epivincamine-6838 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the epivincamine-6838 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADAM22 ADAM metallopeptidase domain 22
ADCK2 aarF domain containing kinase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMPD1 adenosine monophosphate deaminase 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP8A bone morphogenetic protein 8a
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALML5 calmodulin-like 5
CCDC40 coiled-coil domain containing 40
CDC14A cell division cycle 14A
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK13 cyclin-dependent kinase 13
CDK3 cyclin-dependent kinase 3
CDRT1 CMT1A duplicated region transcript 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFAP69 cilia and flagella associated protein 69
CMKLR1 chemerin chemokine-like receptor 1
CST4 cystatin S
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNASE1L3 deoxyribonuclease I-like 3
FAM65B family with sequence similarity 65, member B
FBN1 fibrillin 1
FCMR Fc fragment of IgM receptor
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXYD5 FXYD domain containing ion transport regulator 5
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GLRA3 glycine receptor, alpha 3
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRM1 glutamate receptor, metabotropic 1
GRM6 glutamate receptor, metabotropic 6
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HCG4 HLA complex group 4 (non-protein coding)
HNMT histamine N-methyltransferase
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IGSF6 immunoglobulin superfamily, member 6
IL9R interleukin 9 receptor
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAZN kazrin, periplakin interacting protein
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC100131532 uncharacterized LOC100131532
LTC4S leukotriene C4 synthase
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MOBP myelin-associated oligodendrocyte basic protein
MRPS18C mitochondrial ribosomal protein S18C
MYH11 myosin, heavy chain 11, smooth muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOZ3 myozenin 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOP16 NOP16 nucleolar protein
NPR3 natriuretic peptide receptor 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
OXCT2 3-oxoacid CoA transferase 2
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POU6F2 POU class 6 homeobox 2
PQBP1 polyglutamine binding protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL7 ribosomal protein L7
RUFY3 RUN and FYVE domain containing 3
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SDS serine dehydratase
SLAMF8 SLAM family member 8
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC39A9 solute carrier family 39, member 9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLIT2 slit homolog 2 (Drosophila)
SNTA1 syntrophin, alpha 1
SPAG8 sperm associated antigen 8
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAB1 stabilin 1
SYNJ1 synaptojanin 1
TBXA2R thromboxane A2 receptor
TEF thyrotrophic embryonic factor
TFEB transcription factor EB
TIMP3 TIMP metallopeptidase inhibitor 3
TOR4A torsin family 4, member A
ULK2 unc-51 like autophagy activating kinase 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VIPR2 vasoactive intestinal peptide receptor 2
VNN2 vanin 2
VPS9D1 VPS9 domain containing 1
XCR1 chemokine (C motif) receptor 1
XYLB xylulokinase homolog (H. influenzae)
ZNF862 zinc finger protein 862
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABHD3 abhydrolase domain containing 3
ALPK1 alpha-kinase 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARPIN actin-related protein 2/3 complex inhibitor
ATAD5 ATPase family, AAA domain containing 5
BCAS1 breast carcinoma amplified sequence 1
BEX4 brain expressed, X-linked 4
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
CARD8 caspase recruitment domain family, member 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC15 coiled-coil domain containing 15
CCP110 centriolar coiled coil protein 110kDa
CENPQ centromere protein Q
CLSPN claspin
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4A DENN/MADD domain containing 4A
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
FOXJ2 forkhead box J2
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPR19 G protein-coupled receptor 19
GSTTP1 glutathione S-transferase theta pseudogene 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HIST1H4D histone cluster 1, H4d
IDI2-AS1 IDI2 antisense RNA 1
IL17RA interleukin 17 receptor A
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD1C jumonji domain containing 1C
KCTD20 potassium channel tetramerization domain containing 20
KLHL25 kelch-like family member 25
KPTN kaptin (actin binding protein)
KREMEN2 kringle containing transmembrane protein 2
LPXN leupaxin
MFAP2 microfibrillar-associated protein 2
MTG1 mitochondrial ribosome-associated GTPase 1
MVP major vault protein
NPIPB3 nuclear pore complex interacting protein family, member B3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARG poly (ADP-ribose) glycohydrolase
PCSK7 proprotein convertase subtilisin/kexin type 7
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PPT2 palmitoyl-protein thioesterase 2
PRPH peripherin
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL13P5 ribosomal protein L13 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SFT2D2 SFT2 domain containing 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOWAHC sosondowah ankyrin repeat domain family member C
SP140L SP140 nuclear body protein-like
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYBU syntabulin (syntaxin-interacting)
TBX19 T-box 19
TESK2 testis-specific kinase 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TPST1 tyrosylprotein sulfotransferase 1
TRAIP TRAF interacting protein
TRAPPC2 trafficking protein particle complex 2
TSSC4 tumor suppressing subtransferable candidate 4
TTBK2 tau tubulin kinase 2
TTC23 tetratricopeptide repeat domain 23
USB1 U6 snRNA biogenesis 1
ZNF211 zinc finger protein 211
ZNF276 zinc finger protein 276
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF8 zinc finger protein 8