A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA, and exerts direct effects on transcriptional elongation and exocytosis. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes. (Gene Ontology, GO_0033588)
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6 proteins localized to the elongator holoenzyme complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.