epsilon dna polymerase complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair. (Gene Ontology, GO_0008622)
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5 proteins localized to the epsilon dna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CHRAC1 chromatin accessibility complex 1 0.663342
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.663342
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.663342
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.663342
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 0.663342