early endosome Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. (Gene Ontology, GO_0005769)
External Link http://amigo.geneontology.org/amigo/term/GO:0005769
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Genes

185 proteins localized to the early endosome cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR2 atypical chemokine receptor 2
ACKR3 atypical chemokine receptor 3
ACKR4 atypical chemokine receptor 4
ADRB1 adrenoceptor beta 1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD13B ankyrin repeat domain 13B
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANXA2 annexin A2
AOC3 amine oxidase, copper containing 3
AP1AR adaptor-related protein complex 1 associated regulatory protein
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOB apolipoprotein B
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AQP2 aquaporin 2 (collecting duct)
ARF6 ADP-ribosylation factor 6
ATP11A ATPase, class VI, type 11A
ATP11B ATPase, class VI, type 11B
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP9A ATPase, class II, type 9A
C16ORF62 chromosome 16 open reading frame 62
C1ORF210 chromosome 1 open reading frame 210
CCDC154 coiled-coil domain containing 154
CCDC53 coiled-coil domain containing 53
CCDC93 coiled-coil domain containing 93
CD1E CD1e molecule
CD4 CD4 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHMP1A charged multivesicular body protein 1A
CLCN3 chloride channel, voltage-sensitive 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CNTNAP2 contactin associated protein-like 2
COMMD1 copper metabolism (Murr1) domain containing 1
CORO1A coronin, actin binding protein, 1A
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
CYTIP cytohesin 1 interacting protein
DERL1 derlin 1
DERL2 derlin 2
DIAPH2 diaphanous-related formin 2
DNER delta/notch-like EGF repeat containing
DYSF dysferlin
EEA1 early endosome antigen 1
EPHA3 EPH receptor A3
EQTN equatorin, sperm acrosome associated
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM109A family with sequence similarity 109, member A
FAM109B family with sequence similarity 109, member B
FAM21A family with sequence similarity 21, member A
FAM21C family with sequence similarity 21, member C
FGD5 FYVE, RhoGEF and PH domain containing 5
FKBP15 FK506 binding protein 15, 133kDa
GJA1 gap junction protein, alpha 1, 43kDa
GPER1 G protein-coupled estrogen receptor 1
GRIPAP1 GRIP1 associated protein 1
HFE hemochromatosis
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KIAA0196 KIAA0196
KIAA0226 KIAA0226
KIAA0319 KIAA0319
KIAA0368 KIAA0368
KIAA1033 KIAA1033
KIF16B kinesin family member 16B
KIFC1 kinesin family member C1
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LIPG lipase, endothelial
LMTK2 lemur tyrosine kinase 2
LRP6 low density lipoprotein receptor-related protein 6
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MIB2 mindbomb E3 ubiquitin protein ligase 2
MICALL1 MICAL-like 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMGT1 membrane magnesium transporter 1
MVB12B multivesicular body subunit 12B
MYO1B myosin IB
MYO5A myosin VA (heavy chain 12, myoxin)
NF2 neurofibromin 2 (merlin)
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NISCH nischarin
NOX1 NADPH oxidase 1
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUMB numb homolog (Drosophila)
OCRL oculocerebrorenal syndrome of Lowe
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PRDX3 peroxiredoxin 3
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN23 protein tyrosine phosphatase, non-receptor type 23
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB14 RAB14, member RAS oncogene family
RAB17 RAB17, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB20 RAB20, member RAS oncogene family
RAB22A RAB22A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RABGAP1L RAB GTPase activating protein 1-like
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAP1A RAP1A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGEF1B RasGEF domain family, member 1B
RHOB ras homolog family member B
RHOD ras homolog family member D
RIN3 Ras and Rab interactor 3
RND2 Rho family GTPase 2
RNF11 ring finger protein 11
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RUSC1 RUN and SH3 domain containing 1
SAMD9L sterile alpha motif domain containing 9-like
SDCCAG3 serologically defined colon cancer antigen 3
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SNX12 sorting nexin 12
SNX13 sorting nexin 13
SNX16 sorting nexin 16
SNX17 sorting nexin 17
SNX27 sorting nexin family member 27
SNX3 sorting nexin 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SORT1 sortilin 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
STAMBP STAM binding protein
STEAP2 STEAP family member 2, metalloreductase
STX6 syntaxin 6
STX7 syntaxin 7
STX8 syntaxin 8
TF transferrin
TMEM127 transmembrane protein 127
TOM1 target of myb1 (chicken)
TRAK1 trafficking protein, kinesin binding 1
TRAK2 trafficking protein, kinesin binding 2
TRIM27 tripartite motif containing 27
TRIM3 tripartite motif containing 3
TSG101 tumor susceptibility 101
USP10 ubiquitin specific peptidase 10
USP8 ubiquitin specific peptidase 8
UTS2R urotensin 2 receptor
UVRAG UV radiation resistance associated
VAMP8 vesicle-associated membrane protein 8
VCAM1 vascular cell adhesion molecule 1
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WASF2 WAS protein family, member 2
WASH1 WAS protein family homolog 1
WDFY1 WD repeat and FYVE domain containing 1
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE9 zinc finger, FYVE domain containing 9