embryo tissue necrosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage (Mammalian Phenotype Ontology, MP_0013241)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013241
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Genes

35 gene mutations causing the embryo tissue necrosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CSK c-src tyrosine kinase
DLC1 DLC1 Rho GTPase activating protein
DLL4 delta-like 4 (Drosophila)
ENG endoglin
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
FXN frataxin
G6PD glucose-6-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCM1 glial cells missing homolog 1 (Drosophila)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
ISL1 ISL LIM homeobox 1
JAG1 jagged 1
KDR kinase insert domain receptor
KLF2 Kruppel-like factor 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MTTP microsomal triglyceride transfer protein
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOA1 nitric oxide associated 1
NUMB numb homolog (Drosophila)
PISD phosphatidylserine decarboxylase
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RDH10 retinol dehydrogenase 10 (all-trans)
RHEB Ras homolog enriched in brain
RUNX1 runt-related transcription factor 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
TAL1 T-cell acute lymphocytic leukemia 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
XBP1 X-box binding protein 1