dystroglycan complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin. (Gene Ontology, GO_0016011)
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Genes

7 proteins localized to the dystroglycan complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.237908
SGCE sarcoglycan, epsilon 0.237908
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.237908
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.237908
SGCZ sarcoglycan, zeta 0.237908
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.03318
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.03318