epithelial to mesenchymal transition Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. (Gene Ontology, GO_0001837)
External Link http://amigo.geneontology.org/amigo/term/GO:0001837
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Genes

50 genes participating in the epithelial to mesenchymal transition biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AMELX amelogenin, X-linked
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL7 cullin 7
EFNA1 ephrin-A1
EOMES eomesodermin
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM101B family with sequence similarity 101, member B
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR2 fibroblast growth factor receptor 2
FLNA filamin A, alpha
FOXF2 forkhead box F2
GSK3B glycogen synthase kinase 3 beta
HAS2 hyaluronan synthase 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
LEF1 lymphoid enhancer-binding factor 1
LIMS1 LIM and senescent cell antigen-like domains 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LRP6 low density lipoprotein receptor-related protein 6
MSX1 msh homeobox 1
MSX2 msh homeobox 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOG noggin
NOTCH1 notch 1
OLFM1 olfactomedin 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RTN4 reticulon 4
S100A4 S100 calcium binding protein A4
SMAD4 SMAD family member 4
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR3 transforming growth factor, beta receptor III
TRIM28 tripartite motif containing 28
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A