eldeline-6026 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the eldeline-6026 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADGRE1 adhesion G protein-coupled receptor E1
APOE apolipoprotein E
ARTN artemin
ATN1 atrophin 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CAPN2 calpain 2, (m/II) large subunit
CAPZB capping protein (actin filament) muscle Z-line, beta
CCR1 chemokine (C-C motif) receptor 1
CCR7 chemokine (C-C motif) receptor 7
CD47 CD47 molecule
CDK13 cyclin-dependent kinase 13
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL11A1 collagen, type XI, alpha 1
COL13A1 collagen, type XIII, alpha 1
CREBBP CREB binding protein
CUL3 cullin 3
DAO D-amino-acid oxidase
DCN decorin
DLK2 delta-like 2 homolog (Drosophila)
DNAI2 dynein, axonemal, intermediate chain 2
DOCK6 dedicator of cytokinesis 6
DPF1 D4, zinc and double PHD fingers family 1
DSCC1 DNA replication and sister chromatid cohesion 1
ECEL1 endothelin converting enzyme-like 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FAM212B family with sequence similarity 212, member B
FN1 fibronectin 1
FST follistatin
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GRIA4 glutamate receptor, ionotropic, AMPA 4
GSK3A glycogen synthase kinase 3 alpha
HOXA1 homeobox A1
HPX hemopexin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL1R2 interleukin 1 receptor, type II
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KANK1 KN motif and ankyrin repeat domains 1
KRT6B keratin 6B, type II
KRT75 keratin 75, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LEFTY1 left-right determination factor 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMF2 lipase maturation factor 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD2 methyl-CpG binding domain protein 2
MCTP1 multiple C2 domains, transmembrane 1
MED25 mediator complex subunit 25
MIER2 mesoderm induction early response 1, family member 2
MRPL41 mitochondrial ribosomal protein L41
MYOZ1 myozenin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NRF1 nuclear respiratory factor 1
NYNRIN NYN domain and retroviral integrase containing
OBSL1 obscurin-like 1
OLFML2A olfactomedin-like 2A
OR2B2 olfactory receptor, family 2, subfamily B, member 2
PDE4A phosphodiesterase 4A, cAMP-specific
PDIA2 protein disulfide isomerase family A, member 2
PKP2 plakophilin 2
PLK3 polo-like kinase 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRAMEF11 PRAME family member 11
PRLH prolactin releasing hormone
PTAFR platelet-activating factor receptor
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RANBP3 RAN binding protein 3
RB1 retinoblastoma 1
RGS12 regulator of G-protein signaling 12
RNASE4 ribonuclease, RNase A family, 4
RORC RAR-related orphan receptor C
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RTN2 reticulon 2
SATB2 SATB homeobox 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2B1 SH2B adaptor protein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNCAIP synuclein, alpha interacting protein
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SSX3 synovial sarcoma, X breakpoint 3
TBCD tubulin folding cofactor D
THY1 Thy-1 cell surface antigen
TLE2 transducin-like enhancer of split 2
TLR3 toll-like receptor 3
TMPRSS6 transmembrane protease, serine 6
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28

decreased expression

Symbol Name
ACTL8 actin-like 8
ADGRE5 adhesion G protein-coupled receptor E5
ADTRP androgen-dependent TFPI-regulating protein
AHNAK2 AHNAK nucleoprotein 2
ALPK1 alpha-kinase 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATG10 autophagy related 10
AUTS2 autism susceptibility candidate 2
C11ORF80 chromosome 11 open reading frame 80
C17ORF80 chromosome 17 open reading frame 80
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CD82 CD82 molecule
CD8A CD8a molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLDN17 claudin 17
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
CPB1 carboxypeptidase B1 (tissue)
CTSF cathepsin F
CYHR1 cysteine/histidine-rich 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EN2 engrailed homeobox 2
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAAH fatty acid amide hydrolase
FGD6 FYVE, RhoGEF and PH domain containing 6
FGL1 fibrinogen-like 1
FOXI1 forkhead box I1
GPATCH2L G patch domain containing 2-like
GPR19 G protein-coupled receptor 19
HDAC5 histone deacetylase 5
HIST1H4E histone cluster 1, H4e
IDI2-AS1 IDI2 antisense RNA 1
IQSEC2 IQ motif and Sec7 domain 2
ITGA10 integrin, alpha 10
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD7 potassium channel tetramerization domain containing 7
KREMEN2 kringle containing transmembrane protein 2
LHX6 LIM homeobox 6
LMX1B LIM homeobox transcription factor 1, beta
LONRF3 LON peptidase N-terminal domain and ring finger 3
MALL mal, T-cell differentiation protein-like
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MED9 mediator complex subunit 9
METTL16 methyltransferase like 16
MORN1 MORN repeat containing 1
MSI1 musashi RNA-binding protein 1
MUC3A mucin 3A, cell surface associated
MYL5 myosin, light chain 5, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NNAT neuronatin
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NRSN2 neurensin 2
OSMR oncostatin M receptor
PDE5A phosphodiesterase 5A, cGMP-specific
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PQLC2 PQ loop repeat containing 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRPH peripherin
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFXAP regulatory factor X-associated protein
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A14 solute carrier family 22, member 14
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
STAG3 stromal antigen 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
STRA6 stimulated by retinoic acid 6
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM180 transmembrane protein 180
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM5 tripartite motif containing 5
UNC119 unc-119 homolog (C. elegans)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEZT vezatin, adherens junctions transmembrane protein
WDR33 WD repeat domain 33
XYLT2 xylosyltransferase II
ZNF16 zinc finger protein 16
ZNF480 zinc finger protein 480
ZNF532 zinc finger protein 532
ZNF552 zinc finger protein 552