epidermis stratum spinosum hyperplasia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description overdevelopment or increased size, usually due an increased number of cells, of the layer of polyhedral cells in the epidermis; shrinkage and adhesion of these cells gives a spiny or prickly appearance (Mammalian Phenotype Ontology, MP_0009611)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009611
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Genes

35 gene mutations causing the epidermis stratum spinosum hyperplasia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABHD5 abhydrolase domain containing 5
AHR aryl hydrocarbon receptor
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CDSN corneodesmosin
CTSV cathepsin V
DSG4 desmoglein 4
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
FGFR2 fibroblast growth factor receptor 2
FLG filaggrin
HR hair growth associated
IL22 interleukin 22
IL36RN interleukin 36 receptor antagonist
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT9 keratin 9, type I
LAMC2 laminin, gamma 2
LBR lamin B receptor
MTA2 metastasis associated 1 family, member 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
PKP3 plakophilin 3
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SHARPIN SHANK-associated RH domain interactor
SPINK5 serine peptidase inhibitor, Kazal type 5
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TMEM79 transmembrane protein 79
TP63 tumor protein p63
TTC7A tetratricopeptide repeat domain 7A
UROS uroporphyrinogen III synthase
XPA xeroderma pigmentosum, complementation group A