equilin-3377 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the equilin-3377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD2 abhydrolase domain containing 2
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM12 ADAM metallopeptidase domain 12
ADGRL1 adhesion G protein-coupled receptor L1
ADORA1 adenosine A1 receptor
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AREG amphiregulin
ARHGAP26 Rho GTPase activating protein 26
ARTN artemin
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP6 bone morphogenetic protein 6
C3AR1 complement component 3a receptor 1
CA1 carbonic anhydrase I
CAPZB capping protein (actin filament) muscle Z-line, beta
CD47 CD47 molecule
CD8A CD8a molecule
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLTA clathrin, light chain A
CNTN1 contactin 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DAPK3 death-associated protein kinase 3
DIO2 deiodinase, iodothyronine, type II
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDN1 endothelin 1
EGR1 early growth response 1
EGR3 early growth response 3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPHB6 EPH receptor B6
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC2 excision repair cross-complementation group 2
FAM188A family with sequence similarity 188, member A
FAM76A family with sequence similarity 76, member A
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FGF18 fibroblast growth factor 18
FKBP10 FK506 binding protein 10, 65 kDa
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GGT1 gamma-glutamyltransferase 1
GLP1R glucagon-like peptide 1 receptor
GPR176 G protein-coupled receptor 176
HOPX HOP homeobox
IRS2 insulin receptor substrate 2
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF8 Kruppel-like factor 8
KLHL25 kelch-like family member 25
KLK13 kallikrein-related peptidase 13
KRT15 keratin 15, type I
KRT8 keratin 8, type II
LDLR low density lipoprotein receptor
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MOGAT2 monoacylglycerol O-acyltransferase 2
MST1 macrophage stimulating 1
MXD1 MAX dimerization protein 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NMRK1 nicotinamide riboside kinase 1
NPM3 nucleophosmin/nucleoplasmin 3
NPR2 natriuretic peptide receptor 2
NPTXR neuronal pentraxin receptor
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRL neural retina leucine zipper
PADI3 peptidyl arginine deiminase, type III
PBX2 pre-B-cell leukemia homeobox 2
PDE9A phosphodiesterase 9A
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POMT2 protein-O-mannosyltransferase 2
PRDX2 peroxiredoxin 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REEP2 receptor accessory protein 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REPS1 RALBP1 associated Eps domain containing 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERHL2 serine hydrolase-like 2
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SH3GL3 SH3-domain GRB2-like 3
SLC35E2 solute carrier family 35, member E2
SMR3A submaxillary gland androgen regulated protein 3A
SPTBN1 spectrin, beta, non-erythrocytic 1
STS steroid sulfatase (microsomal), isozyme S
TAC3 tachykinin 3
TBX5 T-box 5
TGM2 transglutaminase 2
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TSPAN2 tetraspanin 2
VGF VGF nerve growth factor inducible
VNN2 vanin 2
ZNF117 zinc finger protein 117

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX15 arachidonate 15-lipoxygenase
APOLD1 apolipoprotein L domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C10ORF95 chromosome 10 open reading frame 95
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC132 coiled-coil domain containing 132
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNM3 dynamin 3
DYM dymeclin
EFNA1 ephrin-A1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPPK1 epiplakin 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM131A family with sequence similarity 131, member A
FBXW12 F-box and WD repeat domain containing 12
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
FSCN3 fascin actin-bundling protein 3, testicular
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HP1BP3 heterochromatin protein 1, binding protein 3
HYAL3 hyaluronoglucosaminidase 3
IL12RB1 interleukin 12 receptor, beta 1
IPP intracisternal A particle-promoted polypeptide
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF13A kinesin family member 13A
KRT83 keratin 83, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LRRC37A3 leucine rich repeat containing 37, member A3
LY6D lymphocyte antigen 6 complex, locus D
MBTD1 mbt domain containing 1
MFAP2 microfibrillar-associated protein 2
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PALM paralemmin
PHF14 PHD finger protein 14
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMEL premelanosome protein
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAMEF11 PRAME family member 11
PRR15L proline rich 15-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSCA prostate stem cell antigen
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
S100A9 S100 calcium binding protein A9
SCAI suppressor of cancer cell invasion
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPEG SPEG complex locus
SREK1IP1 SREK1-interacting protein 1
SSTR4 somatostatin receptor 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TBKBP1 TBK1 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCP10 t-complex 10
TEP1 telomerase-associated protein 1
TGFBR3 transforming growth factor, beta receptor III
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
UPK2 uroplakin 2
VASH2 vasohibin 2
VEZT vezatin, adherens junctions transmembrane protein
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF136 zinc finger protein 136
ZNF160 zinc finger protein 160
ZNF423 zinc finger protein 423
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721