dydrogesterone-2156 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dydrogesterone-2156 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM8 ADAM metallopeptidase domain 8
AGRP agouti related neuropeptide
AHNAK AHNAK nucleoprotein
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALK anaplastic lymphoma receptor tyrosine kinase
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP9 aquaporin 9
C11ORF16 chromosome 11 open reading frame 16
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CADM3 cell adhesion molecule 3
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CASZ1 castor zinc finger 1
CCND1 cyclin D1
CDRT1 CMT1A duplicated region transcript 1
CLIP2 CAP-GLY domain containing linker protein 2
CNGB1 cyclic nucleotide gated channel beta 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
DMWD dystrophia myotonica, WD repeat containing
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNASE2 deoxyribonuclease II, lysosomal
DPYSL3 dihydropyrimidinase-like 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHD3 EH-domain containing 3
EIF1 eukaryotic translation initiation factor 1
EPX eosinophil peroxidase
EXO5 exonuclease 5
FBXO40 F-box protein 40
FCAR Fc fragment of IgA receptor
FGF2 fibroblast growth factor 2 (basic)
FMO5 flavin containing monooxygenase 5
FZD1 frizzled class receptor 1
HAMP hepcidin antimicrobial peptide
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H1D histone cluster 1, H1d
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA10 homeobox A10
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KIAA0226 KIAA0226
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LIN7B lin-7 homolog B (C. elegans)
MAP1A microtubule-associated protein 1A
MC5R melanocortin 5 receptor
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MRPS18C mitochondrial ribosomal protein S18C
MT1H metallothionein 1H
MTA1 metastasis associated 1
MTUS1 microtubule associated tumor suppressor 1
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NDE1 nudE neurodevelopment protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPY2R neuropeptide Y receptor Y2
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDE4DIP phosphodiesterase 4D interacting protein
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PGBD5 piggyBac transposable element derived 5
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLAGL2 pleiomorphic adenoma gene-like 2
PVR poliovirus receptor
RANGAP1 Ran GTPase activating protein 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REC8 REC8 meiotic recombination protein
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RGS4 regulator of G-protein signaling 4
RUNDC3B RUN domain containing 3B
SH3D21 SH3 domain containing 21
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SKAP1 src kinase associated phosphoprotein 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAB2 stabilin 2
SULT4A1 sulfotransferase family 4A, member 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TLN2 talin 2
TMEM62 transmembrane protein 62
TMEM8B transmembrane protein 8B
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TTLL7 tubulin tyrosine ligase-like family member 7
TUBB2A tubulin, beta 2A class IIa
TYMP thymidine phosphorylase
ZC3H7B zinc finger CCCH-type containing 7B
ZIC3 Zic family member 3
ZMYND8 zinc finger, MYND-type containing 8
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADM adrenomedullin
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG9A autophagy related 9A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT1
C17ORF80 chromosome 17 open reading frame 80
CCDC176 coiled-coil domain containing 176
CCDC186 coiled-coil domain containing 186
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHPF chondroitin polymerizing factor
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CTNNBIP1 catenin, beta interacting protein 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGKG diacylglycerol kinase, gamma 90kDa
DHCR7 7-dehydrocholesterol reductase
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAL4 dynein, axonemal, light chain 4
DNM3 dynamin 3
DNMBP dynamin binding protein
DRAM1 DNA-damage regulated autophagy modulator 1
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
EGR2 early growth response 2
EPHB6 EPH receptor B6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM206A family with sequence similarity 206, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
GRIP2 glutamate receptor interacting protein 2
GSTA4 glutathione S-transferase alpha 4
GSTT1 glutathione S-transferase theta 1
GTF2I general transcription factor IIi
HCAR3 hydroxycarboxylic acid receptor 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IMPAD1 inositol monophosphatase domain containing 1
INSIG2 insulin induced gene 2
KPNA5 karyopherin alpha 5 (importin alpha 6)
LINS lines homolog (Drosophila)
LOC729164 hCG1732469
LRP2 low density lipoprotein receptor-related protein 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MOCS3 molybdenum cofactor synthesis 3
MYOZ3 myozenin 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU1 sialidase 1 (lysosomal sialidase)
ODF2 outer dense fiber of sperm tails 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD7 PDZ domain containing 7
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PTCD2 pentatricopeptide repeat domain 2
RAB23 RAB23, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SNAI1 snail family zinc finger 1
SYCP2 synaptonemal complex protein 2
TAGLN transgelin
TBC1D19 TBC1 domain family, member 19
TEC tec protein tyrosine kinase
THBS3 thrombospondin 3
TLR4 toll-like receptor 4
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TNNT1 troponin T type 1 (skeletal, slow)
TRIM25 tripartite motif containing 25
TWISTNB TWIST neighbor
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UPB1 ureidopropionase, beta
ZBTB38 zinc finger and BTB domain containing 38
ZNF10 zinc finger protein 10
ZNF219 zinc finger protein 219
ZNF225 zinc finger protein 225
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254
ZNF345 zinc finger protein 345
ZNF747 zinc finger protein 747
ZSCAN16 zinc finger and SCAN domain containing 16