enalapril-7026 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the enalapril-7026 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHCYL2 adenosylhomocysteinase-like 2
AK1 adenylate kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMCX4 armadillo repeat containing, X-linked 4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BBS9 Bardet-Biedl syndrome 9
BIN1 bridging integrator 1
C10ORF95 chromosome 10 open reading frame 95
CAPN10 calpain 10
CCDC69 coiled-coil domain containing 69
CEP162 centrosomal protein 162kDa
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL11A2 collagen, type XI, alpha 2
CUZD1 CUB and zona pellucida-like domains 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DEPDC5 DEP domain containing 5
DLX4 distal-less homeobox 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EFNB3 ephrin-B3
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GRB10 growth factor receptor-bound protein 10
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GYG2 glycogenin 2
HEXA hexosaminidase A (alpha polypeptide)
HOXB7 homeobox B7
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
IL17RA interleukin 17 receptor A
INTS7 integrator complex subunit 7
JUN jun proto-oncogene
KIAA1456 KIAA1456
KLF11 Kruppel-like factor 11
KLK5 kallikrein-related peptidase 5
LIF leukemia inhibitory factor
LINC00341 long intergenic non-protein coding RNA 341
LRRC6 leucine rich repeat containing 6
LZTR1 leucine-zipper-like transcription regulator 1
MCC mutated in colorectal cancers
MCM3AP minichromosome maintenance complex component 3 associated protein
MKL1 megakaryoblastic leukemia (translocation) 1
MLX MLX, MAX dimerization protein
MRPS18C mitochondrial ribosomal protein S18C
MTMR2 myotubularin related protein 2
MTMR3 myotubularin related protein 3
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NMBR neuromedin B receptor
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUMA1 nuclear mitotic apparatus protein 1
NXPH4 neurexophilin 4
OASL 2'-5'-oligoadenylate synthetase-like
ORAI2 ORAI calcium release-activated calcium modulator 2
PADI1 peptidyl arginine deiminase, type I
PGPEP1 pyroglutamyl-peptidase I
PHEX phosphate regulating endopeptidase homolog, X-linked
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLAGL1 pleiomorphic adenoma gene-like 1
POFUT1 protein O-fucosyltransferase 1
PPAP2B phosphatidic acid phosphatase type 2B
PROL1 proline rich, lacrimal 1
RAD52 RAD52 homolog (S. cerevisiae)
RNF39 ring finger protein 39
RPLP2 ribosomal protein, large, P2
RRBP1 ribosome binding protein 1
RXRB retinoid X receptor, beta
S100A2 S100 calcium binding protein A2
SBNO2 strawberry notch homolog 2 (Drosophila)
SDC3 syndecan 3
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3D21 SH3 domain containing 21
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLIT2 slit homolog 2 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
STC1 stanniocalcin 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TADA3 transcriptional adaptor 3
TAPBP TAP binding protein (tapasin)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TLDC1 TBC/LysM-associated domain containing 1
TMEM63A transmembrane protein 63A
TMPRSS2 transmembrane protease, serine 2
TOP3B topoisomerase (DNA) III beta
TXNL4A thioredoxin-like 4A
UTRN utrophin
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPRBP Vpr (HIV-1) binding protein
WLS wntless Wnt ligand secretion mediator
ZFX zinc finger protein, X-linked
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANXA2P3 annexin A2 pseudogene 3
ARMC7 armadillo repeat containing 7
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS7 Bardet-Biedl syndrome 7
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
C19ORF24 chromosome 19 open reading frame 24
C2CD2 C2 calcium-dependent domain containing 2
C3ORF52 chromosome 3 open reading frame 52
C9ORF114 chromosome 9 open reading frame 114
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA2 calmodulin binding transcription activator 2
CARD8 caspase recruitment domain family, member 8
CBR4 carbonyl reductase 4
CENPC centromere protein C
CENPJ centromere protein J
CEP72 centrosomal protein 72kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CLDND1 claudin domain containing 1
CLSPN claspin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COL4A5 collagen, type IV, alpha 5
CTC1 CTS telomere maintenance complex component 1
CTSK cathepsin K
CUEDC1 CUE domain containing 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DGKD diacylglycerol kinase, delta 130kDa
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DSE dermatan sulfate epimerase
DUSP5 dual specificity phosphatase 5
ECHDC2 enoyl CoA hydratase domain containing 2
ETAA1 Ewing tumor-associated antigen 1
FOSL1 FOS-like antigen 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HPS6 Hermansky-Pudlak syndrome 6
IL15RA interleukin 15 receptor, alpha
IP6K1 inositol hexakisphosphate kinase 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IQSEC2 IQ motif and Sec7 domain 2
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAT2B K(lysine) acetyltransferase 2B
KLF3 Kruppel-like factor 3 (basic)
LAMB2 laminin, beta 2 (laminin S)
LINC00115 long intergenic non-protein coding RNA 115
LRRC37A2 leucine rich repeat containing 37, member A2
LYPD1 LY6/PLAUR domain containing 1
MAMLD1 mastermind-like domain containing 1
MANBA mannosidase, beta A, lysosomal
MIS18BP1 MIS18 binding protein 1
MNS1 meiosis-specific nuclear structural 1
MNX1 motor neuron and pancreas homeobox 1
MT1HL1 metallothionein 1H-like 1
MYO1E myosin IE
NBEAL2 neurobeachin-like 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NECAP2 NECAP endocytosis associated 2
NLK nemo-like kinase
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCDHA6 protocadherin alpha 6
PGS1 phosphatidylglycerophosphate synthase 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB5C RAB5C, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBL1 retinoblastoma-like 1
REPS2 RALBP1 associated Eps domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF123 ring finger protein 123
RNF170 ring finger protein 170
RNF38 ring finger protein 38
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD3 RWD domain containing 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A40 solute carrier family 25, member 40
SLC35F6 solute carrier family 35, member F6
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREBF2 sterol regulatory element binding transcription factor 2
TM7SF3 transmembrane 7 superfamily member 3
TMEM57 transmembrane protein 57
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TWF2 twinfilin actin binding protein 2
UBXN6 UBX domain protein 6
USP18 ubiquitin specific peptidase 18
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF8 zinc finger protein 8