econazole-7305 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the econazole-7305 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ALAS1 5'-aminolevulinate synthase 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BMP8A bone morphogenetic protein 8a
CAPN3 calpain 3, (p94)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN17 claudin 17
CNTNAP3B contactin associated protein-like 3B
COG5 component of oligomeric golgi complex 5
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
CPT1A carnitine palmitoyltransferase 1A (liver)
CSF1 colony stimulating factor 1 (macrophage)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND2A DENN/MADD domain containing 2A
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK9 dedicator of cytokinesis 9
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
FAM46A family with sequence similarity 46, member A
FAM69A family with sequence similarity 69, member A
FLJ11292
GADD45B growth arrest and DNA-damage-inducible, beta
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HDAC9 histone deacetylase 9
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOMER3 homer scaffolding protein 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IL4R interleukin 4 receptor
IL6 interleukin 6
INADL InaD-like (Drosophila)
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
JUN jun proto-oncogene
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCTD17 potassium channel tetramerization domain containing 17
KDM6A lysine (K)-specific demethylase 6A
KLF4 Kruppel-like factor 4 (gut)
LINC00597 long intergenic non-protein coding RNA 597
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MARS methionyl-tRNA synthetase
MFAP3 microfibrillar-associated protein 3
MKL1 megakaryoblastic leukemia (translocation) 1
MTA1 metastasis associated 1
MX1 MX dynamin-like GTPase 1
N4BP1 NEDD4 binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NID2 nidogen 2 (osteonidogen)
NNMT nicotinamide N-methyltransferase
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
OTUD4 OTU deubiquitinase 4
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDHA9 protocadherin alpha 9
PLXNA1 plexin A1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RGS10 regulator of G-protein signaling 10
RGS4 regulator of G-protein signaling 4
RPL7 ribosomal protein L7
SAMD9 sterile alpha motif domain containing 9
SLC35G2 solute carrier family 35, member G2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMR3A submaxillary gland androgen regulated protein 3A
SPIDR scaffolding protein involved in DNA repair
SQSTM1 sequestosome 1
SS18 synovial sarcoma translocation, chromosome 18
STAT1 signal transducer and activator of transcription 1, 91kDa
SYT11 synaptotagmin XI
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TIAM1 T-cell lymphoma invasion and metastasis 1
TK2 thymidine kinase 2, mitochondrial
TMCC1 transmembrane and coiled-coil domain family 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK1 tyrosine kinase, non-receptor, 1
TTC12 tetratricopeptide repeat domain 12
ZC3H7B zinc finger CCCH-type containing 7B
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF222 zinc finger protein 222

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AEN apoptosis enhancing nuclease
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGAP12 Rho GTPase activating protein 12
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BAHCC1 BAH domain and coiled-coil containing 1
BCAS3 breast carcinoma amplified sequence 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTD biotinidase
C11ORF71 chromosome 11 open reading frame 71
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
CA5BP1 carbonic anhydrase VB pseudogene 1
CCNJL cyclin J-like
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP85 centrosomal protein 85kDa
CLDN15 claudin 15
COCH cochlin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTSF cathepsin F
CUEDC1 CUE domain containing 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
EFNA3 ephrin-A3
EGF epidermal growth factor
EPN3 epsin 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM102A family with sequence similarity 102, member A
FBXL15 F-box and leucine-rich repeat protein 15
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HCFC2 host cell factor C2
HIST1H2AJ histone cluster 1, H2aj
HOXB5 homeobox B5
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
JMJD4 jumonji domain containing 4
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KRT8P12 keratin 8 pseudogene 12
LYPD1 LY6/PLAUR domain containing 1
MAMLD1 mastermind-like domain containing 1
MCM10 minichromosome maintenance complex component 10
MCOLN1 mucolipin 1
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MEIS1 Meis homeobox 1
MFSD12 major facilitator superfamily domain containing 12
MGC12488
MSRA methionine sulfoxide reductase A
NECAB3 N-terminal EF-hand calcium binding protein 3
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAX9 paired box 9
PCSK7 proprotein convertase subtilisin/kexin type 7
PEG3 paternally expressed 3
PEX26 peroxisomal biogenesis factor 26
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPL periplakin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPT2 palmitoyl-protein thioesterase 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
RIN1 Ras and Rab interactor 1
RUNDC3B RUN domain containing 3B
SALL2 spalt-like transcription factor 2
SCAI suppressor of cancer cell invasion
SDF2 stromal cell-derived factor 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHROOM2 shroom family member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNIP1 Smad nuclear interacting protein 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAR steroidogenic acute regulatory protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBXAS1 thromboxane A synthase 1 (platelet)
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN15 tetraspanin 15
USP27X ubiquitin specific peptidase 27, X-linked
USP6NL USP6 N-terminal like
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF415 zinc finger protein 415
ZNF702P zinc finger protein 702, pseudogene
ZNF711 zinc finger protein 711
ZNF787 zinc finger protein 787
ZSCAN31 zinc finger and SCAN domain containing 31