epithelial stem cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Epithelial stem cells in the lining of the digestive tract occur in deep crypts and give rise to several cell types: absorptive cells, goblet cells, paneth cells, and enteroendocrine cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0005096)
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Genes

166 proteins co-occuring with the tissue epithelial stem cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
KRT15 keratin 15, type I 2.12512
KRT3 keratin 3, type II 1.8189
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.76676
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.70047
KRT14 keratin 14, type I 1.50953
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 1.37636
CD200 CD200 molecule 1.34451
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 1.30883
PROM1 prominin 1 1.09916
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.06559
PAX6 paired box 6 1.01943
SOX2 SRY (sex determining region Y)-box 2 0.985859
KRT1 keratin 1, type II 0.984556
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.974583
DCLK1 doublecortin-like kinase 1 0.96809
FGF10 fibroblast growth factor 10 0.954271
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.944796
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.910093
KRT6A keratin 6A, type II 0.888829
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.879512
ITGA6 integrin, alpha 6 0.872327
NGFR nerve growth factor receptor 0.871483
NES nestin 0.856732
NOTCH1 notch 1 0.85505
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.844965
NID2 nidogen 2 (osteonidogen) 0.832804
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 0.822339
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.813979
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 0.803961
TP53 tumor protein p53 0.797291
FOXN1 forkhead box N1 0.793959
SHH sonic hedgehog 0.788964
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.783557
LEF1 lymphoid enhancer-binding factor 1 0.761155
CD34 CD34 molecule 0.758259
NANOG Nanog homeobox 0.750818
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.74009
S100A3 S100 calcium binding protein A3 0.735559
MATN4 matrilin 4 0.731031
MXD1 MAX dimerization protein 1 0.727741
MATN2 matrilin 2 0.714189
S100A6 S100 calcium binding protein A6 0.713369
CD24 CD24 molecule 0.705583
C3ORF18 chromosome 3 open reading frame 18 0.703536
ARID5B AT rich interactive domain 5B (MRF1-like) 0.684327
ITM2A integral membrane protein 2A 0.672506
KRT38 keratin 38, type I 0.667622
KRT8 keratin 8, type II 0.667215
PITX2 paired-like homeodomain 2 0.663555
LHX2 LIM homeobox 2 0.659085
KRT5 keratin 5, type II 0.659085
LOR loricrin 0.654618
FLG filaggrin 0.646505
ESRP1 epithelial splicing regulatory protein 1 0.62385
LPP LIM domain containing preferred translocation partner in lipoma 0.591641
RREB1 ras responsive element binding protein 1 0.569222
KRT19 keratin 19, type I 0.566428
GJA1 gap junction protein, alpha 1, 43kDa 0.556865
SOSTDC1 sclerostin domain containing 1 0.546929
NCOR1 nuclear receptor corepressor 1 0.533856
SCRIB scribbled planar cell polarity protein 0.529508
SOX13 SRY (sex determining region Y)-box 13 0.52635
FERMT1 fermitin family member 1 0.525955
S100A4 S100 calcium binding protein A4 0.521617
ATOH1 atonal homolog 1 (Drosophila) 0.519253
BNC1 basonuclin 1 0.514924
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.513743
FGF7 fibroblast growth factor 7 0.509027
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.505887
BMPER BMP binding endothelial regulator 0.498048
NTN4 netrin 4 0.497266
GLI1 GLI family zinc finger 1 0.495701
FZD7 frizzled class receptor 7 0.491791
PCNA proliferating cell nuclear antigen 0.489447
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.485935
GATA6 GATA binding protein 6 0.481648
SOX9 SRY (sex determining region Y)-box 9 0.479312
DSTN destrin (actin depolymerizing factor) 0.478145
