eldeline-2171 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the eldeline-2171 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANGEL2 angel homolog 2 (Drosophila)
APOC4 apolipoprotein C-IV
AQP9 aquaporin 9
AREG amphiregulin
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATP9B ATPase, class II, type 9B
C19ORF73 chromosome 19 open reading frame 73
CABP1 calcium binding protein 1
CCR4 chemokine (C-C motif) receptor 4
CD200 CD200 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CIZ1 CDKN1A interacting zinc finger protein 1
COL18A1 collagen, type XVIII, alpha 1
COL19A1 collagen, type XIX, alpha 1
COPE coatomer protein complex, subunit epsilon
CPNE7 copine VII
CTIF CBP80/20-dependent translation initiation factor
CTSV cathepsin V
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSPP dentin sialophosphoprotein
EPS8L3 EPS8-like 3
FSHB follicle stimulating hormone, beta polypeptide
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPATCH4 G patch domain containing 4
GPC1 glypican 1
GPR132 G protein-coupled receptor 132
HFE hemochromatosis
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA10 homeobox A10
IL36G interleukin 36, gamma
IMPG2 interphotoreceptor matrix proteoglycan 2
JPH3 junctophilin 3
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LMF1 lipase maturation factor 1
LOXL3 lysyl oxidase-like 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MASP2 mannan-binding lectin serine peptidase 2
MET MET proto-oncogene, receptor tyrosine kinase
MMP19 matrix metallopeptidase 19
MOGAT2 monoacylglycerol O-acyltransferase 2
MTCP1 mature T-cell proliferation 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NADK NAD kinase
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NDRG2 NDRG family member 2
NRG2 neuregulin 2
NUAK1 NUAK family, SNF1-like kinase, 1
OSBPL10 oxysterol binding protein-like 10
OXCT2 3-oxoacid CoA transferase 2
PEX16 peroxisomal biogenesis factor 16
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLAT plasminogen activator, tissue
PLCL1 phospholipase C-like 1
POFUT1 protein O-fucosyltransferase 1
POLL polymerase (DNA directed), lambda
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM10 PR domain containing 10
PRKCH protein kinase C, eta
PRPF18 pre-mRNA processing factor 18
PRR5 proline rich 5 (renal)
PTCRA pre T-cell antigen receptor alpha
PYGB phosphorylase, glycogen; brain
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RDH16 retinol dehydrogenase 16 (all-trans)
RHEB Ras homolog enriched in brain
RIMS2 regulating synaptic membrane exocytosis 2
RNF39 ring finger protein 39
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SH2D4A SH2 domain containing 4A
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SMAD3 SMAD family member 3
SOCS3 suppressor of cytokine signaling 3
SPAG6 sperm associated antigen 6
SRPX sushi-repeat containing protein, X-linked
STK11 serine/threonine kinase 11
TAOK2 TAO kinase 2
TFF2 trefoil factor 2
TGFA transforming growth factor, alpha
THBS2 thrombospondin 2
THSD7A thrombospondin, type I, domain containing 7A
TMEM8B transmembrane protein 8B
TNIK TRAF2 and NCK interacting kinase
TRIM3 tripartite motif containing 3
TRMT61A tRNA methyltransferase 61A
WRAP53 WD repeat containing, antisense to TP53
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ACP6 acid phosphatase 6, lysophosphatidic
ADGRG2 adhesion G protein-coupled receptor G2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BAG4 BCL2-associated athanogene 4
BTBD18 BTB (POZ) domain containing 18
C5AR1 complement component 5a receptor 1
C5ORF45 chromosome 5 open reading frame 45
CBX7 chromobox homolog 7
CCDC132 coiled-coil domain containing 132
CDH10 cadherin 10, type 2 (T2-cadherin)
CEP131 centrosomal protein 131kDa
CEP72 centrosomal protein 72kDa
CORT cortistatin
DDN dendrin
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DEPDC5 DEP domain containing 5
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNM3 dynamin 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EIF5A2 eukaryotic translation initiation factor 5A2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FKBPL FK506 binding protein like
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPR22 G protein-coupled receptor 22
GPRASP1 G protein-coupled receptor associated sorting protein 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BC histone cluster 1, H2bc
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL12RB1 interleukin 12 receptor, beta 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0754 KIAA0754
KIF24 kinesin family member 24
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KPNA5 karyopherin alpha 5 (importin alpha 6)
LOC729164 hCG1732469
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MCTP2 multiple C2 domains, transmembrane 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MKRN3 makorin ring finger protein 3
MTL5 metallothionein-like 5, testis-specific (tesmin)
PCDHGA10 protocadherin gamma subfamily A, 10
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PLP1 proteolipid protein 1
PNOC prepronociceptin
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PYHIN1 pyrin and HIN domain family, member 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAP1GAP2 RAP1 GTPase activating protein 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRAGB Ras-related GTP binding B
SCD5 stearoyl-CoA desaturase 5
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SGPP1 sphingosine-1-phosphate phosphatase 1
SIDT1 SID1 transmembrane family, member 1
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAI1 snail family zinc finger 1
SPATA1 spermatogenesis associated 1
STRN striatin, calmodulin binding protein
STX11 syntaxin 11
SYNDIG1 synapse differentiation inducing 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TCTN2 tectonic family member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TMC7 transmembrane channel-like 7
TMEM57 transmembrane protein 57
TPM3 tropomyosin 3
TRIM45 tripartite motif containing 45
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
TUBA4B tubulin, alpha 4b
TXLNG taxilin gamma
UBQLN4 ubiquilin 4
USP6NL USP6 N-terminal like
WDR91 WD repeat domain 91
WNT16 wingless-type MMTV integration site family, member 16
ZBTB6 zinc finger and BTB domain containing 6
ZNF177 zinc finger protein 177
ZNF354A zinc finger protein 354A
ZNF76 zinc finger protein 76
ZSCAN16 zinc finger and SCAN domain containing 16