early reproductive senescence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description loss of reproductive capacity occurring at an earlier than expected age (Mammalian Phenotype Ontology, MP_0008995)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008995
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Genes

21 gene mutations causing the early reproductive senescence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMHR2 anti-Mullerian hormone receptor, type II
CD59 CD59 molecule, complement regulatory protein
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
FANCA Fanconi anemia, complementation group A
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
FST follistatin
JMJD1C jumonji domain containing 1C
KITLG KIT ligand
MAGEL2 melanoma antigen family L2
NHLH2 nescient helix loop helix 2
NXF2 nuclear RNA export factor 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PER1 period circadian clock 1
PER2 period circadian clock 2
PFDN5 prefoldin subunit 5
SFTPC surfactant protein C
SPO11 SPO11 meiotic protein covalently bound to DSB
T T, brachyury homolog (mouse)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TOP3B topoisomerase (DNA) III beta