1H2AE | histone cluster 1, H2ae |
HIST1H2AJ | histone cluster 1, H2aj |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
HLA-DMB | major histocompatibility complex, class II, DM beta |
HOOK1 | hook microtubule-tethering protein 1 |
HOXA6 | homeobox A6 |
HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
HSF2BP | heat shock transcription factor 2 binding protein |
HYAL3 | hyaluronoglucosaminidase 3 |
IL20RA | interleukin 20 receptor, alpha |
INHBB | inhibin, beta B |
KIAA1456 | KIAA1456 |
KLC2 | kinesin light chain 2 |
KLHL36 | kelch-like family member 36 |
LOC100127972 | uncharacterized LOC100127972 |
LOC100286895 | cell division cycle 27 homolog pseudogene |
MMP10 | matrix metallopeptidase 10 |
MMP2 | matrix metallopeptidase 2 |
MON1B | MON1 secretory trafficking family member B |
NECAB3 | N-terminal EF-hand calcium binding protein 3 |
NELL2 | NEL-like 2 (chicken) |
NOD1 | nucleotide-binding oligomerization domain containing 1 |
NPFFR1 | neuropeptide FF receptor 1 |
NRTN | neurturin |
ODF1 | outer dense fiber of sperm tails 1 |
OSBP2 | oxysterol binding protein 2 |
PADI1 | peptidyl arginine deiminase, type I |
PER3 | period circadian clock 3 |
PLXNA3 | plexin A3 |
PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
POLH | polymerase (DNA directed), eta |
PRAMEF11 | PRAME family member 11 |
PRMT7 | protein arginine methyltransferase 7 |
RAB3A | RAB3A, member RAS oncogene family |
RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
RETN | resistin |
RHOBTB2 | Rho-related BTB domain containing 2 |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SARS2 | seryl-tRNA synthetase 2, mitochondrial |
SAYSD1 | SAYSVFN motif domain containing 1 |
SETD6 | SET domain containing 6 |
SIRT6 | sirtuin 6 |
SIX3 | SIX homeobox 3 |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SLITRK5 | SLIT and NTRK-like family, member 5 |
SMCP | sperm mitochondria-associated cysteine-rich protein |
SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
SOX12 | SRY (sex determining region Y)-box 12 |
STAG3 | stromal antigen 3 |
SULT4A1 | sulfotransferase family 4A, member 1 |
TAOK1 | TAO kinase 1 |
TBXAS1 | thromboxane A synthase 1 (platelet) |
TEAD3 | TEA domain family member 3 |
TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
TMEM121 | transmembrane protein 121 |
TMEM209 | transmembrane protein 209 |
TMEM212 | transmembrane protein 212 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TRAF2 | TNF receptor-associated factor 2 |
TRAPPC13 | trafficking protein particle complex 13 |
TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
TUBA4B | tubulin, alpha 4b |
TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
VASP | vasodilator-stimulated phosphoprotein |
VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
WDR18 | WD repeat domain 18 |
WNT7A | wingless-type MMTV integration site family, member 7A |
XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
ZNF107 | zinc finger protein 107 |
ZNF155 | zinc finger protein 155 |
ZNF408 | zinc finger protein 408 |
ZNF862 | zinc finger protein 862 |