econazole-2396 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the econazole-2396 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACVR1B activin A receptor, type IB
ADGRD2 adhesion G protein-coupled receptor D2
ADGRF5 adhesion G protein-coupled receptor F5
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AFF2 AF4/FMR2 family, member 2
AGTPBP1 ATP/GTP binding protein 1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APAF1 apoptotic peptidase activating factor 1
ARHGAP35 Rho GTPase activating protein 35
ARRB2 arrestin, beta 2
ASGR2 asialoglycoprotein receptor 2
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC106 coiled-coil domain containing 106
CD300C CD300c molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEP170B centrosomal protein 170B
CFLAR CASP8 and FADD-like apoptosis regulator
CRABP2 cellular retinoic acid binding protein 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTNND1 catenin (cadherin-associated protein), delta 1
DDR1 discoidin domain receptor tyrosine kinase 1
DEFA4 defensin, alpha 4, corticostatin
DFNA5 deafness, autosomal dominant 5
DTX2 deltex 2, E3 ubiquitin ligase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELAC2 elaC ribonuclease Z 2
FAM189A1 family with sequence similarity 189, member A1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLIPR1 GLI pathogenesis-related 1
GPR35 G protein-coupled receptor 35
HBZ hemoglobin, zeta
HFE hemochromatosis
HGD homogentisate 1,2-dioxygenase
HOMER3 homer scaffolding protein 3
HPSE heparanase
HSPG2 heparan sulfate proteoglycan 2
ICA1 islet cell autoantigen 1, 69kDa
IGLJ3 immunoglobulin lambda joining 3
IL12RB1 interleukin 12 receptor, beta 1
IL1R2 interleukin 1 receptor, type II
KAZN kazrin, periplakin interacting protein
KCNIP1 Kv channel interacting protein 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LAMA2 laminin, alpha 2
LAT2 linker for activation of T cells family, member 2
LOC257152 uncharacterized LOC257152
LPAR2 lysophosphatidic acid receptor 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MED27 mediator complex subunit 27
MST1 macrophage stimulating 1
NEBL nebulette
NEK3 NIMA-related kinase 3
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PECR peroxisomal trans-2-enoyl-CoA reductase
PHTF2 putative homeodomain transcription factor 2
PIDD1 p53-induced death domain protein 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGES prostaglandin E synthase
PYGB phosphorylase, glycogen; brain
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RHOC ras homolog family member C
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SEC24D SEC24 family member D
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F6 solute carrier family 35, member F6
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPEF1 sperm flagellar 1
TBL2 transducin (beta)-like 2
TCEA2 transcription elongation factor A (SII), 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TK2 thymidine kinase 2, mitochondrial
TROVE2 TROVE domain family, member 2
TSC2 tuberous sclerosis 2
UBXN1 UBX domain protein 1
USP22 ubiquitin specific peptidase 22
WSB1 WD repeat and SOCS box containing 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF44 zinc finger protein 44
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADTRP androgen-dependent TFPI-regulating protein
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC4 armadillo repeat containing 4
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASPN asporin
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF95 chromosome 1 open reading frame 95
C9ORF9 chromosome 9 open reading frame 9
CASZ1 castor zinc finger 1
CCNE2 cyclin E2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CENPB centromere protein B, 80kDa
CEP295 centrosomal protein 295kDa
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CKB creatine kinase, brain
CTAGE9 CTAGE family, member 9
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYSLTR1 cysteinyl leukotriene receptor 1
DENND1C DENN/MADD domain containing 1C
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FLCN folliculin
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GGTLC1 gamma-glutamyltransferase light chain 1
GRAMD1B GRAM domain containing 1B
GRIP2 glutamate receptor interacting protein 2
GSTZ1 glutathione S-transferase zeta 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BE histone cluster 1, H2be
HIST1H4J histone cluster 1, H4j
HIST3H2A histone cluster 3, H2a
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
KLHL26 kelch-like family member 26
KLK15 kallikrein-related peptidase 15
KLK5 kallikrein-related peptidase 5
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTBP2 latent transforming growth factor beta binding protein 2
LYPLA2P1 lysophospholipase II pseudogene 1
MCMBP minichromosome maintenance complex binding protein
METTL2B methyltransferase like 2B
MON1B MON1 secretory trafficking family member B
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
NCS1 neuronal calcium sensor 1
NFE2 nuclear factor, erythroid 2
NTSR1 neurotensin receptor 1 (high affinity)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OCEL1 occludin/ELL domain containing 1
OTUD3 OTU deubiquitinase 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDH12 protocadherin 12
PKN1 protein kinase N1
POR P450 (cytochrome) oxidoreductase
PQLC2 PQ loop repeat containing 2
PRKG2 protein kinase, cGMP-dependent, type II
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
R3HCC1L R3H domain and coiled-coil containing 1-like
RNASE3 ribonuclease, RNase A family, 3
SCGB2A2 secretoglobin, family 2A, member 2
SERTAD3 SERTA domain containing 3
SIPA1 signal-induced proliferation-associated 1
SLC22A14 solute carrier family 22, member 14
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D2 TBC1 domain family, member 2
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TRAF2 TNF receptor-associated factor 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TSPAN13 tetraspanin 13
TUBA4B tubulin, alpha 4b
UCN urocortin
USP27X ubiquitin specific peptidase 27, X-linked
WFDC2 WAP four-disulfide core domain 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF222 zinc finger protein 222
ZNF468 zinc finger protein 468
ZNF606 zinc finger protein 606
ZNF669 zinc finger protein 669
ZNF747 zinc finger protein 747