early endosome Gene Set

Dataset LOCATE Curated Protein Localization Annotations
Category proteomics
Type cellular component
Description A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. (Gene Ontology, GO_0005769)
External Link http://locate.imb.uq.edu.au/searchpages/HumanGO:0005769.shtml
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Genes

51 proteins localized to the early endosome cellular component in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.

Symbol Name
ACTN4 actinin, alpha 4
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ARL2 ADP-ribosylation factor-like 2
CD151 CD151 molecule (Raph blood group)
CHRM2 cholinergic receptor, muscarinic 2
CLIP1 CAP-GLY domain containing linker protein 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
DIAPH2 diaphanous-related formin 2
EEA1 early endosome antigen 1
EHD1 EH-domain containing 1
HAP1 huntingtin-associated protein 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
LNPEP leucyl/cystinyl aminopeptidase
NDRG1 N-myc downstream regulated 1
NISCH nischarin
OCRL oculocerebrorenal syndrome of Lowe
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB21 RAB21, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RBSN rabenosyn, RAB effector
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RUFY1 RUN and FYVE domain containing 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SNX1 sorting nexin 1
SNX13 sorting nexin 13
SNX15 sorting nexin 15
SNX16 sorting nexin 16
SNX17 sorting nexin 17
SNX18 sorting nexin 18
SNX2 sorting nexin 2
SNX27 sorting nexin family member 27
SNX3 sorting nexin 3
SNX4 sorting nexin 4
SNX5 sorting nexin 5
SNX6 sorting nexin 6
SPHAR S-phase response (cyclin related)
SPRY2 sprouty homolog 2 (Drosophila)
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STX8 syntaxin 8
SYT9 synaptotagmin IX
TOM1 target of myb1 (chicken)
TRAK1 trafficking protein, kinesin binding 1
VLDLR very low density lipoprotein receptor
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1