egfr Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. (Gene Ontology, GO_0005006)
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Genes

136 proteins co-occuring with the biological term egfr in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACTN4 actinin, alpha 4
ADRBK1 adrenergic, beta, receptor kinase 1
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKTIP AKT interacting protein
ANXA1 annexin A1
AR androgen receptor
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ATM ATM serine/threonine kinase
AXL AXL receptor tyrosine kinase
BCAR1 breast cancer anti-estrogen resistance 1
BCR breakpoint cluster region
BDKRB2 bradykinin receptor B2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCAR1 cell division cycle and apoptosis regulator 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFL1 cofilin 1 (non-muscle)
CHKA choline kinase alpha
CLIP1 CAP-GLY domain containing linker protein 1
CLTC clathrin, heavy chain (Hc)
CREB1 cAMP responsive element binding protein 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTTN cortactin
DOCK1 dedicator of cytokinesis 1
DOK2 docking protein 2, 56kDa
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPB41 erythrocyte membrane protein band 4.1
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FOXO1 forkhead box O1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GJA1 gap junction protein, alpha 1, 43kDa
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
HBEGF heparin-binding EGF-like growth factor
HDAC6 histone deacetylase 6
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIP1 huntingtin interacting protein 1
HIST1H3A histone cluster 1, H3a
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IQGAP1 IQ motif containing GTPase activating protein 1
IRF3 interferon regulatory factor 3
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LRP6 low density lipoprotein receptor-related protein 6
LRRK1 leucine-rich repeat kinase 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MCM7 minichromosome maintenance complex component 7
MET MET proto-oncogene, receptor tyrosine kinase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR1I3 nuclear receptor subfamily 1, group I, member 3
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCNA proliferating cell nuclear antigen
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PGR progesterone receptor
PIKFYVE phosphoinositide kinase, FYVE finger containing
PKM pyruvate kinase, muscle
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PNPT1 polyribonucleotide nucleotidyltransferase 1
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRE protein tyrosine phosphatase, receptor type, E
PXN paxillin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS16 regulator of G-protein signaling 16
RIPK2 receptor-interacting serine-threonine kinase 2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF1 serine/arginine-rich splicing factor 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TGM2 transglutaminase 2
TLR3 toll-like receptor 3
TOM1L1 target of myb1 (chicken)-like 1
TP53 tumor protein p53
USP8 ubiquitin specific peptidase 8
WASL Wiskott-Aldrich syndrome-like
WBP2 WW domain binding protein 2
YBX1 Y box binding protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE28 zinc finger, FYVE domain containing 28