equilin-4659 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the equilin-4659 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM20 ADAM metallopeptidase domain 20
ADGRB2 adhesion G protein-coupled receptor B2
ADGRE2 adhesion G protein-coupled receptor E2
AKAP5 A kinase (PRKA) anchor protein 5
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APOB apolipoprotein B
ATXN7L1 ataxin 7-like 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C2CD2L C2CD2-like
C6ORF10 chromosome 6 open reading frame 10
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAT choline O-acetyltransferase
CHI3L2 chitinase 3-like 2
CIZ1 CDKN1A interacting zinc finger protein 1
CORT cortistatin
CPB1 carboxypeptidase B1 (tissue)
CRMP1 collapsin response mediator protein 1
CRYGD crystallin, gamma D
DCTN1 dynactin 1
E2F4 E2F transcription factor 4, p107/p130-binding
ELOVL5 ELOVL fatty acid elongase 5
EMID1 EMI domain containing 1
ENG endoglin
ERBB4 erb-b2 receptor tyrosine kinase 4
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV6 ets variant 6
EXO5 exonuclease 5
EXOSC1 exosome component 1
FAM63B family with sequence similarity 63, member B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FMOD fibromodulin
FOXO1 forkhead box O1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAL galanin/GMAP prepropeptide
GLI2 GLI family zinc finger 2
GNRHR gonadotropin-releasing hormone receptor
GPR75 G protein-coupled receptor 75
GRM8 glutamate receptor, metabotropic 8
HCRTR2 hypocretin (orexin) receptor 2
HGD homogentisate 1,2-dioxygenase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HR hair growth associated
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL16 interleukin 16
ING2 inhibitor of growth family, member 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLF6 Kruppel-like factor 6
KRT17 keratin 17, type I
LIPE lipase, hormone-sensitive
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRTM2 leucine rich repeat transmembrane neuronal 2
MCPH1 microcephalin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MPPE1 metallophosphoesterase 1
MTAP methylthioadenosine phosphorylase
MTMR1 myotubularin related protein 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MVD mevalonate (diphospho) decarboxylase
NCR2 natural cytotoxicity triggering receptor 2
NEU3 sialidase 3 (membrane sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPVF neuropeptide VF precursor
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAX9 paired box 9
PCDHB3 protocadherin beta 3
PCDHGB6 protocadherin gamma subfamily B, 6
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RBM12B RNA binding motif protein 12B
RCVRN recoverin
RPL10L ribosomal protein L10-like
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RS1 retinoschisin 1
SAA3P serum amyloid A3 pseudogene
SCN11A sodium channel, voltage gated, type XI alpha subunit
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC22A14 solute carrier family 22, member 14
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPON1 spondin 1, extracellular matrix protein
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRPK3 SRSF protein kinase 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SULF1 sulfatase 1
SYMPK symplekin
SYN3 synapsin III
TTC22 tetratricopeptide repeat domain 22
ZFHX2 zinc finger homeobox 2
ZNF749 zinc finger protein 749

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACADSB acyl-CoA dehydrogenase, short/branched chain
AGO4 argonaute RISC catalytic component 4
AMT aminomethyltransferase
AOC2 amine oxidase, copper containing 2 (retina-specific)
ATAD5 ATPase family, AAA domain containing 5
AURKC aurora kinase C
AXIN1 axin 1
C14ORF105 chromosome 14 open reading frame 105
C1RL complement component 1, r subcomponent-like
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CAMKMT calmodulin-lysine N-methyltransferase
CCP110 centriolar coiled coil protein 110kDa
CD79A CD79a molecule, immunoglobulin-associated alpha
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CEP97 centrosomal protein 97kDa
CHMP6 charged multivesicular body protein 6
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREB5 cAMP responsive element binding protein 5
DEPTOR DEP domain containing MTOR-interacting protein
DTX2 deltex 2, E3 ubiquitin ligase
ELOVL4 ELOVL fatty acid elongase 4
EML4 echinoderm microtubule associated protein like 4
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
FLJ21369 uncharacterized protein FLJ21369
FUZ fuzzy planar cell polarity protein
GAS8 growth arrest-specific 8
GEMIN8 gem (nuclear organelle) associated protein 8
GPR3 G protein-coupled receptor 3
GRTP1 growth hormone regulated TBC protein 1
HLX H2.0-like homeobox
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
IL24 interleukin 24
IL32 interleukin 32
INADL InaD-like (Drosophila)
IRAK4 interleukin-1 receptor-associated kinase 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIAA1462 KIAA1462
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL25 kelch-like family member 25
KRT4 keratin 4, type II
LIME1 Lck interacting transmembrane adaptor 1
LMCD1 LIM and cysteine-rich domains 1
LMO7 LIM domain 7
MCC mutated in colorectal cancers
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL52 mitochondrial ribosomal protein L52
MX1 MX dynamin-like GTPase 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NOL10 nucleolar protein 10
NRTN neurturin
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCOLCE procollagen C-endopeptidase enhancer
PID1 phosphotyrosine interaction domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPT2 palmitoyl-protein thioesterase 2
PRB3 proline-rich protein BstNI subfamily 3
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RUNDC3B RUN domain containing 3B
RUNX1-IT1 RUNX1 intronic transcript 1
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SH2D4A SH2 domain containing 4A
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC22A18 solute carrier family 22, member 18
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SP1 Sp1 transcription factor
SPEG SPEG complex locus
SPRYD7 SPRY domain containing 7
STAC SH3 and cysteine rich domain
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SYNGR3 synaptogyrin 3
SYT17 synaptotagmin XVII
TCTN2 tectonic family member 2
TMEM8B transmembrane protein 8B
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUBA4B tubulin, alpha 4b
UBTD1 ubiquitin domain containing 1
ZFHX3 zinc finger homeobox 3
ZNF219 zinc finger protein 219
ZNF276 zinc finger protein 276
ZNF778 zinc finger protein 778