CDKN2A cyclin-dependent kinase inhibitor 2A 0.477367
AMELY amelogenin, Y-linked 0.476201
TRAF4 TNF receptor-associated factor 4 0.47348
FGF1 fibroblast growth factor 1 (acidic) 0.47348
AXIN2 axin 2 0.469599
FGF9 fibroblast growth factor 9 0.468824
FOXA1 forkhead box A1 0.467273
AMELX amelogenin, X-linked 0.466885
PLXND1 plexin D1 0.4634
SPRY4 sprouty homolog 4 (Drosophila) 0.463013
SPON1 spondin 1, extracellular matrix protein 0.461852
TP63 tumor protein p63 0.457987
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.45567
JAG1 jagged 1 0.452969
KRT10 keratin 10, type I 0.452584
FST follistatin 0.444499
BMP4 bone morphogenetic protein 4 0.431077
AXIN1 axin 1 0.427636
CD44 CD44 molecule (Indian blood group) 0.426109
THY1 Thy-1 cell surface antigen 0.423818
COL4A1 collagen, type IV, alpha 1 0.420004
TFRC transferrin receptor 0.411251
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.405555
DUSP5 dual specificity phosphatase 5 0.405176
HBA1 hemoglobin, alpha 1 0.401386
HBA2 hemoglobin, alpha 2 0.388912
MMP11 matrix metallopeptidase 11 0.387781
MIR203A microRNA 203a 0.38552
WNT5B wingless-type MMTV integration site family, member 5B 0.382884
HNF4A hepatocyte nuclear factor 4, alpha 0.379499
FICD FIC domain containing 0.377245
TBX18 T-box 18 0.374993
EFNB3 ephrin-B3 0.372743
CHGA chromogranin A 0.371994
SFRP5 secreted frizzled-related protein 5 0.369747
KRT12 keratin 12, type I 0.364139
DEFA5 defensin, alpha 5, Paneth cell-specific 0.362273
SOX10 SRY (sex determining region Y)-box 10 0.359664
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.357802
DLK1 delta-like 1 homolog (Drosophila) 0.353712
SMAD4 SMAD family member 4 0.350743
ACTG2 actin, gamma 2, smooth muscle, enteric 0.350372
WNT1 wingless-type MMTV integration site family, member 1 0.350001
HDGF hepatoma-derived growth factor 0.335233
CTBS chitobiase, di-N-acetyl- 0.333028
KRT75 keratin 75, type II 0.333028
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.333028
TP73 tumor protein p73 0.324605
ZEB1 zinc finger E-box binding homeobox 1 0.324239
WISP1 WNT1 inducible signaling pathway protein 1 0.315135
SPRY2 sprouty homolog 2 (Drosophila) 0.312595
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.310783
DICER1 dicer 1, ribonuclease type III 0.310421
SPDEF SAM pointed domain containing ETS transcription factor 0.305722
WNT3 wingless-type MMTV integration site family, member 3 0.30464
TGFB1 transforming growth factor, beta 1 0.301758
FGFR3 fibroblast growth factor receptor 3 0.293866
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.293151
UPK3A uroplakin 3A 0.284962
DCT dopachrome tautomerase 0.2779
SOX4 SRY (sex determining region Y)-box 4 0.277549
KRT17 keratin 17, type I 0.267446
EMP1 epithelial membrane protein 1 0.25858
SMAD2 SMAD family member 2 0.257237
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.257237
PDCD1LG2 programmed cell death 1 ligand 2 0.255567
NOG noggin 0.25457
DCC DCC netrin 1 receptor 0.253908
CRYGS crystallin, gamma S 0.250953
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.247399
E2F3 E2F transcription factor 3 0.246442
SP1 Sp1 transcription factor 0.246442
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.245175
MEIS1 Meis homeobox 1 0.24486
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.242983
KRT13 keratin 13, type I 0.234302
SOX1 SRY (sex determining region Y)-box 1 0.233162
PTCH1 patched 1 0.229839
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.226667
IFITM1 interferon induced transmembrane protein 1 0.224398
CD9 CD9 molecule 0.221755
CSN1S1 casein alpha s1 0.220152
TRIAP1 TP53 regulated inhibitor of apoptosis 1 0.21883
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.218398
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.214954
KLF4 Kruppel-like factor 4 (gut) 0.21365
CNTF ciliary neurotrophic factor 0.213471
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.212413