epiandrosterone-2444 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the epiandrosterone-2444 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKMY1 ankyrin repeat and MYND domain containing 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AR androgen receptor
ATP13A2 ATPase type 13A2
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AURKA aurora kinase A
BAIAP2 BAI1-associated protein 2
BCL2L1 BCL2-like 1
BGN biglycan
C19ORF73 chromosome 19 open reading frame 73
CALD1 caldesmon 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD84 CD84 molecule
CDC14B cell division cycle 14B
CFP complement factor properdin
CHN2 chimerin 2
CLIC5 chloride intracellular channel 5
ELL elongation factor RNA polymerase II
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPN1 epsin 1
EPS8L1 EPS8-like 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERC2-IT1 ERC2 intronic transcript 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ETAA1 Ewing tumor-associated antigen 1
FKRP fukutin related protein
FLJ21369 uncharacterized protein FLJ21369
FOXC1 forkhead box C1
FOXO4 forkhead box O4
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GLYAT glycine-N-acyltransferase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPM6A glycoprotein M6A
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H2AFX H2A histone family, member X
HAB1 B1 for mucin
HOXA1 homeobox A1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDS iduronate 2-sulfatase
IGFBP4 insulin-like growth factor binding protein 4
INSL4 insulin-like 4 (placenta)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF1A kinesin family member 1A
KYNU kynureninase
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LTB4R leukotriene B4 receptor
MARC1 mitochondrial amidoxime reducing component 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL3 muscleblind-like splicing regulator 3
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MMP19 matrix metallopeptidase 19
MORN1 MORN repeat containing 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCLN nicalin
NEK11 NIMA-related kinase 11
NOX1 NADPH oxidase 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PGAM2 phosphoglycerate mutase 2 (muscle)
PLCD1 phospholipase C, delta 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RGS5 regulator of G-protein signaling 5
RNF19B ring finger protein 19B
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RORA RAR-related orphan receptor A
RPL13P5 ribosomal protein L13 pseudogene 5
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SCLY selenocysteine lyase
SFTPB surfactant protein B
SH3BP1 SH3-domain binding protein 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SMTN smoothelin
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SORBS3 sorbin and SH3 domain containing 3
SOX12 SRY (sex determining region Y)-box 12
SPATA5L1 spermatogenesis associated 5-like 1
SSTR4 somatostatin receptor 4
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYCP2 synaptonemal complex protein 2
TK2 thymidine kinase 2, mitochondrial
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRIM62 tripartite motif containing 62
WNT2B wingless-type MMTV integration site family, member 2B
WSCD1 WSC domain containing 1
ZNF446 zinc finger protein 446
ZNF646 zinc finger protein 646
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACO1 aconitase 1, soluble
ADAM15 ADAM metallopeptidase domain 15
ADGRA3 adhesion G protein-coupled receptor A3
ADGRE1 adhesion G protein-coupled receptor E1
AEN apoptosis enhancing nuclease
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP7B ATPase, Cu++ transporting, beta polypeptide
BHLHE41 basic helix-loop-helix family, member e41
BNC2 basonuclin 2
BTBD18 BTB (POZ) domain containing 18
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CCDC71 coiled-coil domain containing 71
CD300C CD300c molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK3 cyclin-dependent kinase 3
CIDEC cell death-inducing DFFA-like effector c
COL9A2 collagen, type IX, alpha 2
CXORF56 chromosome X open reading frame 56
DGKG diacylglycerol kinase, gamma 90kDa
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPY19L2P2 DPY19L2 pseudogene 2
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
EML4 echinoderm microtubule associated protein like 4
ERO1LB ERO1-like beta (S. cerevisiae)
FAM102A family with sequence similarity 102, member A
FGL1 fibrinogen-like 1
FJX1 four jointed box 1 (Drosophila)
FKBP9 FK506 binding protein 9, 63 kDa
GJA8 gap junction protein, alpha 8, 50kDa
GTF2I general transcription factor IIi
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HDAC9 histone deacetylase 9
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI6 interferon, alpha-inducible protein 6
IL3RA interleukin 3 receptor, alpha (low affinity)
IMPAD1 inositol monophosphatase domain containing 1
IREB2 iron-responsive element binding protein 2
KLHL36 kelch-like family member 36
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIMD2 LIM domain containing 2
LINS lines homolog (Drosophila)
LPAR6 lysophosphatidic acid receptor 6
LY6E lymphocyte antigen 6 complex, locus E
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MYBBP1A MYB binding protein (P160) 1a
MYBPH myosin binding protein H
NCS1 neuronal calcium sensor 1
NTSR1 neurotensin receptor 1 (high affinity)
NUBP2 nucleotide binding protein 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXPH4 neurexophilin 4
PADI1 peptidyl arginine deiminase, type I
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PDZD7 PDZ domain containing 7
PECR peroxisomal trans-2-enoyl-CoA reductase
POLL polymerase (DNA directed), lambda
POTEKP POTE ankyrin domain family, member K, pseudogene
PRSS53 protease, serine, 53
QPCTL glutaminyl-peptide cyclotransferase-like
QTRT1 queuine tRNA-ribosyltransferase 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
SALL2 spalt-like transcription factor 2
SBNO2 strawberry notch homolog 2 (Drosophila)
SETD1A SET domain containing 1A
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
STEAP3 STEAP family member 3, metalloreductase
STX11 syntaxin 11
STX17 syntaxin 17
SYNJ2BP synaptojanin 2 binding protein
THBS3 thrombospondin 3
THBS4 thrombospondin 4
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TMEM206 transmembrane protein 206
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRDMT1 tRNA aspartic acid methyltransferase 1
UNC119 unc-119 homolog (C. elegans)
VEGFC vascular endothelial growth factor C
WNT16 wingless-type MMTV integration site family, member 16
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF137P zinc finger protein 137, pseudogene
ZNF141 zinc finger protein 141
ZNF250 zinc finger protein 250
ZNF345 zinc finger protein 345
ZNF354A zinc finger protein 354A
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493
ZNF816 zinc finger protein 816