early endosome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. (Gene Ontology, GO_0005769)
Similar Terms
Downloads & Tools

Genes

190 proteins localized to the early endosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RUFY1 RUN and FYVE domain containing 1 0.663342
ZFYVE16 zinc finger, FYVE domain containing 16 0.663342
CLN3 ceroid-lipofuscinosis, neuronal 3 0.663342
SNX17 sorting nexin 17 0.663342
SNX16 sorting nexin 16 0.663342
SNX13 sorting nexin 13 0.663342
SNX12 sorting nexin 12 0.663342
ZFYVE9 zinc finger, FYVE domain containing 9 0.663342
PRDX3 peroxiredoxin 3 0.663342
ATP11B ATPase, class VI, type 11B 0.663342
DNER delta/notch-like EGF repeat containing 0.663342
KIAA0368 KIAA0368 0.663342
EPHB1 EPH receptor B1 0.663342
STEAP2 STEAP family member 2, metalloreductase 0.663342
RNF11 ring finger protein 11 0.663342
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.663342
CLIP3 CAP-GLY domain containing linker protein 3 0.663342
WDFY1 WD repeat and FYVE domain containing 1 0.663342
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.663342
GPER1 G protein-coupled estrogen receptor 1 0.663342
RBSN rabenosyn, RAB effector 0.663342
ARF6 ADP-ribosylation factor 6 0.663342
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.663342
VCAM1 vascular cell adhesion molecule 1 0.663342
SNX27 sorting nexin family member 27 0.663342
SNX6 sorting nexin 6 0.663342
ATP9A ATPase, class II, type 9A 0.663342
TICAM2 toll-like receptor adaptor molecule 2 0.663342
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.663342
MAP2K2 mitogen-activated protein kinase kinase 2 0.663342
MAP2K1 mitogen-activated protein kinase kinase 1 0.663342
CYTIP cytohesin 1 interacting protein 0.663342
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.663342
SNX3 sorting nexin 3 0.663342
SNX1 sorting nexin 1 0.663342
SNX5 sorting nexin 5 0.663342
SNX4 sorting nexin 4 0.663342
SNX8 sorting nexin 8 0.663342
PML promyelocytic leukemia 0.663342
TSG101 tumor susceptibility 101 0.663342
EHD1 EH-domain containing 1 0.663342
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.663342
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.663342
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.663342
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough 0.663342
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.663342
CD1E CD1e molecule 0.663342
CLCN3 chloride channel, voltage-sensitive 3 0.663342
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 0.663342
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.663342
ZFYVE28 zinc finger, FYVE domain containing 28 0.663342
STX6 syntaxin 6 0.663342
UVRAG UV radiation resistance associated 0.663342
NISCH nischarin 0.663342
RAB21 RAB21, member RAS oncogene family 0.663342
RABGAP1L RAB GTPase activating protein 1-like 0.663342
KIAA0319 KIAA0319 0.663342
PARM1 prostate androgen-regulated mucin-like protein 1 0.663342
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.663342
RAB14 RAB14, member RAS oncogene family 0.663342
PMEPA1 prostate transmembrane protein, androgen induced 1 0.663342
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.663342
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.663342
TOM1 target of myb1 (chicken) 0.663342
MAPK3 mitogen-activated protein kinase 3 0.663342
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.663342
MAPK1 mitogen-activated protein kinase 1 0.663342
KIAA0226 KIAA0226 0.663342
RAB5A RAB5A, member RAS oncogene family 0.663342
CHMP1A charged multivesicular body protein 1A 0.663342
STAMBP STAM binding protein 0.663342
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.663342
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.663342
KIF16B kinesin family member 16B 0.663342
KDR kinase insert domain receptor 0.663342
HFE hemochromatosis 0.663342
USP10 ubiquitin specific peptidase 10 0.663342
RAB31 RAB31, member RAS oncogene family 0.663342
ADRB1 adrenoceptor beta 1 0.663342
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 0.663342
EPHA3 EPH receptor A3 0.663342
TF transferrin 0.663342
TRAK1 trafficking protein, kinesin binding 1 0.663342
AP1AR adaptor-related protein complex 1 associated regulatory protein 0.663342
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.663342
RIN3 Ras and Rab interactor 3 0.663342
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.663342
EEA1 early endosome antigen 1 0.663342
LMTK2 lemur tyrosine kinase 2 0.663342
HPS6 Hermansky-Pudlak syndrome 6 0.663342
RAP1A RAP1A, member of RAS oncogene family 0.663342
LDLR low density lipoprotein receptor 0.663342
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.663342
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.663342
USP8 ubiquitin specific peptidase 8 0.663342
