end stage renal failure Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:783
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Genes

188 genes associated with the disease end stage renal failure in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
ADCY5 adenylate cyclase 5 1.99917
HMGA2 high mobility group AT-hook 2 1.98999
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.94711
MAP3K15 mitogen-activated protein kinase kinase kinase 15 1.59789
LCORL ligand dependent nuclear receptor corepressor-like 1.59609
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 1.5887
MYH9 myosin, heavy chain 9, non-muscle 1.53195
ADRB1 adrenoceptor beta 1 1.46277
RNF185 ring finger protein 185 1.38293
LIMK2 LIM domain kinase 2 1.37259
PDE3A phosphodiesterase 3A, cGMP-inhibited 1.30499
ENOX1 ecto-NOX disulfide-thiol exchanger 1 1.3021
LARGE like-glycosyltransferase 1.28906
PDZRN3 PDZ domain containing ring finger 3 1.23034
CHN2 chimerin 2 1.22504
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.21996
GRIK2 glutamate receptor, ionotropic, kainate 2 1.16089
PVT1 Pvt1 oncogene (non-protein coding) 1.14463
GAS2 growth arrest-specific 2 1.14463
ZBTB20 zinc finger and BTB domain containing 20 1.14027
CENPM centromere protein M 1.10764
CARS cysteinyl-tRNA synthetase 1.10555
PTPRM protein tyrosine phosphatase, receptor type, M 1.07599
STEAP1B STEAP family member 1B 1.07599
SORBS1 sorbin and SH3 domain containing 1 1.06224
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.04846
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.04846
PCSK2 proprotein convertase subtilisin/kexin type 2 1.04846
NRG1 neuregulin 1 1.00407
ELMO1 engulfment and cell motility 1 0.986376
SH3BP4 SH3-domain binding protein 4 0.971169
UNC5C unc-5 homolog C (C. elegans) 0.946163
CDC6 cell division cycle 6 0.942098
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.917442
C6ORF10 chromosome 6 open reading frame 10 0.912987
LOC100132891 0.905653
LOC100294145 uncharacterized LOC100294145 0.905653
TBC1D22A TBC1 domain family, member 22A 0.889009
TBC1D14 TBC1 domain family, member 14 0.884624
SMYD3 SET and MYND domain containing 3 0.876818
PDE5A phosphodiesterase 5A, cGMP-specific 0.874542
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.874542
PRRC2A proline-rich coiled-coil 2A 0.858922
FAM134B family with sequence similarity 134, member B 0.853791
KAZN kazrin, periplakin interacting protein 0.826866
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.812342
MARCH11 membrane-associated ring finger (C3HC4) 11 0.794247
NCALD neurocalcin delta 0.794247
MACF1 microtubule-actin crosslinking factor 1 0.788564
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.783178
FAM189A1 family with sequence similarity 189, member A1 0.775739
ISM1 isthmin 1, angiogenesis inhibitor 0.775452
IL12RB1 interleukin 12 receptor, beta 1 0.77291
DNAH11 dynein, axonemal, heavy chain 11 0.772631
TBC1D31 TBC1 domain family, member 31 0.77125
NTN1 netrin 1 0.76582
FGF12 fibroblast growth factor 12 0.753954
MTUS1 microtubule associated tumor suppressor 1 0.752399
OR2L13 olfactory receptor, family 2, subfamily L, member 13 0.749856
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.748112
MYO5B myosin VB 0.737101
TMEM63C transmembrane protein 63C 0.729362
NRXN1 neurexin 1 0.728903
SCOC short coiled-coil protein 0.727087
SH2D4A SH2 domain containing 4A 0.726862
LOC645513 uncharacterized LOC645513 0.724858
RNF17 ring finger protein 17 0.718432
ZNF202 zinc finger protein 202 0.718432
GAP43 growth associated protein 43 0.714351
LOC284661 uncharacterized LOC284661 0.712368
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.711195
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.70719
NRXN3 neurexin 3 0.706444
NEGR1 neuronal growth regulator 1 0.704419
FABP2 fatty acid binding protein 2, intestinal 0.69773
ZMIZ1 zinc finger, MIZ-type containing 1 0.696042
NBN nibrin 0.689711
DNAH5 dynein, axonemal, heavy chain 5 0.686153
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.683009
PEX7 peroxisomal biogenesis factor 7 0.679107
CERS6 ceramide synthase 6 0.67359
VWDE von Willebrand factor D and EGF domains 0.672922
ADD1 adducin 1 (alpha) 0.671336
SIK3 SIK family kinase 3 0.667834
CTIF CBP80/20-dependent translation initiation factor 0.666845
CADM4 cell adhesion molecule 4 0.664902
LOC63930 uncharacterized LOC63930 0.662072
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 0.66115
ZNF714 zinc finger protein 714 0.660239
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.657565
ACSS3 acyl-CoA synthetase short-chain family member 3 0.657565
