epirizole-7292 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the epirizole-7292 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY6 adenylate cyclase 6
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANGPTL2 angiopoietin-like 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP35 Rho GTPase activating protein 35
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC9 armadillo repeat containing 9
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C22ORF29 chromosome 22 open reading frame 29
C4ORF19 chromosome 4 open reading frame 19
CDC25C cell division cycle 25C
CDK3 cyclin-dependent kinase 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP162 centrosomal protein 162kDa
CLCN4 chloride channel, voltage-sensitive 4
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNTNAP2 contactin associated protein-like 2
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DAPK3 death-associated protein kinase 3
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
EFNA3 ephrin-A3
ELOVL5 ELOVL fatty acid elongase 5
FOXG1 forkhead box G1
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FRMD8 FERM domain containing 8
GATA2 GATA binding protein 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAUS5 HAUS augmin-like complex, subunit 5
HIST1H1D histone cluster 1, H1d
HIST1H2BO histone cluster 1, H2bo
IFNA14 interferon, alpha 14
IQCG IQ motif containing G
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB5 integrin, beta 5
LIPG lipase, endothelial
MAPK7 mitogen-activated protein kinase 7
MARS methionyl-tRNA synthetase
MIIP migration and invasion inhibitory protein
MTCP1 mature T-cell proliferation 1
NDE1 nudE neurodevelopment protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAX2 paired box 2
PBX2 pre-B-cell leukemia homeobox 2
PCDH7 protocadherin 7
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PLD3 phospholipase D family, member 3
PLXNB3 plexin B3
PLXND1 plexin D1
PMFBP1 polyamine modulated factor 1 binding protein 1
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
PRLR prolactin receptor
RAD52 RAD52 homolog (S. cerevisiae)
SAP30 Sin3A-associated protein, 30kDa
SENP6 SUMO1/sentrin specific peptidase 6
SH3BP2 SH3-domain binding protein 2
SIVA1 SIVA1, apoptosis-inducing factor
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SOBP sine oculis binding protein homolog (Drosophila)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TGFBI transforming growth factor, beta-induced, 68kDa
TIAM1 T-cell lymphoma invasion and metastasis 1
TK2 thymidine kinase 2, mitochondrial
TLN2 talin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM63A transmembrane protein 63A
TNK1 tyrosine kinase, non-receptor, 1
TNS1 tensin 1
TPM1 tropomyosin 1 (alpha)
TRIM14 tripartite motif containing 14
TRIM25 tripartite motif containing 25
TROVE2 TROVE domain family, member 2
TUSC3 tumor suppressor candidate 3
TXLNG taxilin gamma
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)
ZC3H7B zinc finger CCCH-type containing 7B
ZER1 zyg-11 related, cell cycle regulator
ZFP30 ZFP30 zinc finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZHX3 zinc fingers and homeoboxes 3
ZNF639 zinc finger protein 639
ZNF770 zinc finger protein 770
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACVR2B activin A receptor, type IIB
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD40 ankyrin repeat domain 40
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGAP5 Rho GTPase activating protein 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BBS1 Bardet-Biedl syndrome 1
BIN3 bridging integrator 3
BOLA1 bolA family member 1
C1ORF159 chromosome 1 open reading frame 159
CAPN5 calpain 5
CCDC88C coiled-coil domain containing 88C
CDKN2AIP CDKN2A interacting protein
CFAP69 cilia and flagella associated protein 69
CHKB choline kinase beta
CLASP1 cytoplasmic linker associated protein 1
CLEC16A C-type lectin domain family 16, member A
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COMMD10 COMM domain containing 10
CORO2A coronin, actin binding protein, 2A
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DLK1 delta-like 1 homolog (Drosophila)
DNM1 dynamin 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EIF5A2 eukaryotic translation initiation factor 5A2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM57A family with sequence similarity 57, member A
FANCF Fanconi anemia, complementation group F
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXJ2 forkhead box J2
FZD3 frizzled class receptor 3
GPATCH2L G patch domain containing 2-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
HAUS6 HAUS augmin-like complex, subunit 6
HDAC5 histone deacetylase 5
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
HIST1H3G histone cluster 1, H3g
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMOX1 heme oxygenase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
IFI6 interferon, alpha-inducible protein 6
INF2 inverted formin, FH2 and WH2 domain containing
IREB2 iron-responsive element binding protein 2
KDM4D lysine (K)-specific demethylase 4D
KIAA0894 KIAA0894 protein
KIAA1462 KIAA1462
KIRREL kin of IRRE like (Drosophila)
KLC2 kinesin light chain 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MANBA mannosidase, beta A, lysosomal
MCMBP minichromosome maintenance complex binding protein
MFGE8 milk fat globule-EGF factor 8 protein
MGC12488
MN1 meningioma (disrupted in balanced translocation) 1
MNS1 meiosis-specific nuclear structural 1
MOGS mannosyl-oligosaccharide glucosidase
MRPL44 mitochondrial ribosomal protein L44
MXRA8 matrix-remodelling associated 8
NABP2 nucleic acid binding protein 2
OSMR oncostatin M receptor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCOLCE procollagen C-endopeptidase enhancer
PEG3 paternally expressed 3
PHKG2 phosphorylase kinase, gamma 2 (testis)
RBL1 retinoblastoma-like 1
RNF170 ring finger protein 170
S100A14 S100 calcium binding protein A14
SFT2D2 SFT2 domain containing 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAR steroidogenic acute regulatory protein
TBC1D16 TBC1 domain family, member 16
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESK1 testis-specific kinase 1
TMEM104 transmembrane protein 104
TMEM132A transmembrane protein 132A
TMEM57 transmembrane protein 57
TMOD3 tropomodulin 3 (ubiquitous)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOR4A torsin family 4, member A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUBA3C tubulin, alpha 3c
ZBTB25 zinc finger and BTB domain containing 25
ZC3H12A zinc finger CCCH-type containing 12A
ZNF350 zinc finger protein 350
ZNF574 zinc finger protein 574
ZNHIT2 zinc finger, HIT-type containing 2