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.663342
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.663342
FAM21C family with sequence similarity 21, member C 0.663342
OCRL oculocerebrorenal syndrome of Lowe 0.663342
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.663342
TMEM165 transmembrane protein 165 0.663342
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.663342
FAM109B family with sequence similarity 109, member B 0.663342
FAM109A family with sequence similarity 109, member A 0.663342
RAB22A RAB22A, member RAS oncogene family 0.663342
DIAPH2 diaphanous-related formin 2 0.663342
CXCR4 chemokine (C-X-C motif) receptor 4 0.663342
PCSK9 proprotein convertase subtilisin/kexin type 9 0.663342
PLA2G4B phospholipase A2, group IVB (cytosolic) 0.663342
WASH1 WAS protein family homolog 1 0.663342
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.663342
JMJD7 jumonji domain containing 7 0.663342
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.237908
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.237908
RAB38 RAB38, member RAS oncogene family 0.237908
CD207 CD207 molecule, langerin 0.237908
RAB32 RAB32, member RAS oncogene family 0.237908
RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.237908
MMGT1 membrane magnesium transporter 1 0.237908
FIG4 FIG4 phosphoinositide 5-phosphatase 0.237908
B2M beta-2-microglobulin 0.237908
SORT1 sortilin 1 0.237908
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.237908
MTMR4 myotubularin related protein 4 0.237908
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.237908
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.237908
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.237908
CD4 CD4 molecule 0.237908
MVB12B multivesicular body subunit 12B 0.237908
FAM21A family with sequence similarity 21, member A 0.237908
CNTNAP2 contactin associated protein-like 2 0.237908
MYO1B myosin IB 0.237908
WASH6P WAS protein family homolog 6 pseudogene 0.237908
EPHA4 EPH receptor A4 0.237908
CD8B CD8b molecule 0.237908
LAMP5 lysosomal-associated membrane protein family, member 5 0.237908
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.237908
HLA-E major histocompatibility complex, class I, E 0.237908
HLA-C major histocompatibility complex, class I, C 0.237908
WASH4P WAS protein family homolog 4 pseudogene 0.237908
ECE1 endothelin converting enzyme 1 0.237908
APOB apolipoprotein B 0.237908
APOE apolipoprotein E 0.237908
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.237908
LNPEP leucyl/cystinyl aminopeptidase 0.237908
APOC2 apolipoprotein C-II 0.237908
APOC3 apolipoprotein C-III 0.237908
NOX1 NADPH oxidase 1 0.237908
RUSC1 RUN and SH3 domain containing 1 0.237908
TMEM163 transmembrane protein 163 0.237908
WLS wntless Wnt ligand secretion mediator 0.237908
VAMP8 vesicle-associated membrane protein 8 0.237908
SYNDIG1 synapse differentiation inducing 1 0.237908
APOA4 apolipoprotein A-IV 0.237908
VAC14 Vac14 homolog (S. cerevisiae) 0.237908
HLA-B major histocompatibility complex, class I, B 0.237908
APOA2 apolipoprotein A-II 0.237908
NF2 neurofibromin 2 (merlin) 0.237908
HLA-A major histocompatibility complex, class I, A 0.237908
APOA1 apolipoprotein A-I 0.237908
HLA-G major histocompatibility complex, class I, G 0.237908
HLA-F major histocompatibility complex, class I, F 0.237908
KCTD7 potassium channel tetramerization domain containing 7 0.237908
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.237908
NRP1 neuropilin 1 0.098109
SIAH2 siah E3 ubiquitin protein ligase 2 0.03318
SIAH1 siah E3 ubiquitin protein ligase 1 0.03318
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.03318
UTS2R urotensin 2 receptor 0.03318
LRP6 low density lipoprotein receptor-related protein 6 0.03318
SAMD9L sterile alpha motif domain containing 9-like 0.03318
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.03318
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.03318
DERL2 derlin 2 0.03318
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.03318
TMEM184A transmembrane protein 184A 0.03318
EQTN equatorin, sperm acrosome associated 0.03318
NUMB numb homolog (Drosophila) 0.03318
GJA1 gap junction protein, alpha 1, 43kDa 0.03318
ANXA2 annexin A2 0.03318
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.03318
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 0.03318
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.03318
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 0.03318
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 0.03318
FZD5 frizzled class receptor 5 0.03318
RND2 Rho family GTPase 2 0.03318
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.03318
AQP2 aquaporin 2 (collecting duct) 0.03318
DERL1 derlin 1 0.03318