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 0.652472
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.650844
MACROD2 MACRO domain containing 2 0.650043
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.650043
KRT35 keratin 35, type I 0.649249
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.648464
KRT2 keratin 2, type II 0.647686
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.64313
ALPK1 alpha-kinase 1 0.638972
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.638472
SDK1 sidekick cell adhesion molecule 1 0.637975
CFAP61 cilia and flagella associated protein 61 0.637975
SH2D4B SH2 domain containing 4B 0.637483
PHACTR1 phosphatase and actin regulator 1 0.637483
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.633226
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.633226
CDH8 cadherin 8, type 2 0.632771
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.63232
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.627273
NEB nebulin 0.627273
CDH13 cadherin 13 0.62609
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.625701
GRIP1 glutamate receptor interacting protein 1 0.621951
GRAMD3 GRAM domain containing 3 0.62159
EPB41 erythrocyte membrane protein band 4.1 0.62123
RGS6 regulator of G-protein signaling 6 0.619815
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.619815
LRP1B low density lipoprotein receptor-related protein 1B 0.617086
BID BH3 interacting domain death agonist 0.615118
TLE3 transducin-like enhancer of split 3 0.615118
MUC4 mucin 4, cell surface associated 0.614766
RAI14 retinoic acid induced 14 0.614416
NELL1 NEL-like 1 (chicken) 0.614068
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.613378
ZNF697 zinc finger protein 697 0.612021
EYA1 EYA transcriptional coactivator and phosphatase 1 0.611686
CRBN cereblon 0.609075
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.608124
KRT33B keratin 33B, type I 0.606572
CTNND2 catenin (cadherin-associated protein), delta 2 0.60566
FMN2 formin 2 0.60417
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.602717
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.602145
AGBL1 ATP/GTP binding protein-like 1 0.601861
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.601861
MMS22L MMS22-like, DNA repair protein 0.601579
SIDT2 SID1 transmembrane family, member 2 0.601579
MGC27382 uncharacterized MGC27382 0.601018
KRTAP16-1 keratin associated protein 16-1 0.599913
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.596524
RABGAP1L RAB GTPase activating protein 1-like 0.59596
WDR1 WD repeat domain 1 0.595401
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.594024
PLCD3 phospholipase C, delta 3 0.592677
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.591098
SCG3 secretogranin III 0.591098
DNAH12 dynein, axonemal, heavy chain 12 0.589811
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene 0.589557
RRBP1 ribosome binding protein 1 0.589052
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.586345
WWOX WW domain containing oxidoreductase 0.585152
EXOSC3 exosome component 3 0.584916
PARD6B par-6 family cell polarity regulator beta 0.584916
SV2C synaptic vesicle glycoprotein 2C 0.583982
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.583291
ANK2 ankyrin 2, neuronal 0.58124
WDR17 WD repeat domain 17 0.58124
ACOX3 acyl-CoA oxidase 3, pristanoyl 0.58076
UNC13C unc-13 homolog C (C. elegans) 0.58076
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.580283
FRMD4A FERM domain containing 4A 0.580046
C3ORF67 chromosome 3 open reading frame 67 0.578411
PQBP1 polyglutamine binding protein 1 0.573953
FAM107B family with sequence similarity 107, member B 0.571211
PTN pleiotrophin 0.571005
ADD3 adducin 3 (gamma) 0.5708
YPEL1 yippee-like 1 (Drosophila) 0.570595
F9 coagulation factor IX 0.569984
FHOD3 formin homology 2 domain containing 3 0.564921
BAG1 BCL2-associated athanogene 0.563624
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.563624
THBS4 thrombospondin 4 0.552035
TELO2 telomere maintenance 2 0.54738
TMPO thymopoietin 0.547225
BMPR1B bone morphogenetic protein receptor, type IB 0.544152
ZNF180 zinc finger protein 180 0.532281
ITGA1 integrin, alpha 1 0.52866
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 0.527413
VWF von Willebrand factor 0.51399
SGK223 homolog of rat pragma of Rnd2 0.506889
C4ORF33 chromosome 4 open reading frame 33 0.506247
ALS2CL ALS2 C-terminal like 0.50423
COL4A1 collagen, type IV, alpha 1 0.503149
COL5A1 collagen, type V, alpha 1 0.503149
GRHL2 grainyhead-like 2 (Drosophila) 0.502485
BMP5 bone morphogenetic protein 5 0.499285
CHD9 chromodomain helicase DNA binding protein 9 0